Hepatic expression of adenovirus 36 E4ORF1 improves glycemic control and promotes glucose metabolism through AKT activation

Diabetes

Volumn 66, Issue 2, 2017, Pages 358-371

  McMurphy, Travis B ^a,b   Huang, Wei ^a,b   Xiao, Run ^a,b   Liu, Xianglan ^a,b   Dhurandhar, Nikhil V ^c   Cao, Lei ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENO ASSOCIATED VIRUS VECTOR; E4ORF1 PROTEIN; GLUCOSE; INSULIN; PROTEIN KINASE B; RECOMBINANT E4ORF1 PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRAL PROTEIN; GLUCOSE BLOOD LEVEL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET INDUCED OBESITY; FEMALE; FLUORESCENCE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLYCEMIC CONTROL; HUMAN ADENOVIRUS 36; HUMAN ADENOVIRUS 5; HUMAN ADENOVIRUS C; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; LIVER; MALE; MOUSE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; VIRAL GENE DELIVERY SYSTEM; VIRUS REPLICATION; VIRUS STRAIN; WILD TYPE; ADIPOCYTE; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; DIABETES MELLITUS; GENETICS; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; METABOLISM; MOUSE MUTANT; OBESITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; WESTERN BLOTTING;

ADENOVIRUS E4 PROTEINS; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; DIABETES MELLITUS; FEMALE; GLUCOSE; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; INSULIN; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MUSCLE, SKELETAL; OBESITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 85011661169     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db16-0876     Document Type: Article

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