Selective p38α MAP kinase/MAPK14 inhibition in enzymatically modified LDL-stimulated human monocytes: Implications for atherosclerosis

FASEB Journal

Volumn 31, Issue 2, 2017, Pages 674-686

  Cheng, Fei ^a,b   Twardowski, Laura ^a   Fehr, Sarah ^b   Aner, Christoph ^b   Schaeffeler, Elke ^b   Joos, Thomas ^b   Knorpp, Thomas ^b   Dorweiler, Bernhard ^c   Laufer, Stefan ^b   Schwab, Matthias ^b,d   Torzewski, Michael ^a,b  

^a ROBERT BOSCH HOSPITAL   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Cardiovascular research; IL 8; MIP 1b CCL4; Modified lipoproteins; Scavenger receptor CD36

Indexed keywords

ABC TRANSPORTER A1; CD36 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 16; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 23; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; LOW DENSITY LIPOPROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MONOCYTE CHEMOTACTIC PROTEIN 1; SKEPINONE L; UNCLASSIFIED DRUG; CASPASE 3; CASPASE 7; DIBENZO[A,D]CYCLOHEPTENE DERIVATIVE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SKEPINONE-L;

ADULT; AGED; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; FOAM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPOPROTEIN METABOLISM; MACROPHAGE; MALE; MOLECULAR PATHOLOGY; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MAPK SIGNALING; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ATHEROSCLEROSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CHOLESTEROL, LDL; DIBENZOCYCLOHEPTENES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 14; MONOCYTES;

EID: 85011273456     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201600669R     Document Type: Article

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