-
1
-
-
77955883153
-
Complement: A key system for immune surveillance and homeostasis
-
Ricklin D, Hajishengallis G, Yang K, Lambris JD: Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11: 785-797, 2010
-
(2010)
Nat Immunol
, vol.11
, pp. 785-797
-
-
Ricklin, D.1
Hajishengallis, G.2
Yang, K.3
Lambris, J.D.4
-
2
-
-
84930053899
-
Molecules Great and Small: The Complement System
-
Mathern DR, Heeger PS: Molecules Great and Small: The Complement System. Clin J Am Soc Nephrol 10: 1636-1650, 2015
-
(2015)
Clin J am Soc Nephrol
, vol.10
, pp. 1636-1650
-
-
Mathern, D.R.1
Heeger, P.S.2
-
3
-
-
0035810399
-
Complement. First of two parts
-
Walport MJ: Complement. First of two parts. N Engl J Med 344: 1058-1066, 2001
-
(2001)
N Engl J Med
, vol.344
, pp. 1058-1066
-
-
Walport, M.J.1
-
4
-
-
37349066319
-
Complement deficiencies and systemic lupus erythematosus
-
Truedsson L, Bengtsson AA, Sturfelt G: Complement deficiencies and systemic lupus erythematosus. Autoimmunity 40: 560-566, 2007
-
(2007)
Autoimmunity
, vol.40
, pp. 560-566
-
-
Truedsson, L.1
Bengtsson, A.A.2
Sturfelt, G.3
-
5
-
-
2542505506
-
The role of complement in the development of systemic lupus erythematosus
-
Manderson AP, Botto M, Walport MJ: The role of complement in the development of systemic lupus erythematosus. Annu Rev Immunol 22: 431-456, 2004
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 431-456
-
-
Manderson, A.P.1
Botto, M.2
Walport, M.J.3
-
6
-
-
0023213554
-
Activation of the alternative pathway of complement by human serum IgA
-
Hiemstra PS, Gorter A, Stuurman ME, Van Es LA, Daha MR: Activation of the alternative pathway of complement by human serum IgA. Eur J Immunol 17: 321-326, 1987
-
(1987)
Eur J Immunol
, vol.17
, pp. 321-326
-
-
Hiemstra, P.S.1
Gorter, A.2
Stuurman, M.E.3
Van Es, L.A.4
Daha, M.R.5
-
7
-
-
0028074679
-
Antibody-mediated complement activation on nucleated cells. A quantitative analysis of the individual reaction steps
-
Ollert MW, Kadlec JV, David K, Petrella EC, Bredehorst R, Vogel CW: Antibody-mediated complement activation on nucleated cells. A quantitative analysis of the individual reaction steps. J Immunol 153: 2213-2221, 1994
-
(1994)
J Immunol
, vol.153
, pp. 2213-2221
-
-
Ollert, M.W.1
Kadlec, J.V.2
David, K.3
Petrella, E.C.4
Bredehorst, R.5
Vogel, C.W.6
-
8
-
-
34848878632
-
Complement 3 is involved in changing the phenotype of human glomerular mesangial cells
-
Wan JX, Fukuda N, Endo M, Tahira Y, Yao EH, Matsuda H, Ueno T, Matsumoto K: Complement 3 is involved in changing the phenotype of human glomerular mesangial cells. J Cell Physiol 213: 495-501, 2007
-
(2007)
J Cell Physiol
, vol.213
, pp. 495-501
-
-
Wan, J.X.1
Fukuda, N.2
Endo, M.3
Tahira, Y.4
Yao, E.H.5
Matsuda, H.6
Ueno, T.7
Matsumoto, K.8
-
9
-
-
33846495181
-
C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion
-
Thurman JM, Lenderink AM, Royer PA, Coleman KE, Zhou J, Lambris JD, Nemenoff RA, Quigg RJ, Holers VM: C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion. J Immunol 178: 1819-1828, 2007
-
(2007)
J Immunol
, vol.178
, pp. 1819-1828
-
-
Thurman, J.M.1
Lenderink, A.M.2
Royer, P.A.3
Coleman, K.E.4
Zhou, J.5
Lambris, J.D.6
Nemenoff, R.A.7
Quigg, R.J.8
Holers, V.M.9
-
10
-
-
0028014275
-
Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells
-
Benzaquen LR, Nicholson-Weller A, Halperin JA: Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells. J Exp Med 179: 985-992, 1994
-
(1994)
J Exp Med
, vol.179
, pp. 985-992
-
-
Benzaquen, L.R.1
Nicholson-Weller, A.2
Halperin, J.A.3
-
11
-
-
0023091115
-
Activation of glomerular mesangial cells by the terminal membrane attack complex of complement
-
Lovett DH, Haensch GM, Goppelt M, Resch K, Gemsa D: Activation of glomerular mesangial cells by the terminal membrane attack complex of complement. J Immunol 138: 2473-2480, 1987
-
(1987)
J Immunol
, vol.138
, pp. 2473-2480
-
-
Lovett, D.H.1
Haensch, G.M.2
Goppelt, M.3
Resch, K.4
Gemsa, D.5
-
12
-
-
0022539964
-
Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells
-
Adler S, Baker PJ, Johnson RJ, Ochi RF, Pritzl P, Couser WG: Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells. J Clin Invest 77: 762-767, 1986
-
(1986)
J Clin Invest
, vol.77
, pp. 762-767
-
-
Adler, S.1
Baker, P.J.2
Johnson, R.J.3
Ochi, R.F.4
Pritzl, P.5
Couser, W.G.6
-
13
-
-
0022551108
-
Complementinduced glomerular epithelial cell injury. Role of the membrane attack complex in rat membranous nephropathy
-
Cybulsky AV, Rennke HG, Feintzeig ID, Salant DJ: Complementinduced glomerular epithelial cell injury. Role of the membrane attack complex in rat membranous nephropathy. J Clin Invest 77: 1096-1107, 1986
-
(1986)
J Clin Invest
, vol.77
, pp. 1096-1107
-
-
Cybulsky, A.V.1
Rennke, H.G.2
Feintzeig, I.D.3
Salant, D.J.4
-
14
-
-
70349437186
-
Complement regulators and inhibitory proteins
-
Zipfel PF, Skerka C: Complement regulators and inhibitory proteins. Nat Rev Immunol 9: 729-740, 2009
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 729-740
-
-
Zipfel, P.F.1
Skerka, C.2
-
15
-
-
0019458388
-
Fourth component of human complement: Studies of an amine-sensitive site comprised of a thiol component
-
Janatova J, Tack BF: Fourth component of human complement: studies of an amine-sensitive site comprised of a thiol component. Biochemistry 20: 2394-2402, 1981
-
(1981)
Biochemistry
, vol.20
, pp. 2394-2402
-
-
Janatova, J.1
Tack, B.F.2
-
16
-
-
0028239796
-
Localization of the complement regulatory proteins in the normal human kidney
-
Ichida S, Yuzawa Y, Okada H, Yoshioka K, Matsuo S: Localization of the complement regulatory proteins in the normal human kidney. Kidney Int 46: 89-96, 1994
-
(1994)
Kidney Int
, vol.46
, pp. 89-96
-
-
Ichida, S.1
Yuzawa, Y.2
Okada, H.3
Yoshioka, K.4
Matsuo, S.5
-
17
-
-
79952612300
-
Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement
-
Kajander T, Lehtinen MJ, Hyvärinen S, Bhattacharjee A, Leung E, Isenman DE, Meri S, Goldman A, Jokiranta TS: Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement. Proc Natl Acad Sci U S A 108: 2897-2902, 2011
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 2897-2902
-
-
Kajander, T.1
Lehtinen, M.J.2
Hyvärinen, S.3
Bhattacharjee, A.4
Leung, E.5
Isenman, D.E.6
Meri, S.7
Goldman, A.8
Jokiranta, T.S.9
-
18
-
-
84930819375
-
Factor H-related proteins determine complement-activating surfaces
-
Józsi M, Tortajada A, Uzonyi B, Goicoechea de Jorge E, Rodríguez de Córdoba S: Factor H-related proteins determine complement-activating surfaces. Trends Immunol 36: 374-384, 2015
-
(2015)
Trends Immunol
, vol.36
, pp. 374-384
-
-
Józsi, M.1
Tortajada, A.2
Uzonyi, B.3
Goicoechea De Jorge, E.4
Rodríguez De Córdoba, S.5
-
19
-
-
32444446595
-
Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion
-
Thurman JM, Ljubanovi_c D, Royer PA, Kraus DM, Molina H, Barry NP, Proctor G, Levi M, Holers VM: Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion. J Clin Invest 116: 357-368, 2006
-
(2006)
J Clin Invest
, vol.116
, pp. 357-368
-
-
Thurman, J.M.1
Ljubanovic, D.2
Royer, P.A.3
Kraus, D.M.4
Molina, H.5
Barry, N.P.6
Proctor, G.7
Levi, M.8
Holers, V.M.9
-
20
-
-
33644928993
-
Local extravascular pool of C3 is a determinant of postischemic acute renal failure
-
Farrar CA, Zhou W, Lin T, Sacks SH: Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J 20: 217-226, 2006
-
(2006)
FASEB J
, vol.20
, pp. 217-226
-
-
Farrar, C.A.1
Zhou, W.2
Lin, T.3
Sacks, S.H.4
-
21
-
-
84865428866
-
Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway
-
Krisinger MJ, Goebeler V, Lu Z, Meixner SC, Myles T, Pryzdial EL, Conway EM: Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway. Blood 120: 1717-1725, 2012
-
(2012)
Blood
, vol.120
, pp. 1717-1725
-
-
Krisinger, M.J.1
Goebeler, V.2
Lu, Z.3
Meixner, S.C.4
Myles, T.5
Pryzdial, E.L.6
Conway, E.M.7
-
22
-
-
84957642167
-
Annexin A2 Enhances Complement Activation by Inhibiting Factor H
-
Renner B, Tong HH, Laskowski J, Jonscher K, Goetz L, Woolaver R, Hannan J, Li YX, Hourcade D, Pickering MC, Holers VM, Thurman JM: Annexin A2 Enhances Complement Activation by Inhibiting Factor H. J Immunol 196: 1355-1365, 2016
-
(2016)
J Immunol
, vol.196
, pp. 1355-1365
-
-
Renner, B.1
Tong, H.H.2
Laskowski, J.3
Jonscher, K.4
Goetz, L.5
Woolaver, R.6
Hannan, J.7
Li, Y.X.8
Hourcade, D.9
Pickering, M.C.10
Holers, V.M.11
Thurman, J.M.12
-
23
-
-
84883832799
-
A Role of Polymorphonuclear Leukocytes and Complement in Nephrotoxic Nephritis
-
Cochrane CG, Unanue ER, Dixon FJ: A Role of Polymorphonuclear Leukocytes and Complement in Nephrotoxic Nephritis. J Exp Med 122: 99-116, 1965
-
(1965)
J Exp Med
, vol.122
, pp. 99-116
-
-
Cochrane, C.G.1
Unanue, E.R.2
Dixon, F.J.3
-
24
-
-
0016022742
-
Immunopathology and glomerulonephritis
-
Wilson CB, Dixon FJ: Immunopathology and glomerulonephritis. Annu Rev Med 25: 83-98, 1974
-
(1974)
Annu Rev Med
, vol.25
, pp. 83-98
-
-
Wilson, C.B.1
Dixon, F.J.2
-
25
-
-
84946046875
-
C4d as a Diagnostic Tool in ProliferativeGN
-
Sethi S, Nasr SH, De Vriese AS, Fervenza FC: C4d as a Diagnostic Tool in ProliferativeGN. J AmSocNephrol 26: 2852-2859, 2015
-
(2015)
J Amsocnephrol
, vol.26
, pp. 2852-2859
-
-
Sethi, S.1
Nasr, S.H.2
De Vriese, A.S.3
Fervenza, F.C.4
-
26
-
-
0015962394
-
Glomerular complement components in human glomerulonephritis
-
Verroust PJ, Wilson CB, Cooper NR, Edgington TS, Dixon FJ: Glomerular complement components in human glomerulonephritis. J Clin Invest 53: 77-84, 1974
-
(1974)
J Clin Invest
, vol.53
, pp. 77-84
-
-
Verroust, P.J.1
Wilson, C.B.2
Cooper, N.R.3
Edgington, T.S.4
Dixon, F.J.5
-
27
-
-
84888641200
-
C3 glomerulopathy: Consensus report
-
Pickering MC, D’Agati VD, Nester CM, Smith RJ, Haas M, Appel GB, Alpers CE, Bajema IM, Bedrosian C, Braun M, Doyle M, Fakhouri F, Fervenza FC, Fogo AB, Frémeaux-Bacchi V, Gale DP, Goicoechea de Jorge E, Griffin G, Harris CL, Holers VM, Johnson S, Lavin PJ, Medjeral-Thomas N, Paul Morgan B, Nast CC, Noel LH, Peters DK, Rodríguez de Córdoba S, Servais A, Sethi S, Song WC, Tamburini P, Thurman JM, Zavros M, Cook HT: C3 glomerulopathy: consensus report. Kidney Int 84: 1079-1089, 2013
-
(2013)
Kidney Int
, vol.84
, pp. 1079-1089
-
-
Pickering, M.C.1
D’Agati, V.D.2
Nester, C.M.3
Smith, R.J.4
Haas, M.5
Appel, G.B.6
Alpers, C.E.7
Bajema, I.M.8
Bedrosian, C.9
Braun, M.10
Doyle, M.11
Fakhouri, F.12
Fervenza, F.C.13
Fogo, A.B.14
Frémeaux-Bacchi, V.15
Gale, D.P.16
Goicoechea De Jorge, E.17
Griffin, G.18
Harris, C.L.19
Holers, V.M.20
Johnson, S.21
Lavin, P.J.22
Medjeral-Thomas, N.23
Paul Morgan, B.24
Nast, C.C.25
Noel, L.H.26
Peters, D.K.27
Rodríguez De Córdoba, S.28
Servais, A.29
Sethi, S.30
Song, W.C.31
Tamburini, P.32
Thurman, J.M.33
Zavros, M.34
Cook, H.T.35
more..
-
28
-
-
0025907796
-
Diagnostic significance of hypocomplementemia
-
Hebert LA, Cosio FG, Neff JC: Diagnostic significance of hypocomplementemia. Kidney Int 39: 811-821, 1991
-
(1991)
Kidney Int
, vol.39
, pp. 811-821
-
-
Hebert, L.A.1
Cosio, F.G.2
Neff, J.C.3
-
29
-
-
0015023327
-
Continuing C3 breakdown after bilateral nephrectomy in patients with membrano-proliferative glomerulonephritis
-
Vallota EH, Forristal J, Spitzer RE, Davis NC, West CD: Continuing C3 breakdown after bilateral nephrectomy in patients with membrano-proliferative glomerulonephritis. J Clin Invest 50: 552-558, 1971
-
(1971)
J Clin Invest
, vol.50
, pp. 552-558
-
-
Vallota, E.H.1
Forristal, J.2
Spitzer, R.E.3
Davis, N.C.4
West, C.D.5
-
30
-
-
0023888694
-
Increased levels of plasma anaphylatoxins in systemic lupus erythematosus predict flares of the disease and may elicit vascular injury in lupus cerebritis
-
Hopkins P, Belmont HM, Buyon J, Philips M, Weissmann G, Abramson SB: Increased levels of plasma anaphylatoxins in systemic lupus erythematosus predict flares of the disease and may elicit vascular injury in lupus cerebritis. Arthritis Rheum 31: 632-641, 1988
-
(1988)
Arthritis Rheum
, vol.31
, pp. 632-641
-
-
Hopkins, P.1
Belmont, H.M.2
Buyon, J.3
Philips, M.4
Weissmann, G.5
Abramson, S.B.6
-
31
-
-
0026568826
-
Urinary C3dg and C5b-9 indicate active immune disease in human membranous nephropathy
-
Brenchley PE, Coupes B, Short CD, O’Donoghue DJ, Ballardie FW, Mallick NP: Urinary C3dg and C5b-9 indicate active immune disease in human membranous nephropathy. Kidney Int 41: 933-937, 1992
-
(1992)
Kidney Int
, vol.41
, pp. 933-937
-
-
Brenchley, P.E.1
Coupes, B.2
Short, C.D.3
O’Donoghue, D.J.4
Ballardie, F.W.5
Mallick, N.P.6
-
32
-
-
84930472724
-
Soluble c5b-9 as a biomarker for complement activation in atypical hemolytic uremic syndrome
-
Bu F, Meyer NC, Zhang Y, Borsa NG, Thomas C, Nester C, Smith RJ: Soluble c5b-9 as a biomarker for complement activation in atypical hemolytic uremic syndrome. Am J Kidney Dis 65: 968-969, 2015
-
(2015)
Am J Kidney Dis
, vol.65
, pp. 968-969
-
-
Bu, F.1
Meyer, N.C.2
Zhang, Y.3
Borsa, N.G.4
Thomas, C.5
Nester, C.6
Smith, R.J.7
-
33
-
-
0028952777
-
Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency
-
Høgåsen K, Jansen JH, Mollnes TE, Hovdenes J, Harboe M: Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency. J Clin Invest 95: 1054-1061, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 1054-1061
-
-
Høgåsen, K.1
Jansen, J.H.2
Mollnes, T.E.3
Hovdenes, J.4
Harboe, M.5
-
34
-
-
0034650431
-
Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B
-
Watanabe H, Garnier G, Circolo A, Wetsel RA, Ruiz P, Holers VM, Boackle SA, Colten HR, Gilkeson GS: Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B. J Immunol 164: 786-794, 2000
-
(2000)
J Immunol
, vol.164
, pp. 786-794
-
-
Watanabe, H.1
Garnier, G.2
Circolo, A.3
Wetsel, R.A.4
Ruiz, P.5
Holers, V.M.6
Boackle, S.A.7
Colten, H.R.8
Gilkeson, G.S.9
-
35
-
-
0036699540
-
Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
-
Pickering MC, Cook HT, Warren J, Bygrave AE, Moss J, Walport MJ, Botto M: Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat Genet 31: 424-428, 2002
-
(2002)
Nat Genet
, vol.31
, pp. 424-428
-
-
Pickering, M.C.1
Cook, H.T.2
Warren, J.3
Bygrave, A.E.4
Moss, J.5
Walport, M.J.6
Botto, M.7
-
36
-
-
33847052568
-
Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies
-
Xiao H, Schreiber A, Heeringa P, Falk RJ, Jennette JC: Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies. Am J Pathol 170: 52-64, 2007
-
(2007)
Am J Pathol
, vol.170
, pp. 52-64
-
-
Xiao, H.1
Schreiber, A.2
Heeringa, P.3
Falk, R.J.4
Jennette, J.C.5
-
37
-
-
34548381835
-
The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy
-
Lenderink AM, Liegel K, Ljubanovi_c D, Coleman KE, Gilkeson GS, Holers VM, Thurman JM: The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy. Am J Physiol Renal Physiol 293: F555-F564, 2007
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F555-F564
-
-
Lenderink, A.M.1
Liegel, K.2
Ljubanovic, D.3
Coleman, K.E.4
Gilkeson, G.S.5
Holers, V.M.6
Thurman, J.M.7
-
38
-
-
0025354456
-
Soluble human complement receptor type 1: In vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis
-
Weisman HF, Bartow T, Leppo MK, Marsh HC Jr, Carson GR, Concino MF, Boyle MP, Roux KH, Weisfeldt ML, Fearon DT: Soluble human complement receptor type 1: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis. Science 249: 146-151, 1990
-
(1990)
Science
, vol.249
, pp. 146-151
-
-
Weisman, H.F.1
Bartow, T.2
Leppo, M.K.3
Marsh, H.C.4
Carson, G.R.5
Concino, M.F.6
Boyle, M.P.7
Roux, K.H.8
Weisfeldt, M.L.9
Fearon, D.T.10
-
39
-
-
0032499629
-
Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: Role of the terminal complement components and inhibition by anti-C5 therapy
-
Vakeva AP, Agah A, Rollins SA, Matis LA, Li L, Stahl GL: Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inhibition by anti-C5 therapy. Circulation 97: 2259-2267, 1998
-
(1998)
Circulation
, vol.97
, pp. 2259-2267
-
-
Vakeva, A.P.1
Agah, A.2
Rollins, S.A.3
Matis, L.A.4
Li, L.5
Stahl, G.L.6
-
40
-
-
35948959015
-
Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria
-
Rother RP, Rollins SA, Mojcik CF, Brodsky RA, Bell L: Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria. Nat Biotechnol 25: 1256-1264, 2007
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1256-1264
-
-
Rother, R.P.1
Rollins, S.A.2
Mojcik, C.F.3
Brodsky, R.A.4
Bell, L.5
-
41
-
-
0037210289
-
Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3
-
Sahu A, Morikis D, Lambris JD: Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3. Mol Immunol 39: 557-566, 2003
-
(2003)
Mol Immunol
, vol.39
, pp. 557-566
-
-
Sahu, A.1
Morikis, D.2
Lambris, J.D.3
-
42
-
-
0029971956
-
Mouse complement component C4 is devoid of classical pathway C5 convertase subunit activity
-
Ebanks RO, Isenman DE: Mouse complement component C4 is devoid of classical pathway C5 convertase subunit activity. Mol Immunol 33: 297-309, 1996
-
(1996)
Mol Immunol
, vol.33
, pp. 297-309
-
-
Ebanks, R.O.1
Isenman, D.E.2
-
43
-
-
0035943638
-
A protein with characteristics of factor H is present on rodent platelets and functions as the immune adherence receptor
-
Alexander JJ, Hack BK, Cunningham PN, Quigg RJ: A protein with characteristics of factor H is present on rodent platelets and functions as the immune adherence receptor. J Biol Chem276: 32129-32135, 2001
-
(2001)
J Biol Chem276
, pp. 32129-32135
-
-
Alexander, J.J.1
Hack, B.K.2
Cunningham, P.N.3
Quigg, R.J.4
-
44
-
-
84863115476
-
Causes of alternative pathway dysregulation in dense deposit disease
-
Zhang Y, Meyer NC, Wang K, Nishimura C, Frees K, Jones M, Katz LM, Sethi S, Smith RJ: Causes of alternative pathway dysregulation in dense deposit disease. Clin J Am Soc Nephrol 7: 265-274, 2012
-
(2012)
Clin J am Soc Nephrol
, vol.7
, pp. 265-274
-
-
Zhang, Y.1
Meyer, N.C.2
Wang, K.3
Nishimura, C.4
Frees, K.5
Jones, M.6
Katz, L.M.7
Sethi, S.8
Smith, R.J.9
-
45
-
-
84864554927
-
Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
-
Servais A, Noël LH, Roumenina LT, Le Quintrec M, Ngo S, Dragon-Durey MA, Macher MA, Zuber J, Karras A, Provot F, Moulin B, Grünfeld JP, Niaudet P, Lesavre P, Frémeaux-Bacchi V: Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies. Kidney Int 82: 454-464, 2012
-
(2012)
Kidney Int
, vol.82
, pp. 454-464
-
-
Servais, A.1
Noël, L.H.2
Roumenina, L.T.3
Le Quintrec, M.4
Ngo, S.5
Dragon-Durey, M.A.6
Macher, M.A.7
Zuber, J.8
Karras, A.9
Provot, F.10
Moulin, B.11
Grünfeld, J.P.12
Niaudet, P.13
Lesavre, P.14
Frémeaux-Bacchi, V.15
-
46
-
-
70350279315
-
Atypical hemolytic-uremic syndrome
-
Noris M, Remuzzi G: Atypical hemolytic-uremic syndrome. N Engl J Med 361: 1676-1687, 2009
-
(2009)
N Engl J Med
, vol.361
, pp. 1676-1687
-
-
Noris, M.1
Remuzzi, G.2
-
47
-
-
84874610717
-
EuropeanWorking Party on Complement Genetics in Renal Diseases: Combined complement gene mutations in atypical hemolytic uremic syndrome influence clinical phenotype
-
Bresin E, Rurali E, Caprioli J, Sanchez-Corral P, Fremeaux-Bacchi V, Rodriguez de Cordoba S, Pinto S, Goodship TH, Alberti M, Ribes D, Valoti E, Remuzzi G, Noris M; EuropeanWorking Party on Complement Genetics in Renal Diseases: Combined complement gene mutations in atypical hemolytic uremic syndrome influence clinical phenotype. J Am Soc Nephrol 24: 475-486, 2013
-
(2013)
J am Soc Nephrol
, vol.24
, pp. 475-486
-
-
Bresin, E.1
Rurali, E.2
Caprioli, J.3
Sanchez-Corral, P.4
Fremeaux-Bacchi, V.5
Rodriguez De Cordoba, S.6
Pinto, S.7
Goodship, T.H.8
Alberti, M.9
Ribes, D.10
Valoti, E.11
Remuzzi, G.12
Noris, M.13
-
48
-
-
33750855444
-
Atypical haemolytic uraemic syndrome associated with a hybrid complement gene
-
Venables JP, Strain L, Routledge D, Bourn D, Powell HM, Warwicker P, Diaz-Torres ML, Sampson A, Mead P, Webb M, Pirson Y, Jackson MS, Hughes A, Wood KM, Goodship JA, Goodship TH: Atypical haemolytic uraemic syndrome associated with a hybrid complement gene. PLoS Med 3: e431, 2006
-
(2006)
Plos Med
, vol.3
-
-
Venables, J.P.1
Strain, L.2
Routledge, D.3
Bourn, D.4
Powell, H.M.5
Warwicker, P.6
Diaz-Torres, M.L.7
Sampson, A.8
Mead, P.9
Webb, M.10
Pirson, Y.11
Jackson, M.S.12
Hughes, A.13
Wood, K.M.14
Goodship, J.A.15
Goodship, T.H.16
-
49
-
-
79551489573
-
A novel deletion in the RCA gene cluster causes atypical hemolytic uremic syndrome
-
Maga TK, Meyer NC, Belsha C, Nishimura CJ, Zhang Y, Smith RJ: A novel deletion in the RCA gene cluster causes atypical hemolytic uremic syndrome. Nephrol Dial Transplant 26: 739-741, 2011
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 739-741
-
-
Maga, T.K.1
Meyer, N.C.2
Belsha, C.3
Nishimura, C.J.4
Zhang, Y.5
Smith, R.J.6
-
50
-
-
84885956193
-
A novel hybrid CFHR1/CFHgene causes atypical hemolytic uremic syndrome
-
Eyler SJ, Meyer NC, Zhang Y, Xiao X, Nester CM, Smith RJ: A novel hybrid CFHR1/CFHgene causes atypical hemolytic uremic syndrome. Pediatr Nephrol 28: 2221-2225, 2013
-
(2013)
Pediatr Nephrol
, vol.28
, pp. 2221-2225
-
-
Eyler, S.J.1
Meyer, N.C.2
Zhang, Y.3
Xiao, X.4
Nester, C.M.5
Smith, R.J.6
-
51
-
-
84924196365
-
A novel atypical hemolytic uremic syndrome-associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H-dependent complement regulation
-
Valoti E, Alberti M, Tortajada A, Garcia-Fernandez J, Gastoldi S, Besso L, Bresin E, Remuzzi G, Rodriguez de Cordoba S, Noris M: A novel atypical hemolytic uremic syndrome-associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H-dependent complement regulation. J Am Soc Nephrol 26: 209-219, 2015
-
(2015)
J am Soc Nephrol
, vol.26
, pp. 209-219
-
-
Valoti, E.1
Alberti, M.2
Tortajada, A.3
Garcia-Fernandez, J.4
Gastoldi, S.5
Besso, L.6
Bresin, E.7
Remuzzi, G.8
Rodriguez De Cordoba, S.9
Noris, M.10
-
52
-
-
84855862414
-
A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome
-
Francis NJ, McNicholas B, Awan A, Waldron M, Reddan D, Sadlier D, Kavanagh D, Strain L, Marchbank KJ, Harris CL, Goodship TH: A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome. Blood 119: 591-601, 2012
-
(2012)
Blood
, vol.119
, pp. 591-601
-
-
Francis, N.J.1
McNicholas, B.2
Awan, A.3
Waldron, M.4
Reddan, D.5
Sadlier, D.6
Kavanagh, D.7
Strain, L.8
Marchbank, K.J.9
Harris, C.L.10
Goodship, T.H.11
-
53
-
-
78649863686
-
Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome
-
Dragon-Durey MA, Sethi SK, Bagga A, Blanc C, Blouin J, Ranchin B, André JL, Takagi N, Cheong HI, Hari P, LeQuintrec M, Niaudet P, Loirat C, Fridman WH, Frémeaux-Bacchi V: Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome. J Am Soc Nephrol 21: 2180-2187, 2010
-
(2010)
J am Soc Nephrol
, vol.21
, pp. 2180-2187
-
-
Dragon-Durey, M.A.1
Sethi, S.K.2
Bagga, A.3
Blanc, C.4
Blouin, J.5
Ranchin, B.6
Ré, J.L.7
Takagi, N.8
Cheong, H.I.9
Hari, P.10
Lequintrec, M.11
Niaudet, P.12
Loirat, C.13
Fridman, W.H.14
Frémeaux-Bacchi, V.15
-
54
-
-
84864564017
-
C3 glomerulonephritis: Clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up
-
Sethi S, Fervenza FC, Zhang Y, Zand L, Vrana JA, Nasr SH, Theis JD, Dogan A, Smith RJ: C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up. Kidney Int 82: 465-473, 2012
-
(2012)
Kidney Int
, vol.82
, pp. 465-473
-
-
Sethi, S.1
Fervenza, F.C.2
Zhang, Y.3
Zand, L.4
Vrana, J.A.5
Nasr, S.H.6
Theis, J.D.7
Dogan, A.8
Smith, R.J.9
-
55
-
-
34147180032
-
Primary glomerulonephritis with isolated C3 deposits: A new entity which shares common genetic risk factors with haemolytic uraemic syndrome
-
Servais A, Frémeaux-Bacchi V, Lequintrec M, Salomon R, Blouin J, Knebelmann B, Grünfeld JP, Lesavre P, Noël LH, Fakhouri F: Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome. J Med Genet 44: 193-199, 2007
-
(2007)
J Med Genet
, vol.44
, pp. 193-199
-
-
Servais, A.1
Frémeaux-Bacchi, V.2
Lequintrec, M.3
Salomon, R.4
Blouin, J.5
Knebelmann, B.6
Grünfeld, J.P.7
Lesavre, P.8
Noël, L.H.9
Fakhouri, F.10
-
56
-
-
84878548121
-
C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation
-
Tortajada A, Yébenes H, Abarrategui-Garrido C, Anter J, García-Fernández JM, Martínez-Barricarte R, Alba-Domínguez M, Malik TH, Bedoya R, Cabrera Pérez R, López Trascasa M, Pickering MC, Harris CL, Sánchez-Corral P, Llorca O, Rodríguez de Córdoba S: C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation. J Clin Invest 123: 2434-2446, 2013
-
(2013)
J Clin Invest
, vol.123
, pp. 2434-2446
-
-
Tortajada, A.1
Yébenes, H.2
Abarrategui-Garrido, C.3
Anter, J.4
García-Fernández, J.M.5
Martínez-Barricarte, R.6
Alba-Domínguez, M.7
Malik, T.H.8
Bedoya, R.9
Cabrera Pérez, R.10
López Trascasa, M.11
Pickering, M.C.12
Harris, C.L.13
Sánchez-Corral, P.14
Llorca, O.15
Rodríguez De Córdoba, S.16
-
57
-
-
77957827919
-
Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation
-
Martínez-Barricarte R, Heurich M, Valdes-Cañedo F, Vazquez-Martul E, Torreira E, Montes T, Tortajada A, Pinto S, Lopez-Trascasa M, Morgan BP, Llorca O, Harris CL, Rodríguez de Córdoba S: Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. J Clin Invest 120: 3702-3712, 2010
-
(2010)
J Clin Invest
, vol.120
, pp. 3702-3712
-
-
Martínez-Barricarte, R.1
Heurich, M.2
Valdes-Cañedo, F.3
Vazquez-Martul, E.4
Torreira, E.5
Montes, T.6
Tortajada, A.7
Pinto, S.8
Lopez-Trascasa, M.9
Morgan, B.P.10
Llorca, O.11
Harris, C.L.12
Rodríguez De Córdoba, S.13
-
58
-
-
84947260202
-
For HUSI: An international consensus approach to the management of atypical hemolytic uremic syndrome in children
-
Loirat C, Fakhouri F, Ariceta G, Besbas N, Bitzan M, Bjerre A, Coppo R, Emma F, Johnson S, Karpman D, Landau D, Langman CB, Lapeyraque AL, Licht C, Nester C, Pecoraro C, Riedl M, van de Kar NC, Van deWalle J, Vivarelli M, Fremeaux-Bacchi V: for HUSI: An international consensus approach to the management of atypical hemolytic uremic syndrome in children. Pediatr Nephrol 31: 15-39, 2015
-
(2015)
Pediatr Nephrol
, vol.31
, pp. 15-39
-
-
Loirat, C.1
Fakhouri, F.2
Ariceta, G.3
Besbas, N.4
Bitzan, M.5
Bjerre, A.6
Coppo, R.7
Emma, F.8
Johnson, S.9
Karpman, D.10
Landau, D.11
Langman, C.B.12
Lapeyraque, A.L.13
Licht, C.14
Nester, C.15
Pecoraro, C.16
Riedl, M.17
Van De Kar, N.C.18
Van Dewalle, J.19
Vivarelli, M.20
Fremeaux-Bacchi, V.21
more..
-
59
-
-
0021684048
-
C3b covalently bound to IgG demonstrates a reduced rate of inactivation by factors H and I
-
Fries LF, Gaither TA, Hammer CH, Frank MM: C3b covalently bound to IgG demonstrates a reduced rate of inactivation by factors H and I. J Exp Med 160: 1640-1655, 1984
-
(1984)
J Exp Med
, vol.160
, pp. 1640-1655
-
-
Fries, L.F.1
Gaither, T.A.2
Hammer, C.H.3
Frank, M.M.4
-
60
-
-
0031884284
-
Immune complex glomerulonephritis in C4-and C3-deficient mice
-
Quigg RJ, Lim A, Haas M, Alexander JJ, He C, Carroll MC: Immune complex glomerulonephritis in C4-and C3-deficient mice. Kidney Int 53: 320-330, 1998
-
(1998)
Kidney Int
, vol.53
, pp. 320-330
-
-
Quigg, R.J.1
Lim, A.2
Haas, M.3
Alexander, J.J.4
He, C.5
Carroll, M.C.6
-
61
-
-
77958587405
-
Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
-
Noris M, Caprioli J, Bresin E, Mossali C, Pianetti G, Gamba S, Daina E, Fenili C, Castelletti F, Sorosina A, Piras R, Donadelli R, Maranta R, van der Meer I, Conway EM, Zipfel PF, Goodship TH, Remuzzi G: Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin J Am Soc Nephrol 5: 1844-1859, 2010
-
(2010)
Clin J am Soc Nephrol
, vol.5
, pp. 1844-1859
-
-
Noris, M.1
Caprioli, J.2
Bresin, E.3
Mossali, C.4
Pianetti, G.5
Gamba, S.6
Daina, E.7
Fenili, C.8
Castelletti, F.9
Sorosina, A.10
Piras, R.11
Donadelli, R.12
Maranta, R.13
Van Der Meer, I.14
Conway, E.M.15
Zipfel, P.F.16
Goodship, T.H.17
Remuzzi, G.18
-
62
-
-
84929518595
-
Complement Factor C4d Is a CommonDenominator in Thrombotic Microangiopathy
-
Chua JS, Baelde HJ, Zandbergen M, Wilhelmus S, van Es LA, de Fijter JW, Bruijn JA, Bajema IM, Cohen D: Complement Factor C4d Is a CommonDenominator in Thrombotic Microangiopathy. J Am Soc Nephrol 26: 2239-2247, 2015
-
(2015)
J am Soc Nephrol
, vol.26
, pp. 2239-2247
-
-
Chua, J.S.1
Baelde, H.J.2
Zandbergen, M.3
Wilhelmus, S.4
Van Es, L.A.5
De Fijter, J.W.6
Bruijn, J.A.7
Bajema, I.M.8
Cohen, D.9
-
63
-
-
84988443352
-
Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury
-
Laskowski J, Renner B, Le Quintrec M, Panzer S, Hannan JP, Ljubanovic D, Ruseva MM, Borza DB, Antonioli AH, Pickering MC, Holers VM, Thurman JM: Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury. Kidney Int 2016, in press
-
(2016)
Kidney Int
-
-
Laskowski, J.1
Renner, B.2
Le Quintrec, M.3
Panzer, S.4
Hannan, J.P.5
Ljubanovic, D.6
Ruseva, M.M.7
Borza, D.B.8
Antonioli, A.H.9
Pickering, M.C.10
Holers, V.M.11
Thurman, J.M.12
-
64
-
-
67649658244
-
M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy
-
Beck LH Jr, Bonegio RG, Lambeau G, Beck DM, Powell DW, Cummins TD, Klein JB, Salant DJ: M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 361: 11-21, 2009
-
(2009)
N Engl J Med
, vol.361
, pp. 11-21
-
-
Beck, L.H.1
Bonegio, R.G.2
Lambeau, G.3
Beck, D.M.4
Powell, D.W.5
Cummins, T.D.6
Klein, J.B.7
Salant, D.J.8
-
65
-
-
84918548245
-
Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy
-
Tomas NM, Beck LH Jr, Meyer-Schwesinger C, Seitz-Polski B, Ma H, Zahner G, Dolla G, Hoxha E, Helmchen U, Dabert-Gay AS, Debayle D, Merchant M, Klein J, Salant DJ, Stahl RA, Lambeau G: Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy. N Engl J Med 371: 2277-2287, 2014
-
(2014)
N Engl J Med
, vol.371
, pp. 2277-2287
-
-
Tomas, N.M.1
Beck, L.H.2
Meyer-Schwesinger, C.3
Seitz-Polski, B.4
Ma, H.5
Zahner, G.6
Dolla, G.7
Hoxha, E.8
Helmchen, U.9
Dabert-Gay, A.S.10
Debayle, D.11
Merchant, M.12
Klein, J.13
Salant, D.J.14
Stahl, R.A.15
Lambeau, G.16
-
66
-
-
0029799580
-
CR1 stump peptide and terminal complement complexes are found in the glomeruli of lupus nephritis patients
-
Teixeira JE, Costa RS, Lachmann PJ, Würzner R, Barbosa JE: CR1 stump peptide and terminal complement complexes are found in the glomeruli of lupus nephritis patients. Clin Exp Immunol 105: 497-503, 1996
-
(1996)
Clin Exp Immunol
, vol.105
, pp. 497-503
-
-
Teixeira, J.E.1
Costa, R.S.2
Lachmann, P.J.3
Würzner, R.4
Barbosa, J.E.5
-
67
-
-
84905920413
-
Newinsights into the pathogenesis of IgA nephropathy
-
Floege J, Moura IC, Daha MR: Newinsights into the pathogenesis of IgA nephropathy. Semin Immunopathol 36: 431-442, 2014
-
(2014)
Semin Immunopathol
, vol.36
, pp. 431-442
-
-
Floege, J.1
Moura, I.C.2
Daha, M.R.3
-
68
-
-
84934766063
-
Current Understanding of the Role of Complement in IgA Nephropathy
-
Maillard N, Wyatt RJ, Julian BA, Kiryluk K, Gharavi A, Fremeaux-Bacchi V, Novak J: Current Understanding of the Role of Complement in IgA Nephropathy. J Am Soc Nephrol 26: 1503-1512, 2015
-
(2015)
J am Soc Nephrol
, vol.26
, pp. 1503-1512
-
-
Maillard, N.1
Wyatt, R.J.2
Julian, B.A.3
Kiryluk, K.4
Gharavi, A.5
Fremeaux-Bacchi, V.6
Novak, J.7
-
69
-
-
79953224410
-
Genomewide association study identifies susceptibility loci for IgA nephropathy
-
Gharavi AG, Kiryluk K, Choi M, Li Y, Hou P, Xie J, Sanna-Cherchi S, Men CJ, Julian BA, Wyatt RJ, Novak J, He JC, Wang H, Lv J, Zhu L, Wang W, Wang Z, Yasuno K, Gunel M, Mane S, Umlauf S, Tikhonova I, Beerman I, Savoldi S, Magistroni R, Ghiggeri GM, Bodria M, Lugani F, Ravani P, Ponticelli C, Allegri L, Boscutti G, Frasca G, Amore A, Peruzzi L, Coppo R, Izzi C, Viola BF, Prati E, Salvadori M, Mignani R, Gesualdo L, Bertinetto F, Mesiano P, Amoroso A, Scolari F, Chen N, Zhang H, Lifton RP: Genomewide association study identifies susceptibility loci for IgA nephropathy. Nat Genet 43: 321-327, 2011
-
(2011)
Nat Genet
, vol.43
, pp. 321-327
-
-
Gharavi, A.G.1
Kiryluk, K.2
Choi, M.3
Li, Y.4
Hou, P.5
Xie, J.6
Sanna-Cherchi, S.7
Men, C.J.8
Julian, B.A.9
Wyatt, R.J.10
Novak, J.11
He, J.C.12
Wang, H.13
Lv, J.14
Zhu, L.15
Wang, W.16
Wang, Z.17
Yasuno, K.18
Gunel, M.19
Mane, S.20
Umlauf, S.21
Tikhonova, I.22
Beerman, I.23
Savoldi, S.24
Magistroni, R.25
Ghiggeri, G.M.26
Bodria, M.27
Lugani, F.28
Ravani, P.29
Ponticelli, C.30
Allegri, L.31
Boscutti, G.32
Frasca, G.33
Amore, A.34
Peruzzi, L.35
Coppo, R.36
Izzi, C.37
Viola, B.F.38
Prati, E.39
Salvadori, M.40
Mignani, R.41
Gesualdo, L.42
Bertinetto, F.43
Mesiano, P.44
Amoroso, A.45
Scolari, F.46
Chen, N.47
Zhang, H.48
Lifton, R.P.49
more..
-
70
-
-
84999762007
-
Rare Variants in the Complement Factor HRelated Protein 5 Gene Contribute to Genetic Susceptibility to IgA Nephropathy [published online ahead of print January 29, 2016]
-
Zhai YL, Meng SJ, Zhu L, Shi SF, Wang SX, Liu LJ, Lv JC, Yu F, Zhao MH, Zhang H: Rare Variants in the Complement Factor HRelated Protein 5 Gene Contribute to Genetic Susceptibility to IgA Nephropathy [published online ahead of print January 29, 2016]. J Am Soc Nephrol doi:10.1681/ASN.2015010012
-
J am Soc Nephrol
-
-
Zhai, Y.L.1
Meng, S.J.2
Zhu, L.3
Shi, S.F.4
Wang, S.X.5
Liu, L.J.6
Lv, J.C.7
Yu, F.8
Zhao, M.H.9
Zhang, H.10
-
71
-
-
0013443651
-
Chronic progression of tubulointerstitial damage in proteinuric renal disease is mediated by complement activation: A therapeutic role for complement inhibitors?
-
Hsu SI, Couser WG: Chronic progression of tubulointerstitial damage in proteinuric renal disease is mediated by complement activation: a therapeutic role for complement inhibitors? J Am Soc Nephrol 14[Suppl 2]: S186-S191, 2003
-
(2003)
J am Soc Nephrol
, vol.14
, pp. S186-S191
-
-
Hsu, S.I.1
Couser, W.G.2
-
72
-
-
42049109282
-
Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury
-
Sheerin NS, Risley P, Abe K, Tang Z, Wong W, Lin T, Sacks SH: Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J 22: 1065-1072, 2008
-
(2008)
FASEB J
, vol.22
, pp. 1065-1072
-
-
Sheerin, N.S.1
Risley, P.2
Abe, K.3
Tang, Z.4
Wong, W.5
Lin, T.6
Sacks, S.H.7
-
73
-
-
0021886145
-
Pathophysiology of chronic tubulo-interstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3
-
Nath KA, Hostetter MK, Hostetter TH: Pathophysiology of chronic tubulo-interstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3. J Clin Invest 76: 667-675, 1985
-
(1985)
J Clin Invest
, vol.76
, pp. 667-675
-
-
Nath, K.A.1
Hostetter, M.K.2
Hostetter, T.H.3
-
74
-
-
84876044818
-
Genetics and outcome of atypical hemolytic uremic syndrome: A nationwide French series comparing children and adults
-
Fremeaux-Bacchi V, Fakhouri F, Garnier A, Bienaimé F, Dragon-Durey MA, Ngo S, Moulin B, Servais A, Provot F, Rostaing L, Burtey S, Niaudet P, Deschênes G, Lebranchu Y, Zuber J, Loirat C: Genetics and outcome of atypical hemolytic uremic syndrome: a nationwide French series comparing children and adults. Clin J Am Soc Nephrol 8: 554-562, 2013
-
(2013)
Clin J am Soc Nephrol
, vol.8
, pp. 554-562
-
-
Fremeaux-Bacchi, V.1
Fakhouri, F.2
Garnier, A.3
Bienaimé, F.4
Dragon-Durey, M.A.5
Ngo, S.6
Moulin, B.7
Servais, A.8
Provot, F.9
Rostaing, L.10
Burtey, S.11
Niaudet, P.12
Deschênes, G.13
Lebranchu, Y.14
Zuber, J.15
Loirat, C.16
-
75
-
-
84927156913
-
The major autoantibody epitope on factorH in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease
-
Bhattacharjee A, Reuter S, Trojnár E, Kolodziejczyk R, Seeberger H, Hyvärinen S, Uzonyi B, Szilágyi Á, Prohászka Z, Goldman A, Józsi M, Jokiranta TS: The major autoantibody epitope on factorH in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease. J Biol Chem 290: 9500-9510, 2015
-
(2015)
J Biol Chem
, vol.290
, pp. 9500-9510
-
-
Bhattacharjee, A.1
Reuter, S.2
Trojnár, E.3
Kolodziejczyk, R.4
Seeberger, H.5
Hyvärinen, S.6
Uzonyi, B.7
Szilágyi, Á.8
Prohászka, Z.9
Goldman, A.10
Józsi, M.11
Jokiranta, T.S.12
-
76
-
-
34250329129
-
Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
-
Pickering MC, de Jorge EG, Martinez-Barricarte R, Recalde S, Garcia-Layana A, Rose KL, Moss J, Walport MJ, Cook HT, de Córdoba SR, Botto M: Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains. J Exp Med 204: 1249-1256, 2007
-
(2007)
J Exp Med
, vol.204
, pp. 1249-1256
-
-
Pickering, M.C.1
De Jorge, E.G.2
Martinez-Barricarte, R.3
Recalde, S.4
Garcia-Layana, A.5
Rose, K.L.6
Moss, J.7
Walport, M.J.8
Cook, H.T.9
De Córdoba, S.R.10
Botto, M.11
-
77
-
-
84878589219
-
Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome
-
Legendre CM, Licht C, Muus P, Greenbaum LA, Babu S, Bedrosian C, Bingham C, Cohen DJ, Delmas Y, Douglas K, Eitner F, Feldkamp T, Fouque D, Furman RR, Gaber O, Herthelius M, Hourmant M, Karpman D, Lebranchu Y, Mariat C, Menne J, Moulin B, Nürnberger J, Ogawa M, Remuzzi G, Richard T, Sberro-Soussan R, Severino B, Sheerin NS, Trivelli A, Zimmerhackl LB, Goodship T, Loirat C: Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med 368: 2169-2181, 2013
-
(2013)
N Engl J Med
, vol.368
, pp. 2169-2181
-
-
Legendre, C.M.1
Licht, C.2
Muus, P.3
Greenbaum, L.A.4
Babu, S.5
Bedrosian, C.6
Bingham, C.7
Cohen, D.J.8
Delmas, Y.9
Douglas, K.10
Eitner, F.11
Feldkamp, T.12
Fouque, D.13
Furman, R.R.14
Gaber, O.15
Herthelius, M.16
Hourmant, M.17
Karpman, D.18
Lebranchu, Y.19
Mariat, C.20
Menne, J.21
Moulin, B.22
Nürnberger, J.23
Ogawa, M.24
Remuzzi, G.25
Richard, T.26
Sberro-Soussan, R.27
Severino, B.28
Sheerin, N.S.29
Trivelli, A.30
Zimmerhackl, L.B.31
Goodship, T.32
Loirat, C.33
more..
-
78
-
-
84964561130
-
Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome
-
Greenbaum LA, Fila M, Ardissino G, Al-Akash SI, Evans J, Henning P, Lieberman KV, Maringhini S, Pape L, Rees L, van de Kar NC, VandeWalle J, Ogawa M, Bedrosian CL, Licht C: Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome. Kidney Int 89: 701-711, 2016
-
(2016)
Kidney Int
, vol.89
, pp. 701-711
-
-
Greenbaum, L.A.1
Fila, M.2
Ardissino, G.3
Al-Akash, S.I.4
Evans, J.5
Henning, P.6
Lieberman, K.V.7
Maringhini, S.8
Pape, L.9
Rees, L.10
Van De Kar, N.C.11
Vandewalle, J.12
Ogawa, M.13
Bedrosian, C.L.14
Licht, C.15
-
79
-
-
84893799889
-
Genetic variants in C5 and poor response to eculizumab
-
Nishimura J, Yamamoto M, Hayashi S, Ohyashiki K, Ando K, Brodsky AL, Noji H, Kitamura K, Eto T, Takahashi T, Masuko M, Matsumoto T, Wano Y, Shichishima T, Shibayama H, Hase M, Li L, Johnson K, Lazarowski A, Tamburini P, Inazawa J, Kinoshita T, Kanakura Y: Genetic variants in C5 and poor response to eculizumab. N Engl J Med 370: 632-639, 2014
-
(2014)
N Engl J Med
, vol.370
, pp. 632-639
-
-
Nishimura, J.1
Yamamoto, M.2
Hayashi, S.3
Ohyashiki, K.4
Ando, K.5
Brodsky, A.L.6
Noji, H.7
Kitamura, K.8
Eto, T.9
Takahashi, T.10
Masuko, M.11
Matsumoto, T.12
Wano, Y.13
Shichishima, T.14
Shibayama, H.15
Hase, M.16
Li, L.17
Johnson, K.18
Lazarowski, A.19
Tamburini, P.20
Inazawa, J.21
Kinoshita, T.22
Kanakura, Y.23
more..
-
80
-
-
84870534251
-
Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation
-
Zuber J, Quintrec ML, Krid S, Bertoye C, Gueutin V, Lahoche A, Heyne N, Ardissino G, Chatelet V, Noel LH, Hourmant M, Niaudet P, Frémeaux-Bacchi V, Rondeau E, Legendre C, Loirat C: Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation. Am J Transplant 12: 3337-3354, 2012
-
(2012)
Am J Transplant
, vol.12
, pp. 3337-3354
-
-
Zuber, J.1
Quintrec, M.L.2
Krid, S.3
Bertoye, C.4
Gueutin, V.5
Lahoche, A.6
Heyne, N.7
Ardissino, G.8
Chatelet, V.9
Noel, L.H.10
Hourmant, M.11
Niaudet, P.12
Frémeaux-Bacchi, V.13
Rondeau, E.14
Legendre, C.15
Loirat, C.16
-
81
-
-
62149135267
-
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy
-
Tang Z, Lu B, Hatch E, Sacks SH, Sheerin NS: C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol 20: 593-603, 2009
-
(2009)
J am Soc Nephrol
, vol.20
, pp. 593-603
-
-
Tang, Z.1
Lu, B.2
Hatch, E.3
Sacks, S.H.4
Sheerin, N.S.5
-
82
-
-
38849102544
-
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice
-
Rose KL, Paixao-Cavalcante D, Fish J, Manderson AP, Malik TH, Bygrave AE, Lin T, Sacks SH, Walport MJ, Cook HT, Botto M, Pickering MC: Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest 118: 608-618, 2008
-
(2008)
J Clin Invest
, vol.118
, pp. 608-618
-
-
Rose, K.L.1
Paixao-Cavalcante, D.2
Fish, J.3
Manderson, A.P.4
Malik, T.H.5
Bygrave, A.E.6
Lin, T.7
Sacks, S.H.8
Walport, M.J.9
Cook, H.T.10
Botto, M.11
Pickering, M.C.12
-
83
-
-
84936985706
-
Atypical aHUS: State of the art
-
Nester CM, Barbour T, de Cordoba SR, Dragon-Durey MA, Fremeaux-Bacchi V, Goodship TH, Kavanagh D, Noris M, Pickering M, Sanchez-Corral P, Skerka C, Zipfel P, Smith RJ: Atypical aHUS: State of the art. Mol Immunol 67: 31-42, 2015
-
(2015)
Mol Immunol
, vol.67
, pp. 31-42
-
-
Nester, C.M.1
Barbour, T.2
De Cordoba, S.R.3
Dragon-Durey, M.A.4
Fremeaux-Bacchi, V.5
Goodship, T.H.6
Kavanagh, D.7
Noris, M.8
Pickering, M.9
Sanchez-Corral, P.10
Skerka, C.11
Zipfel, P.12
Smith, R.J.13
-
84
-
-
77952556624
-
Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations
-
Fakhouri F, Roumenina L, Provot F, Sallée M, Caillard S, Couzi L, Essig M, Ribes D, Dragon-Durey MA, Bridoux F, Rondeau E, Frémeaux-Bacchi V: Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J Am Soc Nephrol 21: 859-867, 2010
-
(2010)
J am Soc Nephrol
, vol.21
, pp. 859-867
-
-
Fakhouri, F.1
Roumenina, L.2
Provot, F.3
Sallée, M.4
Caillard, S.5
Couzi, L.6
Essig, M.7
Ribes, D.8
Dragon-Durey, M.A.9
Bridoux, F.10
Rondeau, E.11
Frémeaux-Bacchi, V.12
-
85
-
-
84902254536
-
Treatment of C3 glomerulopathy with complement blockers
-
Vivarelli M, Emma F: Treatment of C3 glomerulopathy with complement blockers. Semin Thromb Hemost 40: 472-477, 2014
-
(2014)
Semin Thromb Hemost
, vol.40
, pp. 472-477
-
-
Vivarelli, M.1
Emma, F.2
-
86
-
-
84864485595
-
Brief report: Induction of sustained remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab
-
Shapira I, Andrade D, Allen SL, Salmon JE: Brief report: induction of sustained remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab. Arthritis Rheum 64: 2719-2723, 2012
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2719-2723
-
-
Shapira, I.1
Rade, D.2
Allen, S.L.3
Salmon, J.E.4
-
87
-
-
84983094382
-
Eculizumab as rescue therapy in severe resistant lupus nephritis
-
Pickering MC, Ismajli M, Condon MB, McKenna N, Hall AE, Lightstone L, Terence Cook H, Cairns TD: Eculizumab as rescue therapy in severe resistant lupus nephritis. Rheumatology (Oxford) 54: 2286-2288, 2015
-
(2015)
Rheumatology (Oxford)
, vol.54
, pp. 2286-2288
-
-
Pickering, M.C.1
Ismajli, M.2
Condon, M.B.3
McKenna, N.4
Hall, A.E.5
Lightstone, L.6
Terence Cook, H.7
Cairns, T.D.8
-
88
-
-
84930703194
-
Eculizumab treatment for rescue of renal function in IgA nephropathy
-
Rosenblad T, Rebetz J, Johansson M, Békássy Z, Sartz L, Karpman D: Eculizumab treatment for rescue of renal function in IgA nephropathy. Pediatr Nephrol 29: 2225-2228, 2014
-
(2014)
Pediatr Nephrol
, vol.29
, pp. 2225-2228
-
-
Rosenblad, T.1
Rebetz, J.2
Johansson, M.3
Békássy, Z.4
Sartz, L.5
Karpman, D.6
-
89
-
-
84875990477
-
Complement in immune and inflammatory disorders: Therapeutic interventions
-
Ricklin D, Lambris JD: Complement in immune and inflammatory disorders: therapeutic interventions. J Immunol 190: 3839-3847, 2013
-
(2013)
J Immunol
, vol.190
, pp. 3839-3847
-
-
Ricklin, D.1
Lambris, J.D.2
-
90
-
-
84893502246
-
C5a receptor (CD88) blockade protects against MPO-ANCA GN
-
Xiao H, Dairaghi DJ, Powers JP, Ertl LS, Baumgart T, Wang Y, Seitz LC, Penfold ME, Gan L, Hu P, Lu B, Gerard NP, Gerard C, Schall TJ, Jaen JC, Falk RJ, Jennette JC: C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol 25: 225-231, 2014
-
(2014)
J am Soc Nephrol
, vol.25
, pp. 225-231
-
-
Xiao, H.1
Dairaghi, D.J.2
Powers, J.P.3
Ertl, L.S.4
Baumgart, T.5
Wang, Y.6
Seitz, L.C.7
Penfold, M.E.8
Gan, L.9
Hu, P.10
Lu, B.11
Gerard, N.P.12
Gerard, C.13
Schall, T.J.14
Jaen, J.C.15
Falk, R.J.16
Jennette, J.C.17
-
91
-
-
84977495983
-
Targeting the Complement Cascade: Novel Treatments Coming down the Pike
-
Thurman JM, Le Quintrec M: Targeting the Complement Cascade: Novel Treatments Coming down the Pike. Kidney Int 2016, in press
-
(2016)
Kidney Int
-
-
Thurman, J.M.1
Le Quintrec, M.2
-
92
-
-
79960452978
-
Complement deficiency states and associated infections
-
Skattum L, van Deuren M, van der Poll T, Truedsson L: Complement deficiency states and associated infections. Mol Immunol 48: 1643-1655, 2011
-
(2011)
Mol Immunol
, vol.48
, pp. 1643-1655
-
-
Skattum, L.1
Van Deuren, M.2
Van Der Poll, T.3
Truedsson, L.4
-
93
-
-
79958849218
-
Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: Sustained efficacy and improved survival
-
Kelly RJ, Hill A, Arnold LM, Brooksbank GL, Richards SJ, Cullen M, Mitchell LD, Cohen DR, Gregory WM, Hillmen P: Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival. Blood 117: 6786-6792, 2011
-
(2011)
Blood
, vol.117
, pp. 6786-6792
-
-
Kelly, R.J.1
Hill, A.2
Arnold, L.M.3
Brooksbank, G.L.4
Richards, S.J.5
Cullen, M.6
Mitchell, L.D.7
Cohen, D.R.8
Gregory, W.M.9
Hillmen, P.10
-
94
-
-
84908611206
-
Dynamics of complement activation in aHUS and how to monitor eculizumab therapy
-
Noris M, Galbusera M, Gastoldi S, Macor P, Banterla F, Bresin E, Tripodo C, Bettoni S, Donadelli R, Valoti E, Tedesco F, Amore A, Coppo R, Ruggenenti P, Gotti E, Remuzzi G: Dynamics of complement activation in aHUS and how to monitor eculizumab therapy. Blood 124: 1715-1726, 2014
-
(2014)
Blood
, vol.124
, pp. 1715-1726
-
-
Noris, M.1
Galbusera, M.2
Gastoldi, S.3
Macor, P.4
Banterla, F.5
Bresin, E.6
Tripodo, C.7
Bettoni, S.8
Donadelli, R.9
Valoti, E.10
Tedesco, F.11
Amore, A.12
Coppo, R.13
Ruggenenti, P.14
Gotti, E.15
Remuzzi, G.16
-
95
-
-
2442693874
-
Immune complex deposits in ANCAassociated crescentic glomerulonephritis: A study of 126 cases
-
Haas M, Eustace JA: Immune complex deposits in ANCAassociated crescentic glomerulonephritis: a study of 126 cases. Kidney Int 65: 2145-2152, 2004
-
(2004)
Kidney Int
, vol.65
, pp. 2145-2152
-
-
Haas, M.1
Eustace, J.A.2
|