CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin

Immunity

Volumn 46, Issue 2, 2017, Pages 287-300

  Cheuk, Stanley ^a   Schlums, Heinrich ^a   Gallais Sérézal, Irène ^a,b   Martini, Elisa ^a   Chiang, Samuel C ^a   Marquardt, Nicole ^b   Gibbs, Anna ^a   Detlofsson, Ebba ^a   Introini, Andrea ^a   Forkel, Marianne ^b   Höög, Charlotte ^a   Tjernlund, Annelie ^a   Michaëlsson, Jakob ^b   Folkersen, Lasse ^c   Mjösberg, Jenny ^b   Blomqvist, Lennart ^a   Ehrström, Marcus ^b   Ståhle, Mona ^a,b   Bryceson, Yenan T ^a,d   Eidsmo, Liv ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^d UNIVERSITY OF BERGEN   (Norway)

Author keywords

CD49a; cytotoxicity; granzyme B; IL 15; immunopathology; perforin; psoriasis; Skin; tissue resident T cells; vitiligo

Indexed keywords

ALPHA1 INTEGRIN; BIOLOGICAL MARKER; CD103 ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 15; INTERLEUKIN 17; PERFORIN;

ANTIGEN EXPRESSION; ARTICLE; CELL SPECIFICITY; CELLULAR DISTRIBUTION; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DERMIS; EPIDERMIS; HUMAN; HUMAN TISSUE; INFLAMMATION; MELANOCYTE; MUCOSA; PRIORITY JOURNAL; PSORIASIS; SKIN; SKIN BIOPSY; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TISSUE RESIDENT CD8+ T LYMPHOCYTE; VITILIGO; BIOSYNTHESIS; CD8+ T LYMPHOCYTE; CELL SEPARATION; CONFOCAL MICROSCOPY; CYTOTOXICITY; FLOW CYTOMETRY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION;

CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HUMANS; IMMUNOLOGIC MEMORY; INTEGRIN ALPHA1; LYMPHOCYTE ACTIVATION; MICROSCOPY, CONFOCAL; PSORIASIS; SKIN; T-LYMPHOCYTE SUBSETS; VITILIGO;

EID: 85012927795     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.01.009     Document Type: Article

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