Author Correction: ATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective (Cell Death & Differentiation, (2017), 24, 4, (638-648), 10.1038/cdd.2016.158);DATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective

Cell Death and Differentiation

Volumn 24, Issue 4, 2017, Pages 638-648

  Celardo, Ivana ^a   Lehmann, Susann ^a   Costa, Ana C ^a   Loh, Samantha Hy ^a   Miguel Martins, L ^a  

^a MRC TOXICOLOGY UNIT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CARBON; FOLIC ACID; GLYCINE HYDROXYMETHYLTRANSFERASE; GLYCINE HYDROXYMETHYLTRANSFERASE 2; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NAD); PARKIN; RNA; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; METHYLENETETRAHYDROFOLATE DEHYDROGENASE; PINK1 PROTEIN, DROSOPHILA; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CARBON METABOLISM; CONTROLLED STUDY; EPISTASIS; FEMALE; GENE REPRESSION; GENETIC ENHANCEMENT; MALE; MITOCHONDRIAL TOXICITY; MITOCHONDRION; MOTOR DYSFUNCTION; NEUROPROTECTION; NONHUMAN; PARKIN MUTANT (DROSOPHILA); PHENOTYPE; PINK1 MUTANT (DROSOPHILA); PRIORITY JOURNAL; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DROSOPHILA; GENETICS; METABOLISM; MUTAGENESIS; PARKINSON DISEASE; PATHOLOGY; RNA INTERFERENCE;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; FOLIC ACID; GLYCINE HYDROXYMETHYLTRANSFERASE; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP); MITOCHONDRIA; MUTAGENESIS; NEUROPROTECTION; PARKINSON DISEASE; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION;

EID: 85013066207     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/s41418-018-0253-x     Document Type: Erratum

References (25)

1. Kilberg MS, Shan J, Su N. ATF4-dependent transcription mediates signaling of amino acid limitation. Trends Endocrinol Metab 2009; 20: 436-443.
2. Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, et al. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 2000; 6: 1099-1108.
3. Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, et al. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 2003; 11: 619-633.
4. Celardo I, Martins L, Gandhi S. Unravelling mitochondrial pathways to Parkinson's disease. Br J Pharmacol 2014; 171: 1943-1957.
5. Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, et al. Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease. Nat Cell Biol 2014; 16: 157-166.
6. Nikkanen J, Forsstrom S, Euro L, Paetau I, Kohnz RA, Wang L, et al. Mitochondrial DNA replication defects disturb cellular dNTP pools and remodel one-carbon metabolism. Cell Metab 2016; 23: 635-648.
7. Tibbetts AS, Appling DR. Compartmentalization of Mammalian folate-mediated one-carbon metabolism. Annu Rev Nutr 2010; 30: 57-81.
8. Tucker EJ, Hershman SG, Kohrer C, Belcher-Timme CA, Patel J, Goldberger OA, et al. Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation. Cell Metab 2011; 14: 428-434.
9. Di Pietro E, Sirois J, Tremblay ML, MacKenzie RE. Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development. Mol Cell Biol 2002; 22: 4158-4166.
10. Zhang WC, Shyh-Chang N, Yang H, Rai A, Umashankar S, Ma S, et al. Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Cell 2012; 148: 259-272.
11. Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza AL, et al. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science 2012; 336: 1040-1044.
12. Lee GY, Haverty PM, Li L, Kljavin NM, Bourgon R, Lee J, et al. Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes. Cancer Res 2014; 74: 3114-3126.
13. Nilsson R, Jain M, Madhusudhan N, Sheppard NG, Strittmatter L, Kampf C, et al. Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer. Nat Commun 2014; 5: 3128.
14. Kramer A, Green J, Pollard J Jr., Tugendreich S. Causal analysis approaches in Ingenuity Pathway Analysis. Bioinformatics 2014; 30: 523-530.
15. Jousse C, Deval C, Maurin AC, Parry L, Cherasse Y, Chaveroux C, et al. TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway. J Biol Chem 2007; 282: 15851-15861.
16. Celardo I, Costa AC, Lehmann S, Jones C, Wood N, Mencacci NE, et al. Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson's disease. Cell Death Dis 2016; 7: E2271.
17. Lu PD, Harding HP, Ron D. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. J Cell Biol 2004; 167: 27-33.
18. Vattem KM, Wek RC. Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc Natl Acad Sci USA 2004; 101: 11269-11274.
19. Moisoi N, Klupsch K, Fedele V, East P, Sharma S, Renton A, et al. Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response. Cell Death Differ 2009; 16: 449-464.
20. Arner ES, Eriksson S. Mammalian deoxyribonucleoside kinases. Pharmacol Ther 1995; 67: 155-186.
21. Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci USA 2003; 100: 4078-4083.
22. Pimenta de Castro I, Costa AC, Lam D, Tufi R, Fedele V, Moisoi N, et al. Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster. Cell Death Differ 2012; 19: 1308-1316.
23. Whitworth AJ, Theodore DA, Greene JC, Benes H, Wes PD, Pallanck LJ. Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proc Natl Acad Sci USA 2005; 102: 8024-8029.
24. Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003; 100: 9440-9445.
25. Wexler EJ. Photoshop CS3 Extended for Biomedical Research [DVD-ROM and online course]. Lynda. com, Inc. : Ventura, 2008.