Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 5, 2017, Pages E751-E760

  Hardbower, Dana M ^a   Asim, Mohammad ^a   Luis, Paula B ^b   Singh, Kshipra ^a   Barry, Daniel P ^a   Yang, Chunying ^c,d   Steeves, Meredith A ^d   Cleveland, John L ^c,d   Schneider, Claus ^b   Piazuelo, M Blanca ^a   Gobert, Alain P ^a   Wilson, Keith T ^a,b,e  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Helicobacter pylori; Histone modifications; Macrophage polarization; Ornithine decarboxylase; Polyamines

Indexed keywords

ARGINASE 1; CCAAT ENHANCER BINDING PROTEIN DELTA; CHITINASE 3 LIKE PROTEIN 1; CRYOPYRIN; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE 3 LYSINE 4; HISTONE H3; HISTONE H3K9; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLAMMASOME; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; ORNITHINE DECARBOXYLASE; PUTRESCINE; RANTES; RESISTIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE; HISTONE; NLRP3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BACTERICIDAL ACTIVITY; BONE MARROW CELL; CHROMATIN STRUCTURE; CITROBACTER RODENTIUM; COLITIS; COLON MUCOSA; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; ENTEROBACTERIACEAE INFECTION; EPITHELIUM CELL; EX VIVO STUDY; FEMALE; GASTRITIS; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HELICOBACTER INFECTION; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREGULATION; IN VIVO STUDY; MACROPHAGE ACTIVATION; MALE; MOUSE; MUCOSA INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; STOMACH EPITHELIUM; STOMACH MUCOSA; STOMACH TISSUE; UPREGULATION; ANIMAL; CELL LINE; COLON; GENETICS; HELICOBACTER PYLORI; IMMUNOLOGY; MACROPHAGE; METABOLISM; PATHOLOGY;

ANIMALS; CELL LINE; CITROBACTER RODENTIUM; COLITIS; COLON; CYTOKINES; ENTEROBACTERIACEAE INFECTIONS; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HISTONES; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; ORNITHINE DECARBOXYLASE; PUTRESCINE;

EID: 85011268659     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1614958114     Document Type: Article

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