Superoxide anion radical (O 2 -) degrades methylmercury to inorganic mercury in human astrocytoma cell line (CCF-STTG1)

Chemico-Biological Interactions

Volumn 239, Issue , 2015, Pages 46-55

  Mailloux, Ryan J ^a   Yumvihoze, Emmanuel ^a   Chan, Hing Man ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Inorganic mercury; Methylmercury; Neurotoxicity; Oxidative stress; Reactive oxygen species; Superoxide

Indexed keywords

HYDROGEN PEROXIDE; INORGANIC COMPOUND; INORGANIC MERCURY; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN CHLORIDE; METHYLMERCURY; OXYGEN; OXYGEN RADICAL; PARAQUAT; PORPHYRIN DERIVATIVE; SUPEROXIDE ANION RADICAL; UNCLASSIFIED DRUG; XANTHINE; XANTHINE OXIDASE; MERCURY; METHYLMERCURY DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ARTICLE; ASTROCYTOMA CELL LINE; BIOTRANSFORMATION; CCF STTG1 CELL LINE; CELL DEATH; CELL LEVEL; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGRADATION KINETICS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUROTOXICITY; OXIDATIVE STRESS; ASTROCYTOMA; CENTRAL NERVOUS SYSTEM NEOPLASMS; DRUG EFFECTS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ASTROCYTOMA; CELL DEATH; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM NEOPLASMS; HUMANS; HYDROGEN PEROXIDE; MERCURY; METHYLMERCURY COMPOUNDS; OXIDATIVE STRESS; PARAQUAT; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES; XANTHINE; XANTHINE OXIDASE;

EID: 84933567296     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.06.028     Document Type: Article

References (40)

1. S.D. Siciliano, and D.R. Lean Methyltransferase: an enzyme assay for microbial methylmercury formation in acidic soils and sediments Environ. Toxicol. Chem./SETAC 21 2002 1184 1190
2. S.D. Siciliano, N.J. O'Driscoll, R. Tordon, J. Hill, S. Beauchamp, and D.R. Lean Abiotic production of methylmercury by solar radiation Environ. Sci. Technol. 39 2005 1071 1077
3. V. Celo, D.R. Lean, and S.L. Scott Abiotic methylation of mercury in the aquatic environment Sci. Total Environ. 368 2006 126 137
4. H.K. Kong, M.H. Wong, H.M. Chan, and S.C. Lo Chronic exposure of adult rats to low doses of methylmercury induced a state of metabolic deficit in the somatosensory cortex J. Proteome Res. 12 2013 5233 5245
5. A. Yasutake, and K. Hirayama Evaluation of methylmercury biotransformation using rat liver slices Arch. Toxicol. 75 2001 400 406
6. M. Aschner, N.B. Eberle, S. Goderie, and H.K. Kimelberg Methylmercury uptake in rat primary astrocyte cultures: the role of the neutral amino acid transport system Brain Res. 521 1990 221 228
7. M. Aschner, and J.L. Aschner Mercury neurotoxicity: mechanisms of blood-brain barrier transport Neurosci. Biobehav. Rev. 14 1990 169 176
8. R.E. Hoffmeyer, S.P. Singh, C.J. Doonan, A.R. Ross, R.J. Hughes, I.J. Pickering, and G.N. George Molecular mimicry in mercury toxicology Chem. Res. Toxicol. 19 2006 753 759
9. S. Ceccatelli, E. Dare, and M. Moors Methylmercury-induced neurotoxicity and apoptosis Chem. Biol. Interact. 188 2010 301 308
10. T. Yamazaki, M. Yamamoto, Y. Ishihara, S. Komatsu, E. Munetsuna, M. Onizaki, A. Ishida, S. Kawato, and T. Mukuda De novo synthesized estradiol protects against methylmercury-induced neurotoxicity in cultured rat hippocampal slices PLoS ONE 8 2013 e55559
11. K. Sokolowski, M. Obiorah, K. Robinson, E. McCandlish, B. Buckley, and E. DiCicco-Bloom Neural stem cell apoptosis after low-methylmercury exposures in postnatal hippocampus produce persistent cell loss and adolescent memory deficits Dev. Neurobiol. 73 2013 936 949
12. P. Kaur, M. Aschner, and T. Syversen Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress Toxicology 230 2007 164 177
13. E. Dare, W. Li, B. Zhivotovsky, X. Yuan, and S. Ceccatelli Methylmercury and H(2)O(2) provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis Free Radical Biol. Med. 30 2001 1347 1356
14. T.L. Limke, and W.D. Atchison Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells Toxicol. Appl. Pharmacol. 178 2002 52 61
15. Z. Yin, E. Lee, M. Ni, H. Jiang, D. Milatovic, L. Rongzhu, M. Farina, J.B. Rocha, and M. Aschner Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen Neurotoxicology 32 2011 291 299
16. P.M. Rodier Developing brain as a target of toxicity Environ. Health Perspect. 103 Suppl 6 1995 73 76
17. J.C. Hansen, E. Reske-Nielsen, O. Thorlacius-Ussing, J. Rungby, and G. Danscher Distribution of dietary mercury in a dog. Quantitation and localization of total mercury in organs and central nervous system Sci. Total Environ. 78 1989 23 43
18. A.M. Shapiro, and H.M. Chan Characterization of demethylation of methylmercury in cultured astrocytes Chemosphere 74 2008 112 118
19. A. Yasutake, A. Nakano, K. Miyamoto, and K. Eto Chronic effects of methylmercury in rats. I. Biochemical aspects Tohoku J. Exp. Med. 182 1997 185 196
20. I. Suda, S. Totoki, and H. Takahashi Degradation of methyl and ethyl mercury into inorganic mercury by oxygen free radical-producing systems: involvement of hydroxyl radical Arch. Toxicol. 65 1991 129 134
21. T. Zhang, and H. Hsu-Kim Photolytic degradation of methylmercury enhanced by binding to natural organic ligands Nat. Geosci. 3 2010 473 476
22. R.J. Mailloux, S.L. McBride, and M.E. Harper Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics Trends Biochem. Sci. 38 2013 592 602
23. M. Nagano, A. Yasutake, and K. Miura Demethylation of methylmercury in human neuroblastoma, glioblastoma, and liver cells J. Health Sci. 56 2010 326 330
24. J. Chen, S.C. Rogers, and M. Kavdia Analysis of kinetics of dihydroethidium fluorescence with superoxide using xanthine oxidase and hypoxanthine assay Ann. Biomed. Eng. 41 2013 327 337
25. K.M. Robinson, M.S. Janes, M. Pehar, J.S. Monette, M.F. Ross, T.M. Hagen, M.P. Murphy, and J.S. Beckman Selective fluorescent imaging of superoxide in vivo using ethidium-based probes Proc. Natl. Acad. Sci. U.S.A 103 2006 15038 15043
26. S. Goldstein, and G. Czapski Mannitol as an OH· scavenger in aqueous solutions and in biological systems Int. J. Radiat. Biol. (Related studies in Physics, Chemistry, and Medicine) 46 1984 725 729
27. J. Lemire, C. Auger, R. Mailloux, and V.D. Appanna Mitochondrial lactate metabolism is involved in antioxidative defense in human astrocytoma cells J. Neurosci. Res. 92 2014 464 475
28. J. Lemire, R.J. Mailloux, and V.D. Appanna Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1) PLoS ONE 3 2008 e1550
29. B.D. Barst, C.R. Hammerschmidt, M.M. Chumchal, D.C. Muir, J.D. Smith, A.P. Roberts, T.R. Rainwater, and P.E. Drevnick Determination of mercury speciation in fish tissue with a direct mercury analyzer Environ. Toxicol. Chem./SETAC 32 2013 1237 1241
30. B. Kalyanaraman, V. Darley-Usmar, K.J. Davies, P.A. Dennery, H.J. Forman, M.B. Grisham, G.E. Mann, K. Moore, L.J. Roberts 2nd, and H. Ischiropoulos Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations Free Radical Biol. Med. 52 2012 1 6
31. R.J. Mailloux, A. Fu, C. Robson-Doucette, E.M. Allister, M.B. Wheeler, R. Screaton, and M.E. Harper Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion J. Biol. Chem. 287 2012 39673 39685
32. H.M. Cocheme, and M.P. Murphy Complex I is the major site of mitochondrial superoxide production by paraquat J. Biol. Chem. 283 2008 1786 1798
33. T.M. Paravicini, and R.M. Touyz NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities Diabetes Care 31 Suppl 2 2008 S170 S180
34. K. Eto, A. Yasutake, K. Miyamoto, H. Tokunaga, and Y. Otsuka Chronic effects of methylmercury in rats. II. Pathological aspects Tohoku J. Exp. Med. 182 1997 197 205
35. M.P. Murphy How mitochondria produce reactive oxygen species Biochem. J. 417 2009 1 13
36. R.J. Mailloux, M. Florian, Q. Chen, J. Yan, I. Petrov, M.C. Coughlan, M. Laziyan, D. Caldwell, M. Lalande, D. Patry, C. Gagnon, K. Sarafin, J. Truong, H.M. Chan, N. Ratnayake, N. Li, W.G. Willmore, and X. Jin Exposure to a northern contaminant mixture (NCM) alters hepatic energy and lipid metabolism exacerbating hepatic steatosis in obese JCR rats PLoS ONE 9 2014 e106832
37. R.J. Mailloux Teaching the fundamentals of electron transfer reactions in mitochondria and the production and detection of reactive oxygen species Redox Biol. 4 2015 381 398
38. J.S. Charleston, R.L. Body, R.P. Bolender, N.K. Mottet, M.E. Vahter, and T.M. Burbacher Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure Neurotoxicology 17 1996 127 138
39. J.W. Allen, G. Shanker, K.H. Tan, and M. Aschner The consequences of methylmercury exposure on interactive functions between astrocytes and neurons Neurotoxicology 23 2002 755 759
40. M. Korbas, J.L. O'Donoghue, G.E. Watson, I.J. Pickering, S.P. Singh, G.J. Myers, T.W. Clarkson, and G.N. George The chemical nature of mercury in human brain following poisoning or environmental exposure ACS Chem. Neurosci. 1 2010 810 818