KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

International Journal of Cancer

Volumn 133, Issue 5, 2013, Pages 1259-1265

  Valtorta, Emanuele ^a   Misale, Sandra ^b,c   Sartore Bianchi, Andrea ^a   Nagtegaal, Iris D ^d   Paraf, François ^e   Lauricella, Calogero ^a   Dimartino, Valentina ^f   Hobor, Sebastijan ^b   Jacobs, Bart ^g   Ercolani, Cristiana ^f   Lamba, Simona ^b,c   Scala, Elisa ^b,c   Veronese, Silvio ^a   Laurent Puig, Pierre ^h   Siena, Salvatore ^a   Tejpar, Sabine ^g   Mottolese, Marcella ^f   Punt, Cornelis J A ⁱ   Gambacorta, Marcello ^a   Bardelli, Alberto ^b,c,j   Di Nicolantonio, Federica ^b,c   more..

^a OSPEDALE NIGUARDA CA GRANDA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c CANDIOLO CANCER INSTITUTE   (Italy)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e LIMOGES UNIVERSITY HOSPITAL   (France)

^f REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^g UNIVERSITY OF LEUVEN   (Belgium)

^h INSERM   (France)

ⁱ UNIVERSITY OF AMSTERDAM   (Netherlands)

^j FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

more..

Author keywords

biomarkers; cetuximab; colorectal cancer; EGFR; EGFR therapy; KRAS; KRAS amplification; panitumumab; resistance

Indexed keywords

CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; PANITUMUMAB;

ARTICLE; CANCER CELL CULTURE; CANCER SCREENING; CANCER TISSUE; CELL VIABILITY; COLORECTAL CANCER; CONTROLLED STUDY; DRUG RESPONSE; DRUG SENSITIVITY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; ONCOGENE K RAS; PREVALENCE; PRIORITY JOURNAL;

BIOMARKERS; CETUXIMAB; COLORECTAL CANCER; EGFR; EGFR THERAPY; KRAS; KRAS AMPLIFICATION; PANITUMUMAB; RESISTANCE;

CELL LINE, TUMOR; COLORECTAL NEOPLASMS; GENE AMPLIFICATION; HUMANS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETROSPECTIVE STUDIES;

EID: 84879240684     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28106     Document Type: Article

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