CRISPR/Cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method

Scientific Reports

Volumn 7, Issue , 2017, Pages

  Ma, Xiaolong ^a,b   Chen, Chao ^b   Veevers, Jennifer ^b   Zhou, XinMin ^a   Ross, Robert S ^b,c   Feng, Wei ^b   Chen, Ju ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE;

AMINO ACID SUBSTITUTION; ANIMAL; CRISPR CAS SYSTEM; GENE KNOCKOUT; GENETICS; GENOME; KNOCKOUT MOUSE; METABOLISM; MOLECULAR CLONING; MUTANT MOUSE STRAIN; NUCLEOTIDE SEQUENCE;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; CRISPR-CAS SYSTEMS; GENE KNOCKOUT TECHNIQUES; GENOME; MICE, KNOCKOUT; MICE, MUTANT STRAINS; PROTEIN KINASES;

EID: 85011899852     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep42244     Document Type: Article

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