-
2
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P, (2002) Inflammation in atherosclerosis. Nature 420: 868-874.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
3
-
-
67650720510
-
Immune and inflammatory mechanisms of atherosclerosis (*)
-
Galkina E, Ley K, (2009) Immune and inflammatory mechanisms of atherosclerosis (*). Annu Rev Immunol 27: 165-197.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 165-197
-
-
Galkina, E.1
Ley, K.2
-
4
-
-
33745571976
-
The immune response in atherosclerosis: a double-edged sword
-
Hansson GK, Libby P, (2006) The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 6: 508-519.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 508-519
-
-
Hansson, G.K.1
Libby, P.2
-
5
-
-
66349092815
-
Mechanisms and consequences of macrophage apoptosis in atherosclerosis
-
Seimon T, Tabas I, (2009) Mechanisms and consequences of macrophage apoptosis in atherosclerosis. J Lipid Res 50 (Suppl): S382-387.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
, pp. 382-387
-
-
Seimon, T.1
Tabas, I.2
-
6
-
-
0346727295
-
Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice
-
Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, et al. (2003) Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice. J Clin Invest 112: 1176-1185.
-
(2003)
J Clin Invest
, vol.112
, pp. 1176-1185
-
-
Kanters, E.1
Pasparakis, M.2
Gijbels, M.J.3
Vergouwe, M.N.4
Partouns-Hendriks, I.5
-
7
-
-
54849412805
-
Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis
-
Gareus R, Kotsaki E, Xanthoulea S, van der Made I, Gijbels MJ, et al. (2008) Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis. Cell Metab 8: 372-383.
-
(2008)
Cell Metab
, vol.8
, pp. 372-383
-
-
Gareus, R.1
Kotsaki, E.2
Xanthoulea, S.3
van der Made, I.4
Gijbels, M.J.5
-
8
-
-
65249123061
-
Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice
-
Seimon TA, Wang Y, Han S, Senokuchi T, Schrijvers DM, et al. (2009) Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice. J Clin Invest 119: 886-898.
-
(2009)
J Clin Invest
, vol.119
, pp. 886-898
-
-
Seimon, T.A.1
Wang, Y.2
Han, S.3
Senokuchi, T.4
Schrijvers, D.M.5
-
9
-
-
33745530860
-
The many paths to p38 mitogen-activated protein kinase activation in the immune system
-
Ashwell JD, (2006) The many paths to p38 mitogen-activated protein kinase activation in the immune system. Nat Rev Immunol 6: 532-540.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 532-540
-
-
Ashwell, J.D.1
-
10
-
-
0142026209
-
P38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases
-
Kumar S, Boehm J, Lee JC, (2003) p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2: 717-726.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 717-726
-
-
Kumar, S.1
Boehm, J.2
Lee, J.C.3
-
11
-
-
27944461325
-
Generation and characterization of p38beta (MAPK11) gene-targeted mice
-
Beardmore VA, Hinton HJ, Eftychi C, Apostolaki M, Armaka M, et al. (2005) Generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol Cell Biol 25: 10454-10464.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10454-10464
-
-
Beardmore, V.A.1
Hinton, H.J.2
Eftychi, C.3
Apostolaki, M.4
Armaka, M.5
-
12
-
-
0036339127
-
Activation of the p38 MAP kinase pathway is required for foam cell formation from macrophages exposed to oxidized LDL
-
Zhao M, Liu Y, Wang X, New L, Han J, et al. (2002) Activation of the p38 MAP kinase pathway is required for foam cell formation from macrophages exposed to oxidized LDL. Apmis 110: 458-468.
-
(2002)
Apmis
, vol.110
, pp. 458-468
-
-
Zhao, M.1
Liu, Y.2
Wang, X.3
New, L.4
Han, J.5
-
13
-
-
0036164803
-
OxLDL upregulates CXCR2 expression in monocytes via scavenger receptors and activation of p38 mitogen-activated protein kinase
-
Lei ZB, Zhang Z, Jing Q, Qin YW, Pei G, et al. (2002) OxLDL upregulates CXCR2 expression in monocytes via scavenger receptors and activation of p38 mitogen-activated protein kinase. Cardiovasc Res 53: 524-532.
-
(2002)
Cardiovasc Res
, vol.53
, pp. 524-532
-
-
Lei, Z.B.1
Zhang, Z.2
Jing, Q.3
Qin, Y.W.4
Pei, G.5
-
14
-
-
0035984947
-
Pharmacologically activated migration of aortic endothelial cells is mediated through p38 SAPK
-
Denes L, Jednakovits A, Hargitai J, Penzes Z, Balla A, et al. (2002) Pharmacologically activated migration of aortic endothelial cells is mediated through p38 SAPK. Br J Pharmacol 136: 597-603.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 597-603
-
-
Denes, L.1
Jednakovits, A.2
Hargitai, J.3
Penzes, Z.4
Balla, A.5
-
15
-
-
20444385832
-
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells
-
McMullen ME, Bryant PW, Glembotski CC, Vincent PA, Pumiglia KM, (2005) Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. J Biol Chem 280: 20995-21003.
-
(2005)
J Biol Chem
, vol.280
, pp. 20995-21003
-
-
McMullen, M.E.1
Bryant, P.W.2
Glembotski, C.C.3
Vincent, P.A.4
Pumiglia, K.M.5
-
16
-
-
6344254520
-
P38 MAP kinase-dependent regulation of endothelial cell permeability
-
Borbiev T, Birukova A, Liu F, Nurmukhambetova S, Gerthoffer WT, et al. (2004) p38 MAP kinase-dependent regulation of endothelial cell permeability. Am J Physiol Lung Cell Mol Physiol 287: L911-918.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
, pp. 911-918
-
-
Borbiev, T.1
Birukova, A.2
Liu, F.3
Nurmukhambetova, S.4
Gerthoffer, W.T.5
-
17
-
-
0035839556
-
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells
-
Gratton JP, Morales-Ruiz M, Kureishi Y, Fulton D, Walsh K, et al. (2001) Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells. J Biol Chem 276: 30359-30365.
-
(2001)
J Biol Chem
, vol.276
, pp. 30359-30365
-
-
Gratton, J.P.1
Morales-Ruiz, M.2
Kureishi, Y.3
Fulton, D.4
Walsh, K.5
-
18
-
-
1942521356
-
Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells
-
Viemann D, Goebeler M, Schmid S, Klimmek K, Sorg C, et al. (2004) Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells. Blood 103: 3365-3373.
-
(2004)
Blood
, vol.103
, pp. 3365-3373
-
-
Viemann, D.1
Goebeler, M.2
Schmid, S.3
Klimmek, K.4
Sorg, C.5
-
19
-
-
33750086376
-
Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages
-
Smith SJ, Fenwick PS, Nicholson AG, Kirschenbaum F, Finney-Hayward TK, et al. (2006) Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages. Br J Pharmacol 149: 393-404.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 393-404
-
-
Smith, S.J.1
Fenwick, P.S.2
Nicholson, A.G.3
Kirschenbaum, F.4
Finney-Hayward, T.K.5
-
20
-
-
50049122380
-
The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression
-
Kim C, Sano Y, Todorova K, Carlson BA, Arpa L, et al. (2008) The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression. Nat Immunol 9: 1019-1027.
-
(2008)
Nat Immunol
, vol.9
, pp. 1019-1027
-
-
Kim, C.1
Sano, Y.2
Todorova, K.3
Carlson, B.A.4
Arpa, L.5
-
21
-
-
33744527608
-
Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase
-
Nolden L, Edenhofer F, Haupt S, Koch P, Wunderlich FT, et al. (2006) Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase. Nat Methods 3: 461-467.
-
(2006)
Nat Methods
, vol.3
, pp. 461-467
-
-
Nolden, L.1
Edenhofer, F.2
Haupt, S.3
Koch, P.4
Wunderlich, F.T.5
-
22
-
-
27744496768
-
The biology of p38 kinase: a central role in inflammation
-
Schieven GL, (2005) The biology of p38 kinase: a central role in inflammation. Curr Top Med Chem 5: 921-928.
-
(2005)
Curr Top Med Chem
, vol.5
, pp. 921-928
-
-
Schieven, G.L.1
-
23
-
-
0036687898
-
Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements
-
Forde A, Constien R, Grone HJ, Hammerling G, Arnold B, (2002) Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements. Genesis 33: 191-197.
-
(2002)
Genesis
, vol.33
, pp. 191-197
-
-
Forde, A.1
Constien, R.2
Grone, H.J.3
Hammerling, G.4
Arnold, B.5
-
24
-
-
33846828631
-
Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate
-
Kiermayer C, Conrad M, Schneider M, Schmidt J, Brielmeier M, (2007) Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate. Genesis 45: 11-16.
-
(2007)
Genesis
, vol.45
, pp. 11-16
-
-
Kiermayer, C.1
Conrad, M.2
Schneider, M.3
Schmidt, J.4
Brielmeier, M.5
-
25
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
Clausen BE, Burkhardt C, Reith W, Renkawitz R, Forster I, (1999) Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res 8: 265-277.
-
(1999)
Transgenic Res
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Forster, I.5
-
26
-
-
7244243748
-
Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor
-
Westra J, Doornbos-van der Meer B, de Boer P, van Leeuwen MA, van Rijswijk MH, et al. (2004) Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor. Arthritis Res Ther 6: R384-392.
-
(2004)
Arthritis Res Ther
, vol.6
, pp. 384-392
-
-
Westra, J.1
van der Meer, B.D.2
de Boer, P.3
van Leeuwen, M.A.4
van Rijswijk, M.H.5
-
27
-
-
34547154349
-
P38 MAP-kinases pathway regulation, function and role in human diseases
-
Cuenda A, Rousseau S, (2007) p38 MAP-kinases pathway regulation, function and role in human diseases. Biochim Biophys Acta 1773: 1358-1375.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1358-1375
-
-
Cuenda, A.1
Rousseau, S.2
-
28
-
-
36348954401
-
Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice
-
Jagavelu K, Tietge UJ, Gaestel M, Drexler H, Schieffer B, et al. (2007) Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice. Circ Res 101: 1104-1112.
-
(2007)
Circ Res
, vol.101
, pp. 1104-1112
-
-
Jagavelu, K.1
Tietge, U.J.2
Gaestel, M.3
Drexler, H.4
Schieffer, B.5
-
29
-
-
53249111250
-
P38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure
-
Heinrichsdorff J, Luedde T, Perdiguero E, Nebreda AR, Pasparakis M, (2008) p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure. EMBO Rep 9: 1048-1054.
-
(2008)
EMBO Rep
, vol.9
, pp. 1048-1054
-
-
Heinrichsdorff, J.1
Luedde, T.2
Perdiguero, E.3
Nebreda, A.R.4
Pasparakis, M.5
-
30
-
-
0026592806
-
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
-
Zhang SH, Reddick RL, Piedrahita JA, Maeda N, (1992) Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258: 468-471.
-
(1992)
Science
, vol.258
, pp. 468-471
-
-
Zhang, S.H.1
Reddick, R.L.2
Piedrahita, J.A.3
Maeda, N.4
-
31
-
-
9444277846
-
Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis
-
Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, et al. (2004) Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. Science 306: 1558-1561.
-
(2004)
Science
, vol.306
, pp. 1558-1561
-
-
Ricci, R.1
Sumara, G.2
Sumara, I.3
Rozenberg, I.4
Kurrer, M.5
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