Inorganic mercury prevents the differentiation of SH-SY5Y cells: Amyloid precursor protein, microtubule associated proteins and ROS as potential targets

Journal of Trace Elements in Medicine and Biology

Volumn 41, Issue , 2017, Pages 119-128

  Chan, Miguel Chin ^a,b   Bautista, Elizabeth ^a,c   Alvarado Cruz, Isabel ^a   Quintanilla Vega, Betzabet ^a   Segovia, José ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DE CAMPECHE   (Mexico)

^c UNIVERSIDAD ANÁHUAC   (Mexico)

Author keywords

Amyloid precursor protein; Inorganic mercury; Neuronal differentiation; Neurotoxicity; NO; ROS

Indexed keywords

AMYLOID PROTEIN; BETA TUBULIN; BETA TUBULIN III; DIMETHYLARGININASE; INORGANIC MERCURY; MERCURY; METHYLMERCURY; MICROTUBULE ASSOCIATED PROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; TAU PROTEIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN;

ARTICLE; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; MTT ASSAY; NERVE CELL DIFFERENTIATION; NERVE CELL STIMULATION; NEURITE; NEUROTOXICITY; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN TARGETING; SH SY5Y CELL; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; CELL DIFFERENTIATION; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; STRUCTURE ACTIVITY RELATION;

AMYLOID BETA-PROTEIN PRECURSOR; CELL DIFFERENTIATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MERCURY; MICROTUBULE-ASSOCIATED PROTEINS; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; TRETINOIN;

EID: 85012031309     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2017.02.002     Document Type: Article

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