The in vitro effects of Trolox on methylmercury-induced neurotoxicity

Toxicology

Volumn 276, Issue 1, 2010, Pages 73-78

  Kaur, Parvinder ^a   Evje, Lars ^a   Aschner, Michael ^b,c   Syversen, Tore ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell cultures; In vitro; Neurotoxicity; Reactive oxygen species; Reduced glutathione; Trolox

Indexed keywords

GLUTATHIONE; METHYLMERCURY; REACTIVE OXYGEN METABOLITE; TROLOX C;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; MITOCHONDRION; NERVE CELL; NEUROTOXICITY; PRIORITY JOURNAL;

EID: 77955659875     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.07.006     Document Type: Article

References (55)

1. Ali S.F., LeBel C.P., Bondy S.C. Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity. Neurotoxicology 1992, 13:637-648.
2. Barclay L.R., Vinqvist M.R. Membrane peroxidation: inhibiting effects of water-soluble antioxidants on phospholipids of different charge types. Free Radic. Biol. Med. 1994, 16:779-788.
3. Cadenas E., Merenyi G., Lind J. Pulse radiolysis study on the reactivity of Trolox C phenoxyl radical with superoxide anion. FEBS Lett. 1989, 253:235-238.
4. Carmichael J., DeGraff W.G., Gazdar A.F., Minna J.D., Mitchell J.B. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity. Cancer Res. 1987, 47:943-946.
5. Carty A.J., Malone S.F. The chemistry of mercury in biological systems. The Biogeochemistry of Mercury in the Environment 1979, 433-479. Elsevier/North-Holland Biomedical Press, Amsterdam. J.O. Nrigau (Ed.).
6. Choi B.H., Lapham L.W., Amin-Zaki L., Saleem T. Abnormal neuronal migration, deranged cerebral cortical organization, and diffuse white matter astrocytosis of human fetal brain: a major effect of methylmercury poisoning in utero. J. Neuropathol. Exp. Neurol. 1978, 37:719-733.
7. Choi B.H., Yee S., Robles M. The effects of glutathione glycoside in methyl mercury poisoning. Toxicol. Appl. Pharmacol. 1996, 141:357-364.
8. Clarkson T.W., Magos L., Myers G.J. The toxicology of mercury-current exposures and clinical manifestations. N. Engl. J. Med. 2003, 349:1731-1737.
9. Davidson P.W., Myers G.J., Cox C., Axtell C., Shamlaye C., Sloane-Reeves J., Cernichiari E., Needham L., Choi A., Wang Y., Berlin M., Clarkson T.W. Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: outcomes at 66 months of age in the Seychelles Child Development Study. JAMA 1998, 280:701-707.
10. Davies M.J., Fomi L.G., Willson R.L. Vitamin E analogue Trolox C.E. s. r. and pulse-radiolysis studies of free-radical reactions. Biochem. J. 1988, 255:513-522.
11. Doba T., Burton G.W., Ingold K.U. Antioxidant and co-antioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous muitilamellar phospholipid liposomes. Biochim. Biophys. Acta 1985, 835:298-303.
12. Eto K. Pathology of Minamata disease. Toxicol. Pathol. 1997, 25:614-623.
13. Frankel E.N. Antioxidants. Lipid oxidation. 2005, 209-258. The Oily Press, Bridgwater, United Kingdom. E.N. Frankel (Ed.).
14. Garcia J.J., Martinez-Ballarin E., Robinson M., Allue J.L., Reiter R.J., Osuna C., Acuna-Castroviejo D. Protective effect of beta-carbolines and other antioxidants on lipid peroxidation due to hydrogen peroxide in rat brain homogenates. Neurosci. Lett. 2000, 294:1-4.
15. Grandjean P., Weihe P., White R.F., Debes F., Araki S., Yokoyama K., Murata K., Sorensen N., Dahl R., Jorgensen P.J. Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury. Neurotoxicol. Teratol. 1997, 19:417-428.
16. Halliwell B., Gutteridge J.M., Cross C.E. Free radicals, antioxidants, and human diseases: where are we now? J. Lab. Clin. Med. 1992, 119:598-620.
17. Hibbeln J.R., Davis J.M., Steer C., Emmett P., Rogers I., Williams C., Golding J. Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study. Lancet 2007, 369:578-585.
18. Hughes W.L. A physicochemical rationale for the biological activity of mercury and its compounds. Ann. N. Y. Acad. Sci. 1957, 65:454-460.
19. Hunter D., Russell D.S. Focal cerebellar and cerebellar atrophy in a human subject due to organic mercury compounds. J. Neurol. Neurosurg. Psychiatr. 1954, 17:235-241.
20. JECFA, 1978. Evaluation of certain food additives and contaminants. Twenty-second Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 631.
21. Kamps L.R., Carr R., Miller H. Total mercury-monomethylmercury content of several species of fish. Bull. Environ. Contam. Toxicol. 1972, 8:273-279.
22. Kato S., Negishi K., Mawatari K., Kuo C.H. A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion. Neuroscience 1992, 48:903-914.
23. Kaur P., Aschner M., Syversen T. Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes. Neurotoxicology 2006, 27:492-500.
24. Kaur P., Schulz K., Aschner M., Syversen T. Role of docosahexaenoic acid in modulating methylmercury-induced neurotoxicity. Toxicol. Sci. 2007, 100:423-432.
25. Keown-Eyssen G.E., Ruedy J., Neims A. Methyl mercury exposure in northern Quebec. II. Neurologic findings in children. Am. J. Epidemiol. 1983, 118:470-479.
26. Kjellstrom, T., Kennedy, P., Wallis, S., Mantell, C., 1986. Physical and mental development of children with prenatal exposure to mercury from fish. Stage I: Preliminary tests at age 4. National Swedish Environmental Protection Board Report, Solna, Sweden.
27. Kjellstrom, T., Kennedy, P., Wallis, S., Stewart, A., Friberg, L., Lind, B., Wutherspoon, T., Mantell, C., 1989. Physical and mental development of children with prenatal exposure to mercury from fish. Stage II: Interviews and psychological tests at age 6. National Swedish Environmental Protection Board Report No. 3642, Solna, Sweden.
28. Lee H., Lee K., Jung J.K., Cho J., Theodorakis E.A. Synthesis and evaluation of 6-hydroxy-7-methoxy-4-chromanone-and chroman-2-carboxamides as antioxidants. Bioorgan. Med. Chem. Lett. 2005, 15:2745-2748.
29. Lowry O.H., Rosenbrough N.J., Farr A.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951, 193:265-275.
30. Malcolm C.S., Benwell K.R., Lamb H., Bebbington D., Porter R.H. Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells. Free Radic. Biol. Med. 2000, 28:102-107.
31. Marsh D.O., Turner M.D., Smith J.C., Allen P., Richdale N. Fetal methylmercury study in a Peruvian fish-eating population. Neurotoxicology 1995, 16:717-726.
32. Massey K.D., Burton K.P. Free radical damage in neonatal rat cardiac myocyte cultures: effects of alpha-tocopherol, Trolox and phytol. Free Radic. Biol. Med. 1990, 8:449-458.
33. Mozaffarian D., Rimm E.B. Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA 2006, 296:1885-1899.
34. Murphy T.H., Miyamoto M., Sastre A., Schnaar R.L., Coyle J.T. Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 1989, 2:1547-1558.
35. Myers G.J., Davidson P.W., Shamlaye C.F., Axtell C.D., Cernichiari E., Choisy O., Choi A., Cox C., Clarkson T.W. Effects of prenatal methylmercury exposure from a high fish diet on developmental milestones in the Seychelles Child Development Study. Neurotoxicology 1997, 18:819-829.
36. Myers G.J., Davidson P.W., Strain J.J. Nutrient and methyl mercury exposure from consuming fish. J. Nutr. 2007, 137:2805-2808.
37. Nagashima K. A review of experimental methylmercury toxicity in rats: neuropathology and evidence for apoptosis. Toxicol. Pathol. 1997, 25:624-631.
38. National Research Council Toxicological Effects of Methyl mercury. Board on Environment Studies and Toxicology 2000, The National Academy Press, Washington, DC.
39. NIEHS, 1999. Report of the workshop on the scientific issues relevant to assessment of health effects from exposure to methylmercury. Organized by Committee on Environmental and Natural Resources (CENR), Office of Science and Technology Policy (OSTP) and The White House. Raleigh, NC.
40. Oken E., Wright R.O., Kleinman K.P., Bellinger D., Amarasiriwardena C.J., Hu H., Rich-Edwards J.W., Gillman M.W. Maternal fish consumption, hair mercury, and infant cognition in a U.S. Cohort. Environ. Health Perspect. 2005, 113:1376-1380.
41. Passi S., Cataudella S., Marco P.D., Simone F.D., Rastrelli L. Fatty acid composition and antioxidant levels in muscle tissue of different Mediterranean marine species of fish and shellfish. J. Agric. Food Chem. 2002, 50:7314-7322.
42. Persoon-Rothert M., Egas-Kenniphaas J.M., Van der Valk-Kokshoorn E.J., Mauve I., Van der Laarse A. Prevention of cumene hydroperoxide induced oxidative stress in cultured neonatal rat myocytes by scavengers and enzyme inhibitors. J. Mol. Cell Cardiol. 1990, 22:1147-1155.
43. Raspor P., Pleniscar S., Gazdag Z., Pesti M., Miklavcic M., Lah B., Logar-Marinsek R., Poljsak B. Prevention of intracellular oxidation in yeast: the role of vitamin E analogue, Trolox (6-hydroxy-2,5,7,8-tetramethylkroman-2-carboxyl acid). Cell Biol. Int. 2005, 29:57-63.
44. Sagach V.F., Scrosati M., Fielding J., Rossoni G., Galli C., Visioli F. The water-soluble vitamin E analogue Trolox protects against ischaemia/reperfusion damage in vitro and ex vivo. A comparison with vitamin E. Pharmacol. Res. 2002, 45:435-439.
45. Sanfeliu C., Sebastia J., Ki S.U. Methylmercury neurotoxicity in cultures of human neurons, astrocytes, neuroblastoma cells. Neurotoxicology 2001, 22:317-327.
46. Sarafian T.A. Methylmercury-induced generation of free radicals: biological implications. Met. Ions. Biol. Syst. 1999, 36:415-444.
47. Sarafian T.A., Vartavarian L., Kane D.J., Bredesen D.E., Verity M.A. bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line. Toxicol. Lett. 1994, 74:149-155.
48. Sarafian T., Verity M.A. Oxidative mechanisms underlying methyl mercury neurotoxicity. Int. J. Dev. Neurosci. 1991, 9:147-153.
49. Spry D.J., Wiener J.G. Metal bioavailability and toxicity to fish in low-alkalinity lakes: a critical review. Environ. Pollut. 1991, 71:243-304.
50. Suttorp N., Toepfer W., Roka L. Antioxidant defense mechanisms of endothelial cells: glutathione redox cycle versus catalase. Am. J. Physiol. 1986, 251:C671-C680.
51. Takeuchi T. Pathology of Minamata disease. With special reference to its pathogenesis. Acta Pathol. Jpn. 1982, 32:73-99.
52. Usuki F., Yasutake A., Umehara F., Tokunaga H., Matsumoto M., Eto K., Ishiura S., Higuchi I. In vivo protection of a water-soluble derivative of vitamin E, Trolox, against methylmercury-intoxication in the rat. Neurosci. Lett. 2001, 304:199-203.
53. Vijayalakshmi K., Sood P.P. Ameliorative capacities of vitamins and monothiols post therapy in the restoration of methylmercury altered glutathione metabolism. Cell Mol. Biol. (Noisy-le-grand) 1994, 40:211-224.
54. Wu T.W., Hashimoto N., Wu J., Carey D., Li R.K., Mickle D.A., Weisel R.D. The cytoprotective effect of Trolox demonstrated with three types of human cells. Biochem. Cell Biol. 1990, 68:1189-1194.
55. Yee S., Choi B.H. Oxidative stress in neurotoxic effects of methylmercury poisoning. Neurotoxicology 1996, 17:17-26.