New CRISPR-Cas systems from uncultivated microbes

Nature

Volumn 542, Issue 7640, 2017, Pages 237-241

  Burstein, David ^a   Harrington, Lucas B ^a   Strutt, Steven C ^a   Probst, Alexander J ^a   Anantharaman, Karthik ^a   Thomas, Brian C ^a   Doudna, Jennifer A ^a,b   Banfield, Jillian F ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 1; CRISPR ASSOCIATED PROTEIN 9; DNA FRAGMENT; GUIDE RNA; RIBONUCLEASE III; UNCLASSIFIED DRUG; BACTERIAL RNA; DNA;

BACTERIUM; DNA; ENZYME ACTIVITY; GENETIC ANALYSIS; GENOMICS; IMMUNITY; MICROBIAL COMMUNITY; PROTEIN;

ADAPTIVE IMMUNITY; AMINO ACID SEQUENCE; ARTICLE; CLINICAL RESEARCH; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA CLEAVAGE; DNA SEQUENCE; ESCHERICHIA COLI; GENE EDITING; GENE LOCUS; GENE TARGETING; GENOME SIZE; METAGENOMICS; MICROBIAL COMMUNITY; NONHUMAN; OPEN READING FRAME; PHYLOGENY; POSITION WEIGHT MATRIX; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SECONDARY STRUCTURE; RNA BINDING; RNA INTERFERENCE; RNA PURIFICATION; ARCHAEON; BACTERIUM; BIOTECHNOLOGY; GENE EXPRESSION PROFILING; GENETICS; GENOME; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REPRODUCIBILITY; TRENDS;

ARCHAEA; ESCHERICHIA COLI; NANOARCHAEOTA;

AMINO ACID SEQUENCE; ARCHAEA; BACTERIA; BASE SEQUENCE; BIOTECHNOLOGY; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA; ESCHERICHIA COLI; GENE EXPRESSION PROFILING; GENOME; METAGENOMICS; REPRODUCIBILITY OF RESULTS; RNA, BACTERIAL;

EID: 85012284419     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21059     Document Type: Article

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