Diverse Non-genetic, Allele-Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain

Neuron

Volumn 93, Issue 5, 2017, Pages 1094-1109.e7

  Huang, Wei Chao ^a   Ferris, Elliott ^a   Cheng, Tong ^a   Hörndli, Cornelia Stacher ^a   Gleason, Kelly ^c   Tamminga, Carol ^c   Wagner, Janice D ^d   Boucher, Kenneth M ^a,b   Christian, Jan L ^a   Gregg, Christopher ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

allele specific expression; autism; behavioral genetics; brain development; brain epigenetics; genomic imprinting; mental illness; monoallelic; random monoallelic expression; transcriptome

Indexed keywords

ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL SPECIFICITY; CELLS BY BODY ANATOMY; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; GENE EXPRESSION; GENE MUTATION; GENE STRUCTURE; GENETIC RISK; GENETIC VARIABILITY; GENOME IMPRINTING; GENOMICS; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; MACACA; MAMMAL CELL; MENTAL DISEASE; MOSAICISM; MOUSE; MUTANT; NEWBORN; NONHUMAN; ANIMAL; BRAIN; GENETIC VARIATION; GENETICS; GENOTYPE; MAMMAL; METABOLISM; MUTATION; PHYSIOLOGY; TRANSGENIC MOUSE; X CHROMOSOME INACTIVATION;

ALLELES; ANIMALS; BRAIN; GENETIC VARIATION; GENOMIC IMPRINTING; GENOTYPE; HUMANS; MACACA; MAMMALS; MICE, TRANSGENIC; MUTATION; X CHROMOSOME INACTIVATION;

EID: 85013628374     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2017.01.033     Document Type: Article

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