GM-CSF and IL-3 modulate human monocyte TNF-α production and renewal in in vitro models of trained immunity

Frontiers in Immunology

Volumn 7, Issue JAN, 2017, Pages

  Borriello, Francesco ^a,c   Iannone, Raffaella ^a   Somma, Sarah Di ^a   Loffredo, Stefania ^a   Scamardella, Eloise ^a,d   Galdiero, Maria Rosaria ^a   Varricchi, Gilda ^a   Granata, Francescopaolo ^a   Portella, Giuseppe ^a   Marone, Gianni ^a,b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CNR   (Italy)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

GM CSF; IL 3; Immunometabolism; Inflammation; Innate immune memory; Macrophage; Monocyte; TLR

Indexed keywords

COLONY STIMULATING FACTOR 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INITIATION FACTOR 4E; INTERLEUKIN 1BETA; INTERLEUKIN 3; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 3; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN 2; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR;

ARTICLE; CELL RENEWAL; COLORIMETRY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HUMAN; HUMAN CELL; INNATE IMMUNITY; MONOCYTE; PHAGOCYTOSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION;

EID: 85012065352     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2016.00680     Document Type: Article

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