MTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis

Nature Communications

Volumn 8, Issue , 2017, Pages

  Hallowell, R W ^a   Collins, S L ^b   Craig, J M ^c   Zhang, Y ^d   Oh, M ^b   Illei, P B ^b   Chan Li, Y ^b   Vigeland, C L ^b   Mitzner, W ^c   Scott, A L ^c   Powell, J D ^b   Horton, M R ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d TONGJI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACOX1 PROTEIN; ADAPTOR PROTEIN; ARGINASE 1; BETA ADRENERGIC RECEPTOR; CD206 ANTIGEN; FIZZ1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 12P35; INTERLEUKIN 6; KI 67 ANTIGEN; LYMPHOCYTE ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MEMBRANE PROTEIN; NORADRENALIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROGRAMMED DEATH 1 LIGAND 1; PROTEIN KINASE B; RANTES; RICTOR PROTEIN; S6 KINASE; STAT6 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR MASH1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; YM1 PROTEIN; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; RICTOR PROTEIN, MOUSE;

BODY TEMPERATURE; CELLS AND CELL COMPONENTS; FLATWORM; IMMUNE RESPONSE; INFECTIVITY; METABOLISM; RODENT; SENSORY SYSTEM;

ADAPTIVE BEHAVIOR; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CORE TEMPERATURE; FEMALE; GENE DELETION; HOOKWORM INFECTION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MACROPHAGE ACTIVATION; MALE; METABOLISM; MOUSE; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PARASITE CLEARANCE; PARASITE LOAD; THERMOGENESIS; THERMOREGULATION; ANIMAL; ANIMAL PARASITOSIS; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; GENE KNOCKOUT; GENETICS; HUMAN; IMMUNOLOGY; MACROPHAGE; NIPPOSTRONGYLUS; PARASITOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; STRONGYLE INFECTION;

MUS; VERMES;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCKOUT TECHNIQUES; HELMINTHIASIS, ANIMAL; HUMANS; IMMUNITY, INNATE; MACROPHAGES; MALE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 2; MICE; MICE, INBRED C57BL; NIPPOSTRONGYLUS; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR PROTEIN; SIGNAL TRANSDUCTION; STRONGYLIDA INFECTIONS; THERMOGENESIS;

EID: 85010977474     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14208     Document Type: Article

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