YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 7, 2017, Pages 1643-1648

  Taniguchi, Koji ^a,b,c,d,e   Moroishi, Toshiro ^b   De Jong, Petrus R ^f,g   Krawczyk, Michal ^a   Grebbin, Britta Moyo ^h,i   Luo, Huiyan ^a,j   Xu, Rui Hua ^j   Golob Schwarzl, Nicole ^k   Schweiger, Caroline ^k   Wang, Kepeng ^a,b,c,l   Di Caro, Giuseppe ^a,b,c   Feng, Ying ^m   Fearon, Eric R ^m   Raz, Eyal ^f   Kenner, Lukas ^n,o,p   Farin, Henner F ^h,i   Guan, Kun Liang ^b   Haybaeck, Johannes ^k,q   Datz, Christian ^r   Zhang, Kang ^a   Karin, Michael ^a,b,c,s   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Diego   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KYUSHU UNIVERSITY   (Japan)

^e KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^g BURNHAM INSTITUTE   (United States)

^h GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

ⁱ INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

^j SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^k MEDICAL UNIVERSITY OF GRAZ   (Austria)

^l UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^m UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

ⁿ MEDICAL UNIVERSITY OF VIENNA   (Austria)

^o MEDICAL UNIVERSITY OF VIENNA   (Austria)

^p UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^q OTTO VON GUERICKE UNIVERSITY   (Germany)

^r UNIVERSITY OF SALZBURG   (Austria)

^s UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

more..

Author keywords

Adenomatous polyposis coli; Colorectal cancer; IL 6ST gp130; STAT3; YAP

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 11; INTERLEUKIN 6; INTERLEUKIN 6 SIGNAL TRANSDUCER; NOTCH RECEPTOR; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; UNCLASSIFIED DRUG; APC PROTEIN; BETA CATENIN; CTNNB1 PROTEIN, HUMAN; IL6ST PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; YY1AP1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER REGRESSION; CARCINOGENESIS; COLON POLYPOSIS; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; ADULT; AGED; ANIMAL; C57BL MOUSE; COLORECTAL TUMOR; FEMALE; GENETICS; HCT 116 CELL LINE; HEK293 CELL LINE; HT-29 CELL LINE; KNOCKOUT MOUSE; MALE; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ADULT; AGED; ANIMALS; BETA CATENIN; CARCINOGENESIS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYTOKINE RECEPTOR GP130; FEMALE; HCT116 CELLS; HEK293 CELLS; HT29 CELLS; HUMANS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDDLE AGED; MUTATION; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS;

EID: 85013040105     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1620290114     Document Type: Article

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