Nonredundant roles of keratinocyte-derived IL-34 and neutrophil-derived CSF1 in Langerhans cell renewal in the steady state and during inflammation

European Journal of Immunology

Volumn 46, Issue 3, 2016, Pages 552-559

  Wang, Yaming ^a   Bugatti, Mattia ^b   Ulland, Tyler K ^a   Vermi, William ^a,b   Gilfillan, Susan ^a   Colonna, Marco ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Cell development; CSF1; Cytokines; IL 34; Inflammation langerhans cells

Indexed keywords

COLONY STIMULATING FACTOR 1; INTERLEUKIN 34; INTERLEUKIN DERIVATIVE; INTERLEUKIN-34, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL REGENERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATITIS; EMBRYO; EMBRYO DEVELOPMENT; EPIDERMIS; HOMEOSTASIS; INFLAMMATION; KERATINOCYTE; KNOCKOUT MOUSE; LANGERHANS CELL; MONONUCLEAR PHAGOCYTE; MOUSE; MOUSE EMBRYONIC STEM CELL; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SKIN INJURY; STEADY STATE; STEM CELL SELF-RENEWAL; ULTRAVIOLET RADIATION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; EMBRYOLOGY; GENETICS; IMMUNOLOGY; MAMMALIAN EMBRYO; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; EMBRYO, MAMMALIAN; EPIDERMIS; INFLAMMATION; INTERLEUKINS; KERATINOCYTES; LANGERHANS CELLS; MACROPHAGE COLONY-STIMULATING FACTOR; MICE; MICE, KNOCKOUT; NEUTROPHILS; ULTRAVIOLET RAYS;

EID: 84959367081     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201545917     Document Type: Article

References (28)

1. Romani, N., Clausen, B. E. and Stoitzner, P., Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin. Immunol. Rev. 2010. 234: 120-141.
2. Henri, S., Guilliams, M., Poulin, L. F., Tamoutounour, S., Ardouin, L., Dalod, M. and Malissen, B., Disentangling the complexity of the skin dendritic cell network. Immunol. Cell Biol. 2010. 88: 366-375.
3. Kaplan, D. H., In vivo function of Langerhans cells and dermal dendritic cells. Trends Immunol. 2010. 31: 446-451.
4. Clausen, B. E. and Kel, J. M., Langerhans cells: critical regulators of skin immunity? Immunol. Cell Biol. 2010. 88: 351-360.
5. Kaplan, D. H., Kissenpfennig, A. and Clausen, B. E., Insights into Langerhans cell function from Langerhans cell ablation models. Eur. J. Immunol. 2008. 38: 2369-2376.
6. Modi, B. G., Neustadter, J., Binda, E., Lewis, J., Filler, R. B., Roberts, S. J., Kwong, B. Y. et al., Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma. Science 2012. 335: 104-108.
7. Hoeffel, G., Wang, Y., Greter, M., See, P., Teo, P., Malleret, B., Leboeuf, M. et al., Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J. Exp. Med. 2012. 209: 1167-1181.
8. Ginhoux, F. and Merad, M., Ontogeny and homeostasis of Langerhans cells. Immunol. Cell Biol. 2010. 88: 387-392.
9. Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M. and Ley, K., Development of monocytes, macrophages, and dendritic cells. Science 2010. 327: 656-661.
10. Chorro, L., Sarde, A., Li, M., Woollard, K. J., Chambon, P., Malissen, B., Kissenpfennig, A. et al., Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network. J. Exp. Med. 2009. 206: 3089-3100.
11. Merad, M., Sathe, P., Helft, J., Miller, J. and Mortha, A., The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu. Rev. Immunol. 2013. 31: 563-604.
12. Dai, X. M., Ryan, G. R., Hapel, A. J., Dominguez, M. G., Russell, R. G., Kapp, S., Sylvestre, V. et al., Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 2002. 99: 111-120.
13. Ginhoux, F., Tacke, F., Angeli, V., Bogunovic, M., Loubeau, M., Dai, X. M., Stanley, E. R. et al., Langerhans cells arise from monocytes in vivo. Nat. Immunol. 2006. 7: 265-273.
14. Ryan, G. R., Dai, X. M., Dominguez, M. G., Tong, W., Chuan, F., Chisholm, O., Russell, R. G. et al., Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis. Blood 2001. 98: 74-84.
15. Nandi, S., Gokhan, S., Dai, X. M., Wei, S., Enikolopov, G., Lin, H., Mehler, M. F. et al., The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Dev. Biol. 2012. 367: 100-113.
16. Wang, Y. and Colonna, M., Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells. Eur. J. Immunol. 2014. 44: 1575-1581.
17. Wang, Y., Szretter, K. J., Vermi, W., Gilfillan, S., Rossini, C., Cella, M., Barrow, A. D. et al., IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat. Immunol. 2012. 13: 753-760.
18. Greter, M., Lelios, I., Pelczar, P., Hoeffel, G., Price, J., Leboeuf, M., Kundig, T. M. et al., Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia. Immunity 2012. 37: 1050-1060.
19. Cecchini, M. G., Dominguez, M. G., Mocci, S., Wetterwald, A., Felix, R., Fleisch, H., Chisholm, O. et al., Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development 1994. 120: 1357-1372.
20. Bergstresser, P. R., Toews, G. B. and Streilein, J. W., Natural and perturbed distributions of Langerhans cells: responses to ultraviolet light, heterotopic skin grafting, and dinitrofluorobenzene sensitization. J. Invest. Dermatol. 1980. 75: 73-77.
21. Aberer, W., Schuler, G., Stingl, G., Honigsmann, H. and Wolff, K., Ultraviolet light depletes surface markers of Langerhans cells. J. Invest. Dermatol. 1981. 76: 202-210.
22. Kolgen, W., Both, H., van Weelden, H., Guikers, K. L., Bruijnzeel-Koomen, C. A., Knol, E. F., van Vloten, W. A. et al., Epidermal Langerhans cell depletion after artificial ultraviolet B irradiation of human skin in vivo: apoptosis versus migration. J. Invest. Dermatol. 2002. 118: 812-817.
23. Nagao, K., Kobayashi, T., Moro, K., Ohyama, M., Adachi, T., Kitashima, D. Y., Ueha, S. et al., Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin. Nat. Immunol. 2012. 13: 744-752.
24. Sere, K., Baek, J. H., Ober-Blobaum, J., Muller-Newen, G., Tacke, F., Yokota, Y., Zenke, M. et al., Two distinct types of Langerhans cells populate the skin during steady state and inflammation. Immunity 2012. 37: 905-916.
25. Chopin, M., Seillet, C., Chevrier, S., Wu, L., Wang, H., Morse, H. C., 3rd., Belz, G. T. et al., Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks. J. Exp. Med. 2013. 210: 2967-2980.
26. Wei, S., Nandi, S., Chitu, V., Yeung, Y. G., Yu, W., Huang, M., Williams, L. T. et al., Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J. Leukoc. Biol. 2010. 88: 495-505.
27. Santiago, E., Mora, L., Bautista, M., Montesinos, J. J., Martinez, I., Ramos, G., Zambrano, I. R. et al., Granulocyte colony-stimulating factor induces neutrophils to secrete macrophage colony-stimulating factor. Cytokine 2001. 15: 299-304.
28. Santiago-Osorio, E., Mora, L., Bautista, M., Montesinos, J. J., Martinez, I., Ramos-Mandujano, G., Zambrano, R. et al., Sodium caseinate induces secretion of macrophage colony-stimulating factor from neutrophils. Immunobiology 2010. 215: 332-339.