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Volumn 28, Issue 4, 2014, Pages 951-954

Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; INTERLEUKIN 3; MACROPHAGE DERIVED CHEMOKINE; MONOKINE; OSTEOCLAST DIFFERENTIATION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 84898456500     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2013.385     Document Type: Letter
Times cited : (45)

References (14)
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  • 2
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    • Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition
    • DOI 10.1182/blood-2006-05-026112
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  • 3
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    • IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells
    • DOI 10.1182/blood-2003-06-1992
    • Lee JW, Chung HY, Ehrlich LA, Jelinek DF, Callander NS, Roodman GD et al. IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells. Blood 2004; 103: 2308-2315. (Pubitemid 38326251)
    • (2004) Blood , vol.103 , Issue.6 , pp. 2308-2315
    • Lee, J.W.1    Chung, H.Y.2    Ehrlich, L.A.3    Jelinek, D.F.4    Callander, N.S.5    Roodman, G.D.6    Choi, S.J.7
  • 5
    • 84881476071 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF)-1alpha suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction
    • Storti P, Bolzoni M, Donofrio G, Airoldi I, Guasco D, Toscani D et al. Hypoxia-inducible factor (HIF)-1alpha suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction. Leukemia 2013; 27: 1697-1706.
    • (2013) Leukemia , vol.27 , pp. 1697-1706
    • Storti, P.1    Bolzoni, M.2    Donofrio, G.3    Airoldi, I.4    Guasco, D.5    Toscani, D.6
  • 7
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    • Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; No alterations post-lenalidomide and dexamethasone therapy
    • Terpos E, Kastritis E, Christoulas D, Gkotzamanidou M, Eleutherakis-Papaiakovou E, Kanellias N et al. Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy. Ann Oncol 2012; 23: 2681-2686.
    • (2012) Ann Oncol , vol.23 , pp. 2681-2686
    • Terpos, E.1    Kastritis, E.2    Christoulas, D.3    Gkotzamanidou, M.4    Eleutherakis-Papaiakovou, E.5    Kanellias, N.6
  • 8
    • 77950438331 scopus 로고    scopus 로고
    • Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease
    • Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S et al. Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proc Natl Acad Sci USA 2010; 107: 5124-5129.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5124-5129
    • Vallet, S.1    Mukherjee, S.2    Vaghela, N.3    Hideshima, T.4    Fulciniti, M.5    Pozzi, S.6
  • 10
    • 77950533566 scopus 로고    scopus 로고
    • A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys
    • Lotinun S, Pearsall RS, Davies MV, Marvell TH, Monnell TE, Ucran J et al. A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys. Bone 2010; 46: 1082-1088.
    • (2010) Bone , vol.46 , pp. 1082-1088
    • Lotinun, S.1    Pearsall, R.S.2    Davies, M.V.3    Marvell, T.H.4    Monnell, T.E.5    Ucran, J.6
  • 11
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    • Lenalidomide in combination with an activin A-neutralizing antibody: Preclinical rationale for a novel anti-myeloma strategy
    • Scullen T, Santo L, Vallet S, Fulciniti M, Eda H, Cirstea D et al. Lenalidomide in combination with an activin A-neutralizing antibody: preclinical rationale for a novel anti-myeloma strategy. Leukemia 2013; 27: 1715-1721.
    • (2013) Leukemia , vol.27 , pp. 1715-1721
    • Scullen, T.1    Santo, L.2    Vallet, S.3    Fulciniti, M.4    Eda, H.5    Cirstea, D.6
  • 13
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    • Inhibin suppresses and activin stimulates osteoblastogenesis and osteoclastogenesis in murine bone marrow cultures
    • DOI 10.1210/en.143.1.74
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    • (2002) Endocrinology , vol.143 , Issue.1 , pp. 74-83
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.