Therapy of HIV Infection: Current Approaches and Prospects

Acta Naturae

Volumn 8, Issue 4, 2016, Pages 23-32

  Prokofjeva, M M ^a   Kochetkov, S N ^a   Prassolov, V S ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Antiviral therapy; Genome editing; HAART highly active antiretroviral therapy; HIV human immunodeficiency virus; HIV 1; LTR long terminal repeat; NNRTI non nucleoside reverse transcriptase inhibitor; NRTI nucleoside reverse transcriptase inhibitor; RT reverse transcriptase; Viral life cycle inhibitors

Indexed keywords

EID: 85013141276     PISSN: 20758251     EISSN: None     Source Type: Journal    
DOI: 10.32607/20758251-2016-8-4-23-32     Document Type: Article

References (72)

1. De Clercq E.//Rev. Med. Virol. 2009. V. 19. P. 287-299.
2. Roberts J.D., Bebenek K., Kunkel T.A.//Science. 1988. V. 242. No. 4882. P. 1171-1173.
3. Clapham P.R., McKnight A.//Br. Med. Bull. 2001. V. 58. P. 43-59.
4. Benkirane M., Jin D.Y., Chun R.F., Koup R.A., Jeang K.T.//J. Biol. Chem. 1997. V. 272. P. 30603-30606.
5. Wilkinson D.A., Operskalski E.A., Busch M.P., Mosley J.W., Koup R.A.//J. Infect. Dis. 1998. V. 178. P. 1163-1166.
6. Depienne C., Mousnier A., Leh H., Le Rouzic E., Dormont D., Benichou S., Dargemont C.//J. Biol. Chem. 2001. V. 276. P. 18102-18107.
7. Ganser-Pornillos B.K., Yeager M., Sundquist W.//Curr. Opin. Struct. Biol. 2008. V. 18. P. 203-217.
8. Cihlar T., Ray A.S.//Antiviral Res. 2010. V. 85. P. 39-58.
9. Lavie A., Schlichting I., Vetter I.R., Konrad M., Reinstein J., Goody R.S.//Nat. Med. 1997. V. 3. P. 922-924.
10. Lavie A., Vetter I.R., Konrad M., Goody R.S., Reinstein J., Schlichting I.//Nat. Struct. Biol. 1997. V. 4. P. 601-604.
11. Schneider B., Xu Y. W., Sellam O., Sarfati R., Janin J., Veron M., Deville-Bonne D.//J. Biol. Chem. 1998. V. 273. No. 19. P. 11491-11497.
12. Nakashima H., Matsui T., Harada S., Kobayashi N., Matsuda A., Ueda T., Yamamoto N.//Antimicrob. Agents Chemother. 1986. V. 30. No. 6. P. 933-937.
13. Doong S.L., Tsai C.H., Schinazi R.F., Liotta D.C., Cheng Y.C.//Proc. Natl. Acad. Sci. USA. 1991. V. 88. No. 19. P. 8495-8499.
14. Furman P.A., Davis M., Liotta D.C., Paff M., Frick L.W., Nelson D.J., Dornsife R.E., Wurster J.A., Wilson L.J., Fyfe J.A., et al.//Antimicrob. Agents Chemother. 1992. V. 36. No. 12. P. 2686-2692.
15. Hoong L.K., Strange L.E., Liotta D.C., Koszalka G.W., Burns C.L., Schinazi R.F.//J. Org. Chem. 1992. V. 57. P. 5563-5565.
16. Schinazi R.F., McMillan A., Cannon D., Mathis R., Lloyd R.M., Peck A., Sommadossi J.P., St Clair M., Wilson J., Furman P.A., et al.//Antimicrob. Agents Chemother. 1992. V. 36. No. 11. P. 2423-2431.
17. Schinazi R.F., Boudinot F.D., Ibrahim S.S., Manning C., McClure H.M., Liotta D.C.//Antimicrob. Agents Chemother. 1992. V. 36. P. 2432-2438.
18. Hooker D.J., Tachedjian G., Solomon A.E., Gurusinghe A.D., Land S., Birch C., Anderson J.L., Roy B.M., Arnold E., Deacon N.J.//J. Virol. 1996. V. 70. No. 11. P. 8010-8018.
19. Cruchaga C., Anso E., Rouzaut A., Martínez-Irujo J.J.//J. Biol. Chem. 2006. V. 281. No. 38. P. 27744-27752.
20. Coffin J.M.//Science. 1995. V. 267. No. 5197. P. 483-489.
21. Larder B.A., Darby G., Richman D.D.//Science. 1989. V. 243. No. 4899. P. 1731-1734.
22. Goldschmidt V., Marquet R.//Int. J. Biochem. Cell. Biol. 2004. V. 36. No. 9. P. 1687-1705.
23. Deval J., Courcambeck J., Selmi B., Boretto J., Canard B.//Curr. Drug Metab. 2004. V. 5. No. 4. P. 305-316.
24. Naeger L.K., Margot N.A., Miller M.D.//Antimicrob. Agents Chemother. 2002. V. 46. No. 7. P. 2179-2184.
25. de Béthune M.//Antiviral Res. 2010. V. 85. P. 75-90.
26. Grob P.M., Wu J.C., Cohen K.A., Ingraham R.H., Shih C.K., Hargrave K.D., McTague T.L., Merluzzi V.J.//AIDS Res. Hum. Retroviruses. 1992. V. 8. No. 2. P. 145-152.
27. De Clercq E.//Chem. Biodivers. 2004. V. 1. No. 1. P. 44-64.
28. Debyser Z., Pauwels R., Andries K., Desmyter J., Kukla M., Janssen P.A., De Clercq E.//Proc. Natl. Acad. Sci. USA. 1991. V. 88. No. 4. P. 1451-1455.
29. Althaus I.W., Chou J.J., Gonzales A.J., Deibel M.R., Chou K.C., Kezdy F.J., Romero D.L., Palmer J.R., Thomas R.C., Aristoff P.A., et al.//Biochemistry. 1993. V. 32. No. 26. P. 6548-6554.
30. Ren J., Milton J., Weaver K.L., Short S.A., Stuart D.I., Stammers D.K.//Structure. 2000. V. 8. No. 10. P. 1089-1094.
31. Fletcher R.S., Syed K., Mithani S., Dmitrienko G.I., Parniak M.A.//Biochemistry. 1995. V. 34. No. 13. P. 4346-4353.
32. Rittinger K., Divita G., Goody R.S.//Proc. Natl. Acad. Sci. USA. 1995. V. 92. No. 17. P. 8046-8049.
33. Zhou Z., Madrid M., Evanseck J.D., Madura J.D.//J. Am. Chem. Soc. 2005. V. 127. No. 49. P. 17253-17260.
34. Hang J.Q., Li Y., Yang Y., Cammack N., Mirzadegan T., Klumpp K.//Biochem. Biophys. Res. Commun. 2007. V. 352. No. 2. P. 341-350.
35. Janssen P.A.J., Lewi P.J., Arnold E., Daeyaert F., de Jonge M., Heeres J., Koymans L., Vinkers M., Guillemont J., Pasquier E., et al.//J. Med. Chem. 2005. V. 48. No. 6. P. 1901-1909.
36. Madruga J.V., Cahn P., Grinsztejn B., Haubrich R., Lalezari J., Mills A., Pialoux G., Wilkin T., Peeters M., Vingerhoets J., et al.//Lancet. 2007. V. 370. No. 9581. P. 29-38.
37. Lazzarin A., Campbell T., Clotet B., Johnson M., Katlama C., Moll A., Towner W., Trottier B., Peeters M., Vingerhoets J., et al.//Lancet. 2007. V. 370. No. 9581. P. 39-48.
38. Pauwels R.//Antiviral Res. 2006. V. 71. No. 2-3. P. 77-89.
39. Roberts N.A., Martin J.A., Kinchington D., Broadhurst A.V., Craig J.C., Duncan I.B., Galpin S.A., Handa B.K., Kay J., Kröhn A., et al.//Science. 1990. V. 248. No. 4953. P. 358-361.
40. Clavel F., Hance A.J.//N. Engl. J. Med. 2004. V. 350. No. 10. P. 1023-1035.
41. Wensing A.M.J., van Maarseveen N.M., Nijhuis M.//Antiviral Res. 2010. V. 85. P. 59-74.
42. Hazuda D.J., Felock P., Witmer M., Wolfe A., Stillmock K., Grobler J.A., Espeseth A., Gabryelski L., Schleif W., Blau C., et al.//Science. 2000. V. 287. No. 5453. P. 646-650.
43. Grinsztejn B., Nguyen B.Y., Katlama C., Gatell J.M., Lazzarin A., Vittecoq D., Gonzalez C.J., Chen J., Harvey C.M., Isaacs R.D., et al.//Lancet. 2007. V. 369. No. 9569. P. 1261-1269.
44. Steigbigel R.T., Cooper D.A., Kumar P.N., Eron J.E., Schechter M., Markowitz M., Loutfy M.R., Lennox J.L., Gatell J.M., Rockstroh J.K., et al.//N. Engl. J. Med. 2008. V. 359. No. 4. P. 339-354.
45. Cooper D.A., Steigbigel R.T., Gatell J.M., Rockstroh J.K., Katlama C., Yeni P., Lazzarin A., Clotet B., Kumar P.N., Eron J.E., et al.//N. Engl. J. Med. 2008. V. 359. No. 4. P. 355-365.
46. Matthews T., Salgo M., Greenberg M., Chung J., DeMasi R., Bolognesi D.//Nat. Rev. Drug Discov. 2004. V. 3. No. 3. P. 215-225.
47. Wild C., Greenwell T., Matthews T.//AIDS Res. Hum. Retroviruses. 1993. V. 9. No. 11. P. 1051-1053.
48. Perros M.//Adv. Antiviral Drug Design. 2007. V. 5. P. 185-212.
49. Baba M., Snoeck R., Pauwels R., De Clercq E.//Antimicrob. Agents Chemother. 1988. V. 32. No. 11. P. 1742-1745.
50. Prokofjeva M.M., Imbs T.I., Shevchenko N.M., Spirin P.V., Horn S., Fehse B., Zvyagintseva T.N., Prassolov V.S.//Marine Drugs. 2013. V. 11. No. 8. P. 3000-3014.
51. Siliciano J.D., Kajdas J., Finzi D., Quinn T.C., Chadwick K., Margolick J.B., Kovacs C., Gange S.J., Siliciano R.F.//Nat. Med. 2003. V. 9. P. 727-728.
52. Adams M., Sharmeen L., Kimpton J., Romeo J.M., Garcia J.V., Peterlin B.M., Groudine M., Emerman M.//Proc. Natl. Acad. Sci. USA. 1994. V. 91. No. 9. P. 3862-3866.
53. Chun T.W., Stuyver L., Mizell S.B., Ehler L.A., Mican J.A., Baseler M., Lloyd A.L., Nowak M.A., Fauci A.S.//Proc. Natl. Acad. Sci. USA. 1997. V. 94. No. 24. P. 13193-13197.
54. Autran B., Carcelain G., Combadiere B., Debre P.//Science. 2004. V. 305. No. 5681. P. 205-208.
55. Carcelain G., Autran B.//Immunol Rev. 2013. V. 254. No. 1. P. 355-371.
56. Shingai M., Donau O.K., Plishka R.J., Buckler-White A., Mascola J.R., Nabel G.J., Nason M.C., Montefiori D., Moldt B., Poignard P., et al.//J. Exp. Med. 2014. V. 211. No. 10. P. 2061-2074.
57. Caskey M., Klein F., Lorenzi J.C., Seaman M.S., West A.P. Jr., Buckley N., Kremer G., Nogueira L., Braunschweig M., Scheid J.F., et al.//Nature. 2015. V. 522. No. 7557. P. 487-491.
58. Hutter G., Nowak D., Mossner M., Ganepola S., Mussig A., Allers K., Schneider T., Hofmann J., Kücherer C., Blau O., et al.//N. Engl. J. Med. 2009. V. 360. No. 7. P. 692-698.
59. Archin N.M., Liberty A.L., Kashuba A.D., Choudhary S.K., Kuruc J.D., Crooks A.M., Parker D.C., Anderson E.M., Kearney M.F., Strain M.C., et al.//Nature. 2012. V. 487. P. 482-485.
60. Rasmussen T.A., Tolstrup M., Brinkmann C.R., Olesen R., Erikstrup C., Solomon A., Winckelmann A., Palmer S., Dinarello C., Buzon M., et al.//Lancet HIV. 2014. V. 1. No. 1. P. e13-21.
61. Søgaard O.S., Graversen M.E., Leth S., Olesen R., Brinkmann C.R., Nissen S.K., Kjaer A.S., Schleimann M.H., Denton P.W., Hey-Cunningham W.J., et al.//PLoS Pathog. 2015. V. 11. No. 9. P. e1005142.
62. Shan L., Deng K., Shroff N.S., Durand C.M., Rabi S.A., Yang H.C., Zhang H., Margolick J.B., Blankson J.N., Siliciano R.F.//Immunity. 2012. V. 36. No. 3. P. 491-501.
63. Jones L.E., Perelson A.S.//J. Acquir. Immune Defic. Syndr. 2007. V. 45. No. 5. P. 483-493.
64. Sklar P.A., Ward D.J., Baker R.K., Wood K.C., Gafoor Z., Alzola C.F., Moorman A.C., Holmberg S.D.//AIDS. 2002. V. 16. No. 15. P. 2035-2041.
65. Cecchetti V., Parolin C., Moro S., Pecere T., Filipponi E., Calistri A., Tabarrini O., Gatto B., Palumbo M., Fravolini A., et al.//J. Med. Chem. 2000. V. 43. No. 20. P. 3799-3802.
66. Parolin C., Gatto B., Del Vecchio C., Pecere T., Tramontano E., Cecchetti V., Fravolini A., Masiero S., Palumbo M., Palu G.//Antimicrob. Agents Chemother. 2003. V. 47. No. 3. P. 889-896.
67. Tabarrini O., Stevens M., Cecchetti V., Sabatini S., Dell'Uomo M., Manfroni G., Palumbo M., Pannecouque C., De Clercq E., Fravolini A.//J. Med. Chem. 2004. V. 47. No. 22. P. 5567-5578.
68. Richter S.N., Palu G.//Curr. Med. Chem. 2006. V. 13. No. 11. P. 1305-1315.
69. Ebina H., Misawa N., Kanemura Y., Koyanagi Y.//Sci. Rep. 2013. V. 3. P. 2510.
70. Tebas P., Stein D., Tang W.W., Frank I., Wang S.Q., Lee G., Spratt S.K., Surosky R.T., Giedlin M.A., Nichol G., et al.//N. Engl. J. Med. 2014. V. 370. No. 10. P. 901-910.
71. Cho S.W., Kim S., Kim J.M., Kim J.S.//Nat. Biotechnol. 2013. V. 31. No. 3. P. 230-232.
72. Wang W., Ye C., Liu J., Zhang D., Kimata J.T., Zhou P.//PLoS One. 2014. V. 9. No. 12. P. e115987.