Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches

Blood

Volumn 128, Issue 25, 2016, Pages 2949-2959

  Antonelli, Antonella ^a   Noort, Willy A ^b   Jaques, Jenny ^a   De Boer, Bauke ^a   De Jong Korlaar, Regina ^b   Brouwers Vos, Annet Z ^a   Lubbers Aalders, Linda ^b   Van Velzen, Jeroen F ^c   Bloem, Andries C ^c   Yuan, Huipin ^d   De Bruijn, Joost D ^e   Ossenkoppele, Gert J ^b   Martens, Anton C M ^b   Vellenga, Edo ^a   Groen, Richard W J ^b   Schuringa, Jan Jacob ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d XPand Biotechnology BV   (Netherlands)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTOME;

ACUTE MYELOID LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; CONTROLLED STUDY; EXOME; GENE EXPRESSION PROFILING; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; LEUKEMIA CELL; MESENCHYMAL STROMA CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STEM CELL SELF-RENEWAL; TRANSPLANTATION; XENOGRAFT; ANIMAL; CELL CLONE; CELL SELF-RENEWAL; CELL SEPARATION; CHEMISTRY; CYTOLOGY; DRUG SCREENING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIETIC STEM CELL; PATHOLOGY; STEM CELL NICHE; STROMA CELL; TISSUE SCAFFOLD;

ANIMALS; BONE MARROW; CELL SELF RENEWAL; CELL SEPARATION; CLONE CELLS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MESENCHYMAL STROMAL CELLS; MICE; PHENOTYPE; STEM CELL NICHE; STROMAL CELLS; TISSUE SCAFFOLDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85013209741     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-05-719021     Document Type: Article

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