-
2
-
-
0036533640
-
Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice
-
Bao L, Haas M, Boackle SA, Kraus DM, Cunningham PN, Park P, Alexander JJ, Anderson RK, Culhane K, Holers VM, Quigg RJ. Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice. J Immunol 168: 3601-3607, 2002.
-
(2002)
J Immunol
, vol.168
, pp. 3601-3607
-
-
Bao, L.1
Haas, M.2
Boackle, S.A.3
Kraus, D.M.4
Cunningham, P.N.5
Park, P.6
Alexander, J.J.7
Anderson, R.K.8
Culhane, K.9
Holers, V.M.10
Quigg, R.J.11
-
3
-
-
0028055096
-
Alternative pathway activation of complement by cultured human proximal tubular epithelial cells
-
Biancone L, David S, Della Pietra V, Montrucchio G, Cambi V, Camussi G. Alternative pathway activation of complement by cultured human proximal tubular epithelial cells. Kidney Int 45: 451-460, 1994.
-
(1994)
Kidney Int
, vol.45
, pp. 451-460
-
-
Biancone, L.1
David, S.2
Della Pietra, V.3
Montrucchio, G.4
Cambi, V.5
Camussi, G.6
-
4
-
-
0019786317
-
Renal localization of the membrane attack complex in systemic lupus erythematosus nephritis
-
Biesecker G, Katz S, Koffler D. Renal localization of the membrane attack complex in systemic lupus erythematosus nephritis. J Exp Med 154: 1779-1794, 1981.
-
(1981)
J Exp Med
, vol.154
, pp. 1779-1794
-
-
Biesecker, G.1
Katz, S.2
Koffler, D.3
-
5
-
-
0023583181
-
Significance of tubulointerstitial changes in the renal cortex for the excretory function and concentration ability of the kidney: A morphometric contribution
-
Bohle A, Mackensen-Haen S, von Gise H. Significance of tubulointerstitial changes in the renal cortex for the excretory function and concentration ability of the kidney: a morphometric contribution. Am J Nephrol 7: 421-433, 1987.
-
(1987)
Am J Nephrol
, vol.7
, pp. 421-433
-
-
Bohle, A.1
Mackensen-Haen, S.2
von Gise, H.3
-
6
-
-
0028349782
-
Pathogenesis of chronic renal failure in primary glomerulopathies
-
Bohle A, Wehrmann M, Mackensen-Haen S, Gise H, Mickeler E, Xiao TC, Muller C, Muller GA. Pathogenesis of chronic renal failure in primary glomerulopathies. Nephrol Dial Transplant 9, Suppl 3: 4-12, 1994.
-
(1994)
Nephrol Dial Transplant
, vol.9
, Issue.SUPPL. 3
, pp. 4-12
-
-
Bohle, A.1
Wehrmann, M.2
Mackensen-Haen, S.3
Gise, H.4
Mickeler, E.5
Xiao, T.C.6
Muller, C.7
Muller, G.A.8
-
7
-
-
0020041602
-
In vitro alternative pathway activation of complement by the brush border of proximal tubules of normal rat kidney
-
Camussi G, Rotunno M, Segoloni G, Brentjens JR, Andres GA. In vitro alternative pathway activation of complement by the brush border of proximal tubules of normal rat kidney. J Immunol 128: 1659-1663, 1982.
-
(1982)
J Immunol
, vol.128
, pp. 1659-1663
-
-
Camussi, G.1
Rotunno, M.2
Segoloni, G.3
Brentjens, J.R.4
Andres, G.A.5
-
8
-
-
0021888927
-
In vivo localization of C3 on the brush border of proximal tubules of kidneys from nephrotic patients
-
Camussi G, Stratta P, Mazzucco G, Gaido M, Tetta C, Castello R, Rotunno M, Vercellone A. In vivo localization of C3 on the brush border of proximal tubules of kidneys from nephrotic patients. Clin Nephrol 23: 134-141, 1985.
-
(1985)
Clin Nephrol
, vol.23
, pp. 134-141
-
-
Camussi, G.1
Stratta, P.2
Mazzucco, G.3
Gaido, M.4
Tetta, C.5
Castello, R.6
Rotunno, M.7
Vercellone, A.8
-
9
-
-
0035889946
-
Epitope mapping using the X-ray crystallographic structure of complement receptor type 2 (CR2)/CD21: Identification of a highly inhibitory monoclonal antibody that directly recognizes the CR2-C3d interface
-
Guthridge JM, Young K, Gipson MG, Sarrias MR, Szakonyi G, Chen XS, Malaspina A, Donoghue E, James JA, Lambris JD, Moir SA, Perkins SJ, Holers VM. Epitope mapping using the X-ray crystallographic structure of complement receptor type 2 (CR2)/CD21: identification of a highly inhibitory monoclonal antibody that directly recognizes the CR2-C3d interface. J Immunol 167: 5758 -5766, 2001.
-
(2001)
J Immunol
, vol.167
, pp. 5758-5766
-
-
Guthridge, J.M.1
Young, K.2
Gipson, M.G.3
Sarrias, M.R.4
Szakonyi, G.5
Chen, X.S.6
Malaspina, A.7
Donoghue, E.8
James, J.A.9
Lambris, J.D.10
Moir, S.A.11
Perkins, S.J.12
Holers, V.M.13
-
10
-
-
0033405957
-
-
Hori Y, Yamada K, Hanafusa N, Okuda T, Okada N, Miyata T, Couser WG, Kurokawa K, Fujita T, Nangaku M. Crry, a complement regulatory protein, modulates renal interstitial disease induced by proteinuria. Kidney Int 56: 2096-2106, 1999.
-
Hori Y, Yamada K, Hanafusa N, Okuda T, Okada N, Miyata T, Couser WG, Kurokawa K, Fujita T, Nangaku M. Crry, a complement regulatory protein, modulates renal interstitial disease induced by proteinuria. Kidney Int 56: 2096-2106, 1999.
-
-
-
-
11
-
-
0013443651
-
Chronic progression of tubulointerstitial damage in proteinuric renal disease is mediated by complement activation: A therapeutic role for complement inhibitors?
-
Hsu SI, Couser WG. Chronic progression of tubulointerstitial damage in proteinuric renal disease is mediated by complement activation: a therapeutic role for complement inhibitors? J Am Soc Nephrol 14: S186-S191, 2003.
-
(2003)
J Am Soc Nephrol
, vol.14
-
-
Hsu, S.I.1
Couser, W.G.2
-
12
-
-
0028239796
-
Localization of the complement regulatory proteins in the normal human kidney
-
Ichida S, Yuzawa Y, Okada H, Yoshioka K, Matsuo S. Localization of the complement regulatory proteins in the normal human kidney. Kidney Int 46: 89-96, 1994.
-
(1994)
Kidney Int
, vol.46
, pp. 89-96
-
-
Ichida, S.1
Yuzawa, Y.2
Okada, H.3
Yoshioka, K.4
Matsuo, S.5
-
13
-
-
0028364426
-
Tubular catabolism of albumin is associated with the release of an inflammatory lipid
-
Kees-Folts D, Sadow JL, Schreiner GF. Tubular catabolism of albumin is associated with the release of an inflammatory lipid. Kidney Int 45: 1697-1709, 1994.
-
(1994)
Kidney Int
, vol.45
, pp. 1697-1709
-
-
Kees-Folts, D.1
Sadow, J.L.2
Schreiner, G.F.3
-
14
-
-
0030058570
-
Control of the complement system
-
Liszewski MK, Farries TC, Lublin DM, Rooney IA, Atkinson JP. Control of the complement system. Adv Immunol 61: 201-283, 1996.
-
(1996)
Adv Immunol
, vol.61
, pp. 201-283
-
-
Liszewski, M.K.1
Farries, T.C.2
Lublin, D.M.3
Rooney, I.A.4
Atkinson, J.P.5
-
15
-
-
0019432032
-
Correlations between renal cortical interstitial fibrosis, atrophy of the proximal tubules and impairment of the glomerular filtration rate
-
Mackensen-Haen S, Bader R, Grund KE, Bohle A. Correlations between renal cortical interstitial fibrosis, atrophy of the proximal tubules and impairment of the glomerular filtration rate. Clin Nephrol 15: 167-171, 1981.
-
(1981)
Clin Nephrol
, vol.15
, pp. 167-171
-
-
Mackensen-Haen, S.1
Bader, R.2
Grund, K.E.3
Bohle, A.4
-
16
-
-
12644280801
-
Abrogation of the alternative complement pathway by targeted deletion of murine factor B
-
Matsumoto M, Fukuda W, Circolo A, Goellner J, Strauss-Schoenberger J, Wang X, Fujita S, Hidvegi T, Chaplin DD, Colten HR. Abrogation of the alternative complement pathway by targeted deletion of murine factor B. Proc Natl Acad Sci USA 94: 8720-8725, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8720-8725
-
-
Matsumoto, M.1
Fukuda, W.2
Circolo, A.3
Goellner, J.4
Strauss-Schoenberger, J.5
Wang, X.6
Fujita, S.7
Hidvegi, T.8
Chaplin, D.D.9
Colten, H.R.10
-
17
-
-
0034068043
-
Complement activation products in the urine from proteinuric patients
-
Morita Y, Ikeguchi H, Nakamura J, Hotta N, Yuzawa Y, Matsuo S. Complement activation products in the urine from proteinuric patients. J Am Soc Nephrol 11: 700-707, 2000.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 700-707
-
-
Morita, Y.1
Ikeguchi, H.2
Nakamura, J.3
Hotta, N.4
Yuzawa, Y.5
Matsuo, S.6
-
18
-
-
0032711255
-
Complement membrane attack complex (C5b-9) mediates interstitial disease in experimental nephrotic syndrome
-
Nangaku M, Pippin J, Couser WG. Complement membrane attack complex (C5b-9) mediates interstitial disease in experimental nephrotic syndrome. J Am Soc Nephrol 10: 2323-2331, 1999.
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 2323-2331
-
-
Nangaku, M.1
Pippin, J.2
Couser, W.G.3
-
19
-
-
0036209624
-
C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys
-
Nangaku M, Pippin J, Couser WG. C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys. J Am Soc Nephrol 13: 928-936, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 928-936
-
-
Nangaku, M.1
Pippin, J.2
Couser, W.G.3
-
20
-
-
0026769228
-
Tubulointerstitial changes as a major determinant in the progression of renal damage
-
Nath KA. Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kidney Dis 20: 1-17, 1992.
-
(1992)
Am J Kidney Dis
, vol.20
, pp. 1-17
-
-
Nath, K.A.1
-
21
-
-
0025799751
-
Increased ammoniagenesis as a determinant of progressive renal injury
-
Nath KA, Hostetter MK, Hostetter TH. Increased ammoniagenesis as a determinant of progressive renal injury. Am J Kidney Dis 17: 654-657, 1991.
-
(1991)
Am J Kidney Dis
, vol.17
, pp. 654-657
-
-
Nath, K.A.1
Hostetter, M.K.2
Hostetter, T.H.3
-
22
-
-
0030857577
-
Role of complement in acute tubulointerstitial injury of rats with aminonucleoside nephrosis
-
Nomura A, Morita Y, Maruyama S, Hotta N, Nadai M, Wang L, Hasegawa T, Matsuo S. Role of complement in acute tubulointerstitial injury of rats with aminonucleoside nephrosis. Am J Pathol 151: 539-547, 1997.
-
(1997)
Am J Pathol
, vol.151
, pp. 539-547
-
-
Nomura, A.1
Morita, Y.2
Maruyama, S.3
Hotta, N.4
Nadai, M.5
Wang, L.6
Hasegawa, T.7
Matsuo, S.8
-
23
-
-
0036092207
-
The effect of pH and nucleophiles on complement activation by human proximal tubular epithelial cells
-
Peake PW, Pussell BA, Mackinnon B, Charlesworth JA. The effect of pH and nucleophiles on complement activation by human proximal tubular epithelial cells. Nephrol Dial Transplant 17: 745-752, 2002.
-
(2002)
Nephrol Dial Transplant
, vol.17
, pp. 745-752
-
-
Peake, P.W.1
Pussell, B.A.2
Mackinnon, B.3
Charlesworth, J.A.4
-
24
-
-
0032487432
-
Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury
-
Quigg RJ, He C, Lim A, Berthiaume D, Alexander JJ, Kraus D, Holers VM. Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury. J Exp Med 188: 1321-1331, 1998.
-
(1998)
J Exp Med
, vol.188
, pp. 1321-1331
-
-
Quigg, R.J.1
He, C.2
Lim, A.3
Berthiaume, D.4
Alexander, J.J.5
Kraus, D.6
Holers, V.M.7
-
25
-
-
12344262720
-
C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria
-
Rangan GK, Pippin JW, Coombes JD, Couser WG. C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria. Kidney Int 67: 492-503, 2005.
-
(2005)
Kidney Int
, vol.67
, pp. 492-503
-
-
Rangan, G.K.1
Pippin, J.W.2
Coombes, J.D.3
Couser, W.G.4
-
26
-
-
0033659112
-
A unifying hypothesis for renal scarring linking protein trafficking to the different mediators of injury
-
Remuzzi G. A unifying hypothesis for renal scarring linking protein trafficking to the different mediators of injury. Nephrol Dial Transplant 15, Suppl 6: 58-60, 2000.
-
(2000)
Nephrol Dial Transplant
, vol.15
, Issue.SUPPL. 6
, pp. 58-60
-
-
Remuzzi, G.1
-
27
-
-
0031042356
-
Understanding the nature of renal disease progression
-
Remuzzi G, Ruggenenti P, Benigni A. Understanding the nature of renal disease progression. Kidney Int 51: 2-15, 1997.
-
(1997)
Kidney Int
, vol.51
, pp. 2-15
-
-
Remuzzi, G.1
Ruggenenti, P.2
Benigni, A.3
-
28
-
-
0014421532
-
Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
-
Risdon RA, Sloper JC, De Wardener HE. Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet 2: 363-366, 1968.
-
(1968)
Lancet
, vol.2
, pp. 363-366
-
-
Risdon, R.A.1
Sloper, J.C.2
De Wardener, H.E.3
-
29
-
-
0035006284
-
Structure and biology of complement protein C3, a connecting link between innate and acquired immunity
-
Sahu A, Lambris JD. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol Rev 180: 35-48, 2001.
-
(2001)
Immunol Rev
, vol.180
, pp. 35-48
-
-
Sahu, A.1
Lambris, J.D.2
-
30
-
-
0030734763
-
Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice
-
Sheerin NS, Springall T, Carroll MC, Hartley B, Sacks SH. Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice. Clin Exp Immunol 110: 403-409, 1997.
-
(1997)
Clin Exp Immunol
, vol.110
, pp. 403-409
-
-
Sheerin, N.S.1
Springall, T.2
Carroll, M.C.3
Hartley, B.4
Sacks, S.H.5
-
31
-
-
0037324549
-
Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo
-
Tang S, Leung JC, Abe K, Chan KW, Chan LY, Chan TM, Lai KN. Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo. J Clin Invest 111: 515-527, 2003.
-
(2003)
J Clin Invest
, vol.111
, pp. 515-527
-
-
Tang, S.1
Leung, J.C.2
Abe, K.3
Chan, K.W.4
Chan, L.Y.5
Chan, T.M.6
Lai, K.N.7
-
32
-
-
33744479974
-
Factor B of the alternative complement pathway regulates development of airway hyper-responsiveness and inflammation
-
Taube C, Thurman JM, Takeda K, Joetham A, Miyahara N, Carroll MC, Dakhama A, Giclas PC, Holers VM, Gelfand EW. Factor B of the alternative complement pathway regulates development of airway hyper-responsiveness and inflammation. Proc Natl Acad Sci USA 103: 8084-8089, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8084-8089
-
-
Taube, C.1
Thurman, J.M.2
Takeda, K.3
Joetham, A.4
Miyahara, N.5
Carroll, M.C.6
Dakhama, A.7
Giclas, P.C.8
Holers, V.M.9
Gelfand, E.W.10
-
33
-
-
31144460785
-
The central role of the alternative complement pathway in human disease
-
Thurman JM, Holers VM. The central role of the alternative complement pathway in human disease. J Immunol 176: 1305-1310, 2006.
-
(2006)
J Immunol
, vol.176
, pp. 1305-1310
-
-
Thurman, J.M.1
Holers, V.M.2
-
34
-
-
5444270100
-
A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice
-
Thurman JM, Kraus DM, Girardi G, Hourcade D, Kang HJ, Royer PA, Mitchell LM, Giclas PC, Salmon J, Gilkeson G, Holers VM. A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice. Mol Immunol 42: 87-97, 2005.
-
(2005)
Mol Immunol
, vol.42
, pp. 87-97
-
-
Thurman, J.M.1
Kraus, D.M.2
Girardi, G.3
Hourcade, D.4
Kang, H.J.5
Royer, P.A.6
Mitchell, L.M.7
Giclas, P.C.8
Salmon, J.9
Gilkeson, G.10
Holers, V.M.11
-
35
-
-
0037310683
-
Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice
-
Thurman JM, Ljubanovic D, Edelstein CL, Gilkeson GS, Holers VM. Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice. J Immunol 170: 1517-1523, 2003.
-
(2003)
J Immunol
, vol.170
, pp. 1517-1523
-
-
Thurman, J.M.1
Ljubanovic, D.2
Edelstein, C.L.3
Gilkeson, G.S.4
Holers, V.M.5
-
36
-
-
32444446595
-
Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/ reperfusion
-
Thurman JM, Ljubanovic D, Royer PA, Kraus DM, Molina H, Barry NP, Proctor G, Levi M, Holers VM. Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/ reperfusion. J Clin Invest 116: 357-368, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 357-368
-
-
Thurman, J.M.1
Ljubanovic, D.2
Royer, P.A.3
Kraus, D.M.4
Molina, H.5
Barry, N.P.6
Proctor, G.7
Levi, M.8
Holers, V.M.9
-
37
-
-
33645453861
-
Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from the induction of apoptosis and renal ischemia/reperfusion injury
-
Thurman JM, Royer PA, Ljubanovic D, Dursun B, Lenderink AM, Edelstein C, Holers VM. Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from the induction of apoptosis and renal ischemia/reperfusion injury. J Am Soc Nephrol 17: 707-715, 2006.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 707-715
-
-
Thurman, J.M.1
Royer, P.A.2
Ljubanovic, D.3
Dursun, B.4
Lenderink, A.M.5
Edelstein, C.6
Holers, V.M.7
-
38
-
-
33748513032
-
Complement activation contributes to both glomerular and tubulointerstitial damage in adriamycin nephropathy in mice
-
Turnberg D, Lewis M, Moss J, Xu Y, Botto M, Cook HT. Complement activation contributes to both glomerular and tubulointerstitial damage in adriamycin nephropathy in mice. J Immunol 177: 4094-4102, 2006.
-
(2006)
J Immunol
, vol.177
, pp. 4094-4102
-
-
Turnberg, D.1
Lewis, M.2
Moss, J.3
Xu, Y.4
Botto, M.5
Cook, H.T.6
-
39
-
-
0035810399
-
Complement. First of two parts
-
Walport MJ. Complement. First of two parts. N Engl J Med 344: 1058-1066, 2001.
-
(2001)
N Engl J Med
, vol.344
, pp. 1058-1066
-
-
Walport, M.J.1
-
40
-
-
0033802098
-
Progressive adriamycin nephropathy in mice: Sequence of histologic and immunohistochemical events
-
Wang Y, Wang YP, Tay YC, Harris DC. Progressive adriamycin nephropathy in mice: sequence of histologic and immunohistochemical events. Kidney Int 58: 1797-1804, 2000.
-
(2000)
Kidney Int
, vol.58
, pp. 1797-1804
-
-
Wang, Y.1
Wang, Y.P.2
Tay, Y.C.3
Harris, D.C.4
-
41
-
-
0034650431
-
Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B
-
Watanabe H, Garnier G, Circolo A, Wetsel RA, Ruiz P, Holers VM, Boackle SA, Colten HR, Gilkeson GS. Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B. J Immunol 164: 786-794, 2000.
-
(2000)
J Immunol
, vol.164
, pp. 786-794
-
-
Watanabe, H.1
Garnier, G.2
Circolo, A.3
Wetsel, R.A.4
Ruiz, P.5
Holers, V.M.6
Boackle, S.A.7
Colten, H.R.8
Gilkeson, G.S.9
|