Difluoromethylornithine is a novel inhibitor of helicobacter pylori growth, cagA translocation, and interleukin-8 induction

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Barry, Daniel P ^a,c   Asim, Mohammad ^a,c   Leiman, David A ^a   de Sablet, Thibaut ^a,c   Singh, Kshipra ^a,c   Casero, Robert A ^d   Chaturvedi, Rupesh ^a,c   Wilson, Keith T ^a,b,c  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CAGA PROTEIN; EFLORNITHINE; INTERLEUKIN 8; MESSENGER RNA; ORNITHINE DECARBOXYLASE; POLYAMINE; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CAGA PROTEIN, HELICOBACTER PYLORI; ENZYME INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL VIRULENCE; CITROBACTER RODENTIUM; CONTROLLED STUDY; DRUG EFFICACY; DRUG EXPOSURE; ENZYME INHIBITION; EPITHELIUM CELL; ESCHERICHIA COLI; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; STOMACH EPITHELIUM; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; EVALUATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; STOMACH MUCOSA; TRANSCRIPTION INITIATION;

BACTERIA (MICROORGANISMS); CITROBACTER RODENTIUM; ESCHERICHIA COLI; HELICOBACTER PYLORI; MUS; NEGIBACTERIA;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELLS, CULTURED; EFLORNITHINE; ENZYME INHIBITORS; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTERLEUKIN-8; MALE; MICE; MICE, INBRED C57BL; PROTEIN TRANSPORT; TRANSCRIPTIONAL ACTIVATION;

EID: 79952239514     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017510     Document Type: Article

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