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Volumn 7, Issue 10, 2012, Pages

E4orf1 Improves Lipid and Glucose Metabolism in Hepatocytes: A Template to Improve Steatosis & Hyperglycemia

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; CELL PROTEIN; CYCLIC AMP; DEXAMETHASONE; GLUCAGON; PALMITIC ACID; PROTEIN E4ORF1; UNCLASSIFIED DRUG;

EID: 84867878591     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047813     Document Type: Article
Times cited : (35)

References (24)
  • 1
    • 0344874201 scopus 로고    scopus 로고
    • Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease
    • Diraison F, Moulin P, Beylot M, (2003) Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease. Diabetes Metab 29: 478-485.
    • (2003) Diabetes Metab , vol.29 , pp. 478-485
    • Diraison, F.1    Moulin, P.2    Beylot, M.3
  • 2
    • 34547911800 scopus 로고    scopus 로고
    • The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
    • Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, et al. (2007) The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proc Natl Acad Sci U S A 104: 12587-12594.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12587-12594
    • Petersen, K.F.1    Dufour, S.2    Savage, D.B.3    Bilz, S.4    Solomon, G.5
  • 3
    • 33644827082 scopus 로고    scopus 로고
    • Overproduction of large VLDL particles is driven by increased liver fat content in man
    • Adiels M, Taskinen MR, Packard C, Caslake MJ, Soro-Paavonen A, et al. (2006) Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia 49: 755-765.
    • (2006) Diabetologia , vol.49 , pp. 755-765
    • Adiels, M.1    Taskinen, M.R.2    Packard, C.3    Caslake, M.J.4    Soro-Paavonen, A.5
  • 4
    • 36749082168 scopus 로고    scopus 로고
    • Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance
    • Zhang D, Liu ZX, Choi CS, Tian L, Kibbey R, et al. (2007) Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance. Proc Natl Acad Sci U S A 104: 17075-17080.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17075-17080
    • Zhang, D.1    Liu, Z.X.2    Choi, C.S.3    Tian, L.4    Kibbey, R.5
  • 5
    • 70349326750 scopus 로고    scopus 로고
    • Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
    • Fabbrini E, Magkos F, Mohammed BS, Pietka T, Abumrad NA, et al. (2009) Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc Natl Acad Sci U S A 106: 15430-15435.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 15430-15435
    • Fabbrini, E.1    Magkos, F.2    Mohammed, B.S.3    Pietka, T.4    Abumrad, N.A.5
  • 6
    • 75449094816 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications
    • Fabbrini E, Sullivan S, Klein S, (2010) Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology 51: 679-689.
    • (2010) Hepatology , vol.51 , pp. 679-689
    • Fabbrini, E.1    Sullivan, S.2    Klein, S.3
  • 7
    • 42949178538 scopus 로고    scopus 로고
    • Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects
    • Korenblat KM, Fabbrini E, Mohammed BS, Klein S, (2008) Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology 134: 1369-1375.
    • (2008) Gastroenterology , vol.134 , pp. 1369-1375
    • Korenblat, K.M.1    Fabbrini, E.2    Mohammed, B.S.3    Klein, S.4
  • 8
    • 34548787759 scopus 로고    scopus 로고
    • Metabolic correlates of nonalcoholic fatty liver in women and men
    • Vega GL, Chandalia M, Szczepaniak LS, Grundy SM, (2007) Metabolic correlates of nonalcoholic fatty liver in women and men. Hepatology 46: 716-722.
    • (2007) Hepatology , vol.46 , pp. 716-722
    • Vega, G.L.1    Chandalia, M.2    Szczepaniak, L.S.3    Grundy, S.M.4
  • 9
    • 20944450486 scopus 로고    scopus 로고
    • Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
    • Bugianesi E, Gastaldelli A, Vanni E, Gambino R, Cassader M, et al. (2005) Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms. Diabetologia 48: 634-642.
    • (2005) Diabetologia , vol.48 , pp. 634-642
    • Bugianesi, E.1    Gastaldelli, A.2    Vanni, E.3    Gambino, R.4    Cassader, M.5
  • 10
    • 0036312905 scopus 로고    scopus 로고
    • Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
    • Seppala-Lindroos A, Vehkavaara S, Hakkinen AM, Goto T, Westerbacka J, et al. (2002) Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 87: 3023-3028.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3023-3028
    • Seppala-Lindroos, A.1    Vehkavaara, S.2    Hakkinen, A.M.3    Goto, T.4    Westerbacka, J.5
  • 12
    • 18244364864 scopus 로고    scopus 로고
    • NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
    • Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, et al. (2002) NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 35: 373-379.
    • (2002) Hepatology , vol.35 , pp. 373-379
    • Chitturi, S.1    Abeygunasekera, S.2    Farrell, G.C.3    Holmes-Walker, J.4    Hui, J.M.5
  • 13
    • 33748179703 scopus 로고    scopus 로고
    • Weight loss as a treatment for nonalcoholic fatty liver disease
    • Clark JM, (2006) Weight loss as a treatment for nonalcoholic fatty liver disease. J Clin Gastroenterol 40 (Suppl 1):: S39-43.
    • (2006) J Clin Gastroenterol , vol.40 , Issue.SUPPL. 1
    • Clark, J.M.1
  • 14
    • 77953444310 scopus 로고    scopus 로고
    • Treatment options for nonalcoholic fatty liver disease
    • Lam B, Younossi ZM, (2010) Treatment options for nonalcoholic fatty liver disease. Therap Adv Gastroenterol 3: 121-137.
    • (2010) Therap Adv Gastroenterol , vol.3 , pp. 121-137
    • Lam, B.1    Younossi, Z.M.2
  • 16
    • 52749091092 scopus 로고    scopus 로고
    • Metabolically favorable remodeling of human adipose tissue by human adenovirus type 36
    • Rogers PM, Mashtalir N, Rathod MA, Dubuisson O, Wang Z, et al. (2008) Metabolically favorable remodeling of human adipose tissue by human adenovirus type 36. Diabetes 57: 2321-2331.
    • (2008) Diabetes , vol.57 , pp. 2321-2331
    • Rogers, P.M.1    Mashtalir, N.2    Rathod, M.A.3    Dubuisson, O.4    Wang, Z.5
  • 17
    • 48249131328 scopus 로고    scopus 로고
    • Human adenovirus type 36 enhances glucose uptake in diabetic and nondiabetic human skeletal muscle cells independent of insulin signaling
    • Wang ZQ, Cefalu WT, Zhang XH, Yu Y, Qin J, et al. (2008) Human adenovirus type 36 enhances glucose uptake in diabetic and nondiabetic human skeletal muscle cells independent of insulin signaling. Diabetes 57: 1805-1813.
    • (2008) Diabetes , vol.57 , pp. 1805-1813
    • Wang, Z.Q.1    Cefalu, W.T.2    Zhang, X.H.3    Yu, Y.4    Qin, J.5
  • 18
  • 21
    • 70449927254 scopus 로고    scopus 로고
    • Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein
    • Erion DM, Ignatova ID, Yonemitsu S, Nagai Y, Chatterjee P, et al. (2009) Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein. Cell Metab 10: 499-506.
    • (2009) Cell Metab , vol.10 , pp. 499-506
    • Erion, D.M.1    Ignatova, I.D.2    Yonemitsu, S.3    Nagai, Y.4    Chatterjee, P.5
  • 22
    • 65549171104 scopus 로고    scopus 로고
    • Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles
    • Yellaturu CR, Deng X, Cagen LM, Wilcox HG, Mansbach CM, 2nd, et al (2009) Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles. The Journal of biological chemistry 284: 7518-7532.
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 7518-7532
    • Yellaturu, C.R.1    Deng, X.2    Cagen, L.M.3    Wilcox, H.G.4    Mansbach 2nd, C.M.5
  • 23
    • 0026611169 scopus 로고
    • [Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis
    • Tal M, Wu YJ, Leiser M, Surana M, Lodish H, et al. (1992) [Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis. Proc Natl Acad Sci U S A 89: 5744-5748.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 5744-5748
    • Tal, M.1    Wu, Y.J.2    Leiser, M.3    Surana, M.4    Lodish, H.5
  • 24
    • 33847404482 scopus 로고    scopus 로고
    • Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease
    • Samuel VT, Liu ZX, Wang A, Beddow SA, Geisler JG, et al. (2007) Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. J Clin Invest 117: 739-745.
    • (2007) J Clin Invest , vol.117 , pp. 739-745
    • Samuel, V.T.1    Liu, Z.X.2    Wang, A.3    Beddow, S.A.4    Geisler, J.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.