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Volumn 90, Issue 1, 2016, Pages 109-122

Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury

Author keywords

complement; glomerulonephritis; inflammation

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; COMPLEMENT FACTOR H; PROTEIN CRRY; REGULATOR PROTEIN; UNCLASSIFIED DRUG; COMPLEMENT RECEPTOR; CRRY PROTEIN, MOUSE;

EID: 84988443352     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2016.02.036     Document Type: Article
Times cited : (17)

References (54)
  • 1
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • 1 Ricklin, D., Hajishengallis, G., Yang, K., Lambris, J.D., Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11 (2010), 785–797.
    • (2010) Nat Immunol , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 2
    • 70349437186 scopus 로고    scopus 로고
    • Complement regulators and inhibitory proteins
    • 2 Zipfel, P.F., Skerka, C., Complement regulators and inhibitory proteins. Nat Rev Immunol 9 (2009), 729–740.
    • (2009) Nat Rev Immunol , vol.9 , pp. 729-740
    • Zipfel, P.F.1    Skerka, C.2
  • 3
    • 36849084660 scopus 로고    scopus 로고
    • Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H
    • 3 de Cordoba, S.R., de Jorge, E.G., Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H. Clin Exp Immunol 151 (2008), 1–13.
    • (2008) Clin Exp Immunol , vol.151 , pp. 1-13
    • de Cordoba, S.R.1    de Jorge, E.G.2
  • 4
    • 84888641200 scopus 로고    scopus 로고
    • C3 glomerulopathy: consensus report
    • 4 Pickering, M.C., D'Agati, V.D., Nester, C.M., et al. C3 glomerulopathy: consensus report. Kidney Int 84 (2013), 1079–1089.
    • (2013) Kidney Int , vol.84 , pp. 1079-1089
    • Pickering, M.C.1    D'Agati, V.D.2    Nester, C.M.3
  • 5
    • 34147180032 scopus 로고    scopus 로고
    • Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome
    • 5 Servais, A., Fremeaux-Bacchi, V., Lequintrec, M., et al. Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome. J Med Genet 44 (2007), 193–199.
    • (2007) J Med Genet , vol.44 , pp. 193-199
    • Servais, A.1    Fremeaux-Bacchi, V.2    Lequintrec, M.3
  • 6
    • 84864554927 scopus 로고    scopus 로고
    • Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
    • 6 Servais, A., Noel, L.H., Roumenina, L.T., et al. Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies. Kidney Int 82 (2012), 454–464.
    • (2012) Kidney Int , vol.82 , pp. 454-464
    • Servais, A.1    Noel, L.H.2    Roumenina, L.T.3
  • 7
    • 77957827919 scopus 로고    scopus 로고
    • Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation
    • 7 Martinez-Barricarte, R., Heurich, M., Valdes-Canedo, F., et al. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. J Clin Invest 120 (2010), 3702–3712.
    • (2010) J Clin Invest , vol.120 , pp. 3702-3712
    • Martinez-Barricarte, R.1    Heurich, M.2    Valdes-Canedo, F.3
  • 8
    • 84878548121 scopus 로고    scopus 로고
    • C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation
    • 8 Tortajada, A., Yebenes, H., Abarrategui-Garrido, C., et al. C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation. J Clin Invest 123 (2013), 2434–2446.
    • (2013) J Clin Invest , vol.123 , pp. 2434-2446
    • Tortajada, A.1    Yebenes, H.2    Abarrategui-Garrido, C.3
  • 9
    • 84892930196 scopus 로고    scopus 로고
    • Complement factor H-related hybrid protein deregulates complement in dense deposit disease
    • 9 Chen, Q., Wiesener, M., Eberhardt, H.U., et al. Complement factor H-related hybrid protein deregulates complement in dense deposit disease. J Clin Invest 124 (2014), 145–155.
    • (2014) J Clin Invest , vol.124 , pp. 145-155
    • Chen, Q.1    Wiesener, M.2    Eberhardt, H.U.3
  • 10
    • 84863115476 scopus 로고    scopus 로고
    • Causes of alternative pathway dysregulation in dense deposit disease
    • 10 Zhang, Y., Meyer, N.C., Wang, K., et al. Causes of alternative pathway dysregulation in dense deposit disease. Clin J Am Soc Nephrol 7 (2012), 265–274.
    • (2012) Clin J Am Soc Nephrol , vol.7 , pp. 265-274
    • Zhang, Y.1    Meyer, N.C.2    Wang, K.3
  • 11
    • 1542318912 scopus 로고    scopus 로고
    • Heterozygous and homozygous factor H deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases
    • 11 Dragon-Durey, M.A., Fremeaux-Bacchi, V., Loirat, C., et al. Heterozygous and homozygous factor H deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases. J Am Soc Nephrol 15 (2004), 787–795.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 787-795
    • Dragon-Durey, M.A.1    Fremeaux-Bacchi, V.2    Loirat, C.3
  • 12
    • 67349180237 scopus 로고    scopus 로고
    • C3 deposition glomerulopathy due to a functional factor H defect
    • 12 Habbig, S., Mihatsch, M.J., Heinen, S., et al. C3 deposition glomerulopathy due to a functional factor H defect. Kidney Int 75 (2009), 1230–1234.
    • (2009) Kidney Int , vol.75 , pp. 1230-1234
    • Habbig, S.1    Mihatsch, M.J.2    Heinen, S.3
  • 13
    • 0036699540 scopus 로고    scopus 로고
    • Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
    • 13 Pickering, M.C., Cook, H.T., Warren, J., et al. Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat Genet 31 (2002), 424–428.
    • (2002) Nat Genet , vol.31 , pp. 424-428
    • Pickering, M.C.1    Cook, H.T.2    Warren, J.3
  • 14
    • 84937974621 scopus 로고    scopus 로고
    • Glomerular diseases dependent on complement activation, including atypical hemolytic uremic syndrome, membranoproliferative glomerulonephritis, and C3 glomerulopathy: core curriculum 2015
    • 14 Noris, M., Remuzzi, G., Glomerular diseases dependent on complement activation, including atypical hemolytic uremic syndrome, membranoproliferative glomerulonephritis, and C3 glomerulopathy: core curriculum 2015. Am J Kidney Dis 66 (2015), 359–375.
    • (2015) Am J Kidney Dis , vol.66 , pp. 359-375
    • Noris, M.1    Remuzzi, G.2
  • 15
    • 32444446595 scopus 로고    scopus 로고
    • Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion
    • 15 Thurman, J.M., Ljubanovic, D., Royer, P.A., et al. Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion. J Clin Invest 116 (2006), 357–368.
    • (2006) J Clin Invest , vol.116 , pp. 357-368
    • Thurman, J.M.1    Ljubanovic, D.2    Royer, P.A.3
  • 16
    • 78049388842 scopus 로고    scopus 로고
    • The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells
    • 16 Renner, B., Coleman, K., Goldberg, R., et al. The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells. J Immunol 185 (2010), 3086–3094.
    • (2010) J Immunol , vol.185 , pp. 3086-3094
    • Renner, B.1    Coleman, K.2    Goldberg, R.3
  • 17
    • 33947256458 scopus 로고    scopus 로고
    • Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure
    • 17 Bao, L., Wang, Y., Chang, A., et al. Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure. J Am Soc Nephrol 18 (2007), 811–822.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 811-822
    • Bao, L.1    Wang, Y.2    Chang, A.3
  • 18
    • 84926147452 scopus 로고    scopus 로고
    • Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury
    • 18 Miao, J., Lesher, A.M., Miwa, T., et al. Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury. Kidney Int 86 (2014), 726–737.
    • (2014) Kidney Int , vol.86 , pp. 726-737
    • Miao, J.1    Lesher, A.M.2    Miwa, T.3
  • 19
    • 0028239796 scopus 로고
    • Localization of the complement regulatory proteins in the normal human kidney
    • 19 Ichida, S., Yuzawa, Y., Okada, H., et al. Localization of the complement regulatory proteins in the normal human kidney. Kidney Int 46 (1994), 89–96.
    • (1994) Kidney Int , vol.46 , pp. 89-96
    • Ichida, S.1    Yuzawa, Y.2    Okada, H.3
  • 20
    • 0034695647 scopus 로고    scopus 로고
    • A critical role for murine complement regulator Crry in fetomaternal tolerance
    • 20 Xu, C., Mao, D., Holers, V.M., et al. A critical role for murine complement regulator Crry in fetomaternal tolerance. Science 287 (2000), 498–501.
    • (2000) Science , vol.287 , pp. 498-501
    • Xu, C.1    Mao, D.2    Holers, V.M.3
  • 21
    • 0035810399 scopus 로고    scopus 로고
    • Complement: first of two parts
    • 21 Walport, M.J., Complement: first of two parts. N Engl J Med 344 (2001), 1058–1066.
    • (2001) N Engl J Med , vol.344 , pp. 1058-1066
    • Walport, M.J.1
  • 22
    • 77954761090 scopus 로고    scopus 로고
    • Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice
    • 22 Fakhouri, F., de Jorge, E.G., Brune, F., et al. Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice. Kidney Int 78 (2010), 279–286.
    • (2010) Kidney Int , vol.78 , pp. 279-286
    • Fakhouri, F.1    de Jorge, E.G.2    Brune, F.3
  • 23
    • 84877145565 scopus 로고    scopus 로고
    • Detection of complement activation using monoclonal antibodies against C3d
    • 23 Thurman, J.M., Kulik, L., Orth, H., et al. Detection of complement activation using monoclonal antibodies against C3d. J Clin Invest 123 (2013), 2218–2230.
    • (2013) J Clin Invest , vol.123 , pp. 2218-2230
    • Thurman, J.M.1    Kulik, L.2    Orth, H.3
  • 24
    • 0036865356 scopus 로고    scopus 로고
    • Structure and function of complement C5 convertase enzymes
    • 24 Pangburn, M.K., Rawal, N., Structure and function of complement C5 convertase enzymes. Biochem Soc Trans 30 (2002), 1006–1010.
    • (2002) Biochem Soc Trans , vol.30 , pp. 1006-1010
    • Pangburn, M.K.1    Rawal, N.2
  • 25
    • 65549156675 scopus 로고    scopus 로고
    • Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase
    • 25 Paixao-Cavalcante, D., Hanson, S., Botto, M., et al. Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase. Mol Immunol 46 (2009), 1942–1950.
    • (2009) Mol Immunol , vol.46 , pp. 1942-1950
    • Paixao-Cavalcante, D.1    Hanson, S.2    Botto, M.3
  • 26
    • 0037310683 scopus 로고    scopus 로고
    • Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice
    • 26 Thurman, J.M., Ljubanovic, D., Edelstein, C.L., et al. Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice. J Immunol 170 (2003), 1517–1523.
    • (2003) J Immunol , vol.170 , pp. 1517-1523
    • Thurman, J.M.1    Ljubanovic, D.2    Edelstein, C.L.3
  • 27
    • 53149126901 scopus 로고    scopus 로고
    • Membrane protein Crry maintains homeostasis of the complement system
    • 27 Wu, X., Spitzer, D., Mao, D., et al. Membrane protein Crry maintains homeostasis of the complement system. J Immunol 181 (2008), 2732–2740.
    • (2008) J Immunol , vol.181 , pp. 2732-2740
    • Wu, X.1    Spitzer, D.2    Mao, D.3
  • 28
    • 84863511490 scopus 로고    scopus 로고
    • A hybrid CFHR3-1 gene causes familial C3 glomerulopathy
    • 28 Malik, T.H., Lavin, P.J., Goicoechea de Jorge, E., et al. A hybrid CFHR3-1 gene causes familial C3 glomerulopathy. J Am Soc Nephrol 23 (2012), 1155–1160.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1155-1160
    • Malik, T.H.1    Lavin, P.J.2    Goicoechea de Jorge, E.3
  • 29
    • 77956394517 scopus 로고    scopus 로고
    • Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis
    • 29 Gale, D.P., de Jorge, E.G., Cook, H.T., et al. Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis. Lancet 376 (2010), 794–801.
    • (2010) Lancet , vol.376 , pp. 794-801
    • Gale, D.P.1    de Jorge, E.G.2    Cook, H.T.3
  • 30
    • 77950628002 scopus 로고    scopus 로고
    • Anti-factor B autoantibody in dense deposit disease
    • 30 Strobel, S., Zimmering, M., Papp, K., et al. Anti-factor B autoantibody in dense deposit disease. Mol Immunol 47 (2010), 1476–1483.
    • (2010) Mol Immunol , vol.47 , pp. 1476-1483
    • Strobel, S.1    Zimmering, M.2    Papp, K.3
  • 31
    • 79958192481 scopus 로고    scopus 로고
    • Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees
    • 31 Athanasiou, Y., Voskarides, K., Gale, D.P., et al. Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees. Clin J Am Soc Nephrol 6 (2011), 1436–1446.
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 1436-1446
    • Athanasiou, Y.1    Voskarides, K.2    Gale, D.P.3
  • 32
    • 84897954452 scopus 로고    scopus 로고
    • A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry
    • 32 Medjeral-Thomas, N., Malik, T.H., Patel, M.P., et al. A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry. Kidney Int 85 (2014), 933–937.
    • (2014) Kidney Int , vol.85 , pp. 933-937
    • Medjeral-Thomas, N.1    Malik, T.H.2    Patel, M.P.3
  • 33
    • 33645453861 scopus 로고    scopus 로고
    • Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury
    • 33 Thurman, J.M., Royer, P.A., Ljubanovic, D., et al. Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury. J Am Soc Nephrol 17 (2006), 707–715.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 707-715
    • Thurman, J.M.1    Royer, P.A.2    Ljubanovic, D.3
  • 34
    • 70350279315 scopus 로고    scopus 로고
    • Atypical hemolytic-uremic syndrome
    • 34 Noris, M., Remuzzi, G., Atypical hemolytic-uremic syndrome. N Engl J Med 361 (2009), 1676–1687.
    • (2009) N Engl J Med , vol.361 , pp. 1676-1687
    • Noris, M.1    Remuzzi, G.2
  • 35
    • 34548381835 scopus 로고    scopus 로고
    • The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy
    • 35 Lenderink, A.M., Liegel, K., Ljubanovic, D., et al. The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy. Am J Physiol Renal Physiol 293 (2007), F555–F564.
    • (2007) Am J Physiol Renal Physiol , vol.293 , pp. F555-F564
    • Lenderink, A.M.1    Liegel, K.2    Ljubanovic, D.3
  • 36
    • 0034650431 scopus 로고    scopus 로고
    • Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B
    • 36 Watanabe, H., Garnier, G., Circolo, A., et al. Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B. J Immunol 164 (2000), 786–794.
    • (2000) J Immunol , vol.164 , pp. 786-794
    • Watanabe, H.1    Garnier, G.2    Circolo, A.3
  • 37
    • 33847052568 scopus 로고    scopus 로고
    • Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies
    • 37 Xiao, H., Schreiber, A., Heeringa, P., et al. Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies. Am J Pathol 170 (2007), 52–64.
    • (2007) Am J Pathol , vol.170 , pp. 52-64
    • Xiao, H.1    Schreiber, A.2    Heeringa, P.3
  • 38
    • 34249112293 scopus 로고    scopus 로고
    • Dense deposit disease is not a membranoproliferative glomerulonephritis
    • 38 Walker, P.D., Ferrario, F., Joh, K., Bonsib, S.M., Dense deposit disease is not a membranoproliferative glomerulonephritis. Mod Pathol 20 (2007), 605–616.
    • (2007) Mod Pathol , vol.20 , pp. 605-616
    • Walker, P.D.1    Ferrario, F.2    Joh, K.3    Bonsib, S.M.4
  • 39
  • 40
    • 0347480217 scopus 로고    scopus 로고
    • Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway
    • 40 Mao, D., Wu, X., Deppong, C., et al. Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway. Immunity 19 (2003), 813–822.
    • (2003) Immunity , vol.19 , pp. 813-822
    • Mao, D.1    Wu, X.2    Deppong, C.3
  • 41
    • 59249091655 scopus 로고    scopus 로고
    • Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury
    • 41 Ruseva, M.M., Hughes, T.R., Donev, R.M., et al. Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. Mol Immunol 46 (2009), 803–811.
    • (2009) Mol Immunol , vol.46 , pp. 803-811
    • Ruseva, M.M.1    Hughes, T.R.2    Donev, R.M.3
  • 42
    • 38849102544 scopus 로고    scopus 로고
    • Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice
    • 42 Rose, K.L., Paixao-Cavalcante, D., Fish, J., et al. Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest 118 (2008), 608–618.
    • (2008) J Clin Invest , vol.118 , pp. 608-618
    • Rose, K.L.1    Paixao-Cavalcante, D.2    Fish, J.3
  • 43
    • 84951570509 scopus 로고    scopus 로고
    • An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy
    • 43 Nichols, E.M., Barbour, T.D., Pappworth, I.Y., et al. An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy. Kidney Int 88 (2015), 1314–1322.
    • (2015) Kidney Int , vol.88 , pp. 1314-1322
    • Nichols, E.M.1    Barbour, T.D.2    Pappworth, I.Y.3
  • 44
    • 84970928343 scopus 로고    scopus 로고
    • Efficacy of targeted complement inhibition in experimental C3 glomerulopathy
    • 44 Ruseva, M.M., Peng, T., Lasaro, M.A., et al. Efficacy of targeted complement inhibition in experimental C3 glomerulopathy. J Am Soc Nephrol 27 (2016), 405–416.
    • (2016) J Am Soc Nephrol , vol.27 , pp. 405-416
    • Ruseva, M.M.1    Peng, T.2    Lasaro, M.A.3
  • 45
    • 35948959015 scopus 로고    scopus 로고
    • Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria
    • 45 Rother, R.P., Rollins, S.A., Mojcik, C.F., et al. Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria. Nat Biotechnol 25 (2007), 1256–1264.
    • (2007) Nat Biotechnol , vol.25 , pp. 1256-1264
    • Rother, R.P.1    Rollins, S.A.2    Mojcik, C.F.3
  • 46
    • 29144459115 scopus 로고    scopus 로고
    • Selective and efficient inhibition of the alternative pathway of complement by a mAb that recognizes C3b/iC3b
    • 46 DiLillo, D.J., Pawluczkowycz, A.W., Peng, W., et al. Selective and efficient inhibition of the alternative pathway of complement by a mAb that recognizes C3b/iC3b. Mol Immunol 43 (2006), 1010–1019.
    • (2006) Mol Immunol , vol.43 , pp. 1010-1019
    • DiLillo, D.J.1    Pawluczkowycz, A.W.2    Peng, W.3
  • 47
    • 79960446438 scopus 로고    scopus 로고
    • Complement factor I in health and disease
    • 47 Nilsson, S.C., Sim, R.B., Lea, S.M., et al. Complement factor I in health and disease. Mol Immunol 48 (2011), 1611–1620.
    • (2011) Mol Immunol , vol.48 , pp. 1611-1620
    • Nilsson, S.C.1    Sim, R.B.2    Lea, S.M.3
  • 48
    • 84861566815 scopus 로고    scopus 로고
    • Plasminogen is a complement inhibitor
    • 48 Barthel, D., Schindler, S., Zipfel, P.F., Plasminogen is a complement inhibitor. J Biol Chem 287 (2012), 18831–18842.
    • (2012) J Biol Chem , vol.287 , pp. 18831-18842
    • Barthel, D.1    Schindler, S.2    Zipfel, P.F.3
  • 49
    • 33947602404 scopus 로고    scopus 로고
    • Complement and coagulation: strangers or partners in crime?
    • 49 Markiewski, M.M., Nilsson, B., Ekdahl, K.N., et al. Complement and coagulation: strangers or partners in crime?. Trends Immunol 28 (2007), 184–192.
    • (2007) Trends Immunol , vol.28 , pp. 184-192
    • Markiewski, M.M.1    Nilsson, B.2    Ekdahl, K.N.3
  • 50
    • 0023357139 scopus 로고
    • Generation of a monoclonal antibody to mouse C5 application in an ELISA assay for detection of anti-C5 antibodies
    • 50 Frei, Y., Lambris, J.D., Stockinger, B., Generation of a monoclonal antibody to mouse C5 application in an ELISA assay for detection of anti-C5 antibodies. Mol Cell Probes 1 (1987), 141–149.
    • (1987) Mol Cell Probes , vol.1 , pp. 141-149
    • Frei, Y.1    Lambris, J.D.2    Stockinger, B.3
  • 51
    • 72049127823 scopus 로고    scopus 로고
    • Th1 and Th17 cells induce proliferative glomerulonephritis
    • 51 Summers, S.A., Steinmetz, O.M., Li, M., et al. Th1 and Th17 cells induce proliferative glomerulonephritis. J Am Soc Nephrol 20 (2009), 2518–2524.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2518-2524
    • Summers, S.A.1    Steinmetz, O.M.2    Li, M.3
  • 52
    • 5444270100 scopus 로고    scopus 로고
    • A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice
    • 52 Thurman, J.M., Kraus, D.M., Girardi, G., et al. A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice. Mol Immunol 42 (2005), 87–97.
    • (2005) Mol Immunol , vol.42 , pp. 87-97
    • Thurman, J.M.1    Kraus, D.M.2    Girardi, G.3
  • 53
    • 80055093313 scopus 로고    scopus 로고
    • Sudan black B reduces autofluorescence in murine renal tissue
    • 53 Sun, Y., Yu, H., Zheng, D., et al. Sudan black B reduces autofluorescence in murine renal tissue. Arch Pathol Lab Med 135 (2011), 1335–1342.
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 1335-1342
    • Sun, Y.1    Yu, H.2    Zheng, D.3
  • 54
    • 84940787811 scopus 로고    scopus 로고
    • IgM exacerbates glomerular disease progression in complement-induced glomerulopathy
    • 54 Panzer, S.E., Laskowski, J., Renner, B., et al. IgM exacerbates glomerular disease progression in complement-induced glomerulopathy. Kidney Int 88 (2015), 528–537.
    • (2015) Kidney Int , vol.88 , pp. 528-537
    • Panzer, S.E.1    Laskowski, J.2    Renner, B.3


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