A high-throughput, image-based screen to identify kinases involved in brown adipocyte development

Science Signaling

Volumn 10, Issue 466, 2017, Pages

  Perdikari, Aliki ^a   Kulenkampff, Elisabeth ^a   Rudigier, Carla ^a   Neubauer, Heike ^b   Luippold, Gerd ^b   Redemann, Norbert ^b   Wolfrum, Christian ^a  

^a ETH ZURICH   (Switzerland)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5' AMP ACTIVATED KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II GAMMA; DEATH ASSOCIATED PROTEIN KINASE; DEATH ASSOCIATED PROTEIN KINASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INOSITOL TRISPHOSPHATE 3 KINASE; INOSITOL TRISPHOSPHATE 3 KINASE B; INSULIN RECEPTOR; JANUS KINASE 3; MACROPHAGE ACTIVATING FACTOR; MACROPHAGE STIMULATING 1 RECEPTOR; MAGUK P55 SUBFAMILY MEMBER 5 PROTEIN; MEMBRANE ASSOCIATED GUANYLATE CYCLASE KINASE; MICROTUBULE AFFINITY REGULATING KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PHOSPHATIDYLINOSITOL 4 PHOSPHATE 3 KINASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE 3 KINASE C2B; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE TYPE I B; PHOSPHOTRANSFERASE; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES PROTOONCOGENE 1 RECEPTOR TYROSINE KINASE; S6 KINASE BETA 1; TRIBBLE PSEUDOKINASE 3; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOCYTE; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; HIGH THROUGHPUT SCREENING; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LENTIVIRINAE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ZUCKER DIABETIC FATTY RAT; ANIMAL; CELL CULTURE; CLASSIFICATION; CYTOLOGY; GENETICS; METABOLISM; MOUSE; PROCEDURES; PROTEIN SUBUNIT; PROTEOMICS; RNA INTERFERENCE; WESTERN BLOTTING;

ADIPOCYTES, BROWN; ADIPOSE TISSUE, BROWN; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; HIGH-THROUGHPUT SCREENING ASSAYS; MICE; PHOSPHOTRANSFERASES; PROTEIN SUBUNITS; PROTEOMICS; RNA INTERFERENCE;

EID: 85013491978     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaf5357     Document Type: Article

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