Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection

Amino Acids

Volumn 48, Issue 10, 2016, Pages 2375-2388

  Hardbower, Dana M ^a   Asim, Mohammad ^a   Murray Stewart, Tracy ^b   Casero, Robert A ^b   Verriere, Thomas ^a   Lewis, Nuruddeen D ^a   Chaturvedi, Rupesh ^a,c   Piazuelo, M Blanca ^a   Wilson, Keith T ^a,d,e  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c JAWAHARLAL NEHRU UNIVERSITY   (India)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Helicobacter pylori; Immune evasion; Macrophage activation; Polyamines

Indexed keywords

ADENOSYLMETHIONINE DECARBOXYLASE; ADENOSYLMETHIONINE DECARBOXYLASE 1; ARGINASE; ARGINASE 2; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 17; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; ORNITHINE DECARBOXYLASE; RANTES; SPERMIDINE; SPERMINE DERIVATIVE; SPERMINE OXIDASE; UNCLASSIFIED DRUG; ARG2 PROTEIN, MOUSE; NOS2 PROTEIN, MOUSE; POLYAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARG2 GENE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL LOAD; CONTROLLED STUDY; GASTRIC MACROPHAGE; GASTRITIS; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; HELICOBACTER INFECTION; IMMUNOPATHOGENESIS; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; POLYAMINE METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; TH17 CELL; UPREGULATION; WILD TYPE MOUSE; ANIMAL; GENETICS; HELICOBACTER PYLORI; IMMUNE EVASION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PATHOLOGY; STOMACH;

ANIMALS; ARGINASE; BIOGENIC POLYAMINES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; IMMUNE EVASION; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE TYPE II; STOMACH; TH1 CELLS; TH17 CELLS;

EID: 84963705390     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-016-2231-2     Document Type: Article

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