Structure-based cleavage mechanism of Thermusthermophilus argonaute DNA guide strand-mediated DNA target cleavage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 2, 2014, Pages 652-657

  Sheng, Gang ^a   Zhao, Hongtu ^a,b   Wang, Jiuyu ^a   Rao, Yu ^a   Tian, Wenwen ^a,b   Swarts, Daan C ^c   Van Der Oost, John ^c   Patel, Dinshaw J ^d   Wang, Yanli ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Bacterial Argonaute; Catalytic mechanism; DNA guide DNA target

Indexed keywords

ARGONAUTE PROTEIN; DNA; PHOSPHATE; WATER;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; NONHUMAN; PRIORITY JOURNAL; THERMUS THERMOPHILUS;

BACTERIAL ARGONAUTE; CATALYTIC MECHANISM; DNA GUIDE-DNA TARGET;

ARGONAUTE PROTEINS; CATALYSIS; DNA, BACTERIAL; MODELS, MOLECULAR; PROTEIN CONFORMATION; THERMUS THERMOPHILUS;

EID: 84892612595     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321032111     Document Type: Article

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