Influence of node abundance on signaling network state and dynamics analyzed by mass cytometry

Nature Biotechnology

Volumn 35, Issue 2, 2017, Pages 164-172

  Lun, Xiao Kang ^a   Zanotelli, Vito R T ^a   Wade, James D ^a,b   Schapiro, Denis ^a   Tognetti, Marco ^a,c   Dobberstein, Nadine ^a   Bodenmiller, Bernd ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Emory University   (United States)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; COMPLEX NETWORKS; DISEASE CONTROL; DRUG THERAPY; DYNAMICS; PROTEINS; SIGNAL TRANSDUCTION; SIGNALING;

CELLULAR FUNCTION; EPIDERMAL GROWTH FACTOR RECEPTORS; KEY REGULATORS; OVER-EXPRESSION; SIGNAL TRANSDUCTION NETWORKS; SIGNALING NETWORKS; SIGNALING PROTEINS; SINGLECELL ANALYSIS;

CELL SIGNALING;

CRAF PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT1 PROTEIN; STAT5 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR; PROTEOME;

ANIMAL TISSUE; ARTICLE; BENCHMARKING; CYTOMEGALOVIRUS; CYTOMETRY; EMBRYO; FEEDBACK SYSTEM; FLUORESCENCE ACTIVATED CELL SORTING; GENE OVEREXPRESSION; HUMAN; MASS CYTOMETRY; MOLECULAR DYNAMICS; NODE ABUNDANCE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SIGNALING NETWORK; SINGLE CELL ANALYSIS; STIMULATION; TRANSIENT TRANSFECTION; BIOLOGICAL MODEL; COMPUTER SIMULATION; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; PROCEDURES;

COMPUTER SIMULATION; EPIDERMAL GROWTH FACTOR; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MODELS, BIOLOGICAL; PROTEOME; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 85012154582     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3770     Document Type: Article

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