메뉴 건너뛰기




Volumn 80, Issue 10, 2012, Pages 3481-3489

Type 2 innate immunity in helminth infection is induced redundantly and acts autonomously following cd11c+ cell depletion

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; CELL PROTEIN; GLYCOPROTEIN P 15095; RELM ALPHA PROTEIN; SOLUBLE EXCRETORY SECRETORY PRODUCT; UNCLASSIFIED DRUG; YM 1 PROTEIN;

EID: 84867605412     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00436-12     Document Type: Article
Times cited : (48)

References (70)
  • 1
    • 0030050801 scopus 로고    scopus 로고
    • Antigen presenting cells from mice harboring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production
    • Allen JE, Lawrence RA, Maizels RM. 1996. Antigen presenting cells from mice harboring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. Int. Immunol. 8:143-151.
    • (1996) Int. Immunol. , vol.8 , pp. 143-151
    • Allen, J.E.1    Lawrence, R.A.2    Maizels, R.M.3
  • 2
    • 79957609041 scopus 로고    scopus 로고
    • Diversity and dialogue in immunity to helminths
    • Allen JE, Maizels RM. 2011. Diversity and dialogue in immunity to helminths. Nat. Rev. Immunol. 11:375-388.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 375-388
    • Allen, J.E.1    Maizels, R.M.2
  • 4
    • 33746806604 scopus 로고    scopus 로고
    • Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites
    • Anthony RM, et al. 2006. Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat. Med. 12:955-960.
    • (2006) Nat. Med. , vol.12 , pp. 955-960
    • Anthony, R.M.1
  • 5
    • 9244249137 scopus 로고    scopus 로고
    • Selective maturation of dendritic cells by Nippostrongylus brasiliensis secreted proteins drives T helper type 2 immune responses
    • Balic A, Harcus Y, Holland MJ, Maizels RM. 2004. Selective maturation of dendritic cells by Nippostrongylus brasiliensis secreted proteins drives T helper type 2 immune responses. Eur. J. Immunol. 34:3047-3059.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 3047-3059
    • Balic, A.1    Harcus, Y.2    Holland, M.J.3    Maizels, R.M.4
  • 6
    • 33748991140 scopus 로고    scopus 로고
    • IL- 4R signaling is required to induce IL-10 for the establishment of Th2 dominance
    • Balic A, Harcus YM, Taylor MD, Brombacher F, Maizels RM. 2006. IL-4R signaling is required to induce IL-10 for the establishment of Th2 dominance. Int. Immunol. 18:1421-1431.
    • (2006) Int. Immunol. , vol.18 , pp. 1421-1431
    • Balic, A.1    Harcus, Y.M.2    Taylor, M.D.3    Brombacher, F.4    Maizels, R.M.5
  • 7
    • 0025759204 scopus 로고
    • Heligmosomoides polygyrus or Nematospiroides dubius? Parasitol
    • Behnke JM, Keymer AE, Lewis JW. 1991. Heligmosomoides polygyrus or Nematospiroides dubius? Parasitol. Today 7:177-179.
    • (1991) Today , vol.7 , pp. 177-179
    • Behnke, J.M.1    Keymer, A.E.2    Lewis, J.W.3
  • 8
    • 0842343445 scopus 로고    scopus 로고
    • Dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminthspecific Th2 responses
    • Cervi L, MacDonald AS, Kane C, Dzierszinski F, Pearce EJ. 2004. Dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminthspecific Th2 responses. J. Immunol. 172:2016 -2020.
    • (2004) J. Immunol. , vol.172 , pp. 2016-2020
    • Cervi, L.1    MacDonald, A.S.2    Kane, C.3    Dzierszinski, F.4    Pearce, E.J.5
  • 9
    • 29644442357 scopus 로고    scopus 로고
    • Helminth-primed dendritic cells alter the host response to enteric bacterial infection
    • Chen C-C, Louie S, McCormick BA, Walker WA, Shi HN. 2006. Helminth-primed dendritic cells alter the host response to enteric bacterial infection. J. Immunol. 176:472- 483.
    • (2006) J. Immunol. , vol.176 , pp. 472-483
    • Chen, C.-C.1    Louie, S.2    McCormick, B.A.3    Walker, W.A.4    Shi, H.N.5
  • 10
    • 45549087159 scopus 로고    scopus 로고
    • Basophils enhance immunological memory responses
    • Denzel A, et al. 2008. Basophils enhance immunological memory responses. Nat. Immunol. 9:733-742.
    • (2008) Nat. Immunol. , vol.9 , pp. 733-742
    • Denzel, A.1
  • 11
    • 68149156007 scopus 로고    scopus 로고
    • Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses
    • Everts B, et al. 2009. Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J. Exp. Med. 206:1673-1680.
    • (2009) J. Exp. Med. , vol.206 , pp. 1673-1680
    • Everts, B.1
  • 12
    • 77953299188 scopus 로고    scopus 로고
    • Sensing of helminth infections by dendritic cells via pattern recognition receptors and beyond: consequences for T helper 2 and regulatory T cell polarization
    • Everts B, Smits HH, Hokke CH, Yazdankbakhsh M. 2010. Sensing of helminth infections by dendritic cells via pattern recognition receptors and beyond: consequences for T helper 2 and regulatory T cell polarization. Eur. J. Immunol. 40:1525-1537.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1525-1537
    • Everts, B.1    Smits, H.H.2    Hokke, C.H.3    Yazdankbakhsh, M.4
  • 14
    • 0038739290 scopus 로고    scopus 로고
    • The immune response to parasitic helminths: insights from murine models
    • Gause WC, Urban JF, Jr., Stadecker MJ. 2003. The immune response to parasitic helminths: insights from murine models. Trends Immunol. 24: 269-277.
    • (2003) Trends Immunol , vol.24 , pp. 269-277
    • Gause, W.C.1    Urban Jr., J.F.2    Stadecker, M.J.3
  • 15
    • 77957745031 scopus 로고    scopus 로고
    • Inflammatory dendritic cells-not basophils- are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
    • Hammad H, et al. 2010. Inflammatory dendritic cells-not basophils- are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J. Exp. Med. 207:2097-2111.
    • (2010) J. Exp. Med. , vol.207 , pp. 2097-2111
    • Hammad, H.1
  • 16
    • 73949086150 scopus 로고    scopus 로고
    • Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection
    • Herbert DR, et al. 2009. Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection. J. Exp. Med. 206:2947- 2957.
    • (2009) J. Exp. Med. , vol.206 , pp. 2947-2957
    • Herbert, D.R.1
  • 17
    • 67650355471 scopus 로고    scopus 로고
    • Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity
    • Hewitson JP, Grainger JR, Maizels RM. 2009. Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. Mol. Biochem. Parasitol. 167:1-11.
    • (2009) Mol. Biochem. Parasitol. , vol.167 , pp. 1-11
    • Hewitson, J.P.1    Grainger, J.R.2    Maizels, R.M.3
  • 18
    • 80051671154 scopus 로고    scopus 로고
    • Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins
    • Hewitson JP, et al. 2011. Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins. J. Proteomics 74: 1573-1594.
    • (2011) J. Proteomics , vol.74 , pp. 1573-1594
    • Hewitson, J.P.1
  • 19
    • 73349107768 scopus 로고    scopus 로고
    • Homeostasis of dendritic cells in lymphoid organs is controlled by regulation of their precursors via a feedback loop
    • Hochweller K, et al. 2009. Homeostasis of dendritic cells in lymphoid organs is controlled by regulation of their precursors via a feedback loop. Blood 114:4411- 4421.
    • (2009) Blood , vol.114 , pp. 4411-4421
    • Hochweller, K.1
  • 20
    • 58149229634 scopus 로고    scopus 로고
    • A novel CD11c DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells
    • Hochweller K, Striegler J, Hammerling GJ, Garbi N. 2008. A novel CD11c.DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells. Eur. J. Immunol. 38:2776 -2783.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2776-2783
    • Hochweller, K.1    Striegler, J.2    Hammerling, G.J.3    Garbi, N.4
  • 21
    • 0033922732 scopus 로고    scopus 로고
    • Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses
    • Holland MJ, Harcus YM, Riches PL, Maizels RM. 2000. Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. Eur. J. Immunol. 30:1977-1987.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1977-1987
    • Holland, M.J.1    Harcus, Y.M.2    Riches, P.L.3    Maizels, R.M.4
  • 23
    • 79952103794 scopus 로고    scopus 로고
    • Emerging roles of basophils in protective immunity against parasites
    • Karasuyama H, Wada T, Yoshikawa S, Obata K. 2011. Emerging roles of basophils in protective immunity against parasites. Trends Immunol. 32: 125-130.
    • (2011) Trends. Immunol , vol.32 , pp. 125-130
    • Karasuyama, H.1    Wada, T.2    Yoshikawa, S.3    Obata, K.4
  • 24
    • 77249158040 scopus 로고    scopus 로고
    • Basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3
    • Kim S, et al. 2010. Basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3. J. Immunol. 184:1143-1147.
    • (2010) J. Immunol. , vol.184 , pp. 1143-1147
    • Kim, S.1
  • 25
    • 78149238566 scopus 로고    scopus 로고
    • Natural helper cells: a new player in the innate immune response against helminth infection
    • Koyasu S, Moro K, Tanabe M, Takeuchi T. 2010. Natural helper cells: a new player in the innate immune response against helminth infection. Adv. Immunol. 108:21- 44.
    • (2010) Adv. Immunol. , vol.108 , pp. 21-44
    • Koyasu, S.1    Moro, K.2    Tanabe, M.3    Takeuchi, T.4
  • 27
    • 35748964164 scopus 로고    scopus 로고
    • + T cells to be sustained during chronic infection
    • + T cells to be sustained during chronic infection. J. Immunol. 179:3926 -3936.
    • (2007) J. Immunol. , vol.179 , pp. 3926-3936
    • Loke, P.1
  • 28
    • 38749095928 scopus 로고    scopus 로고
    • Alarming dendritic cells for Th2 induction
    • MacDonald AS, Maizels RM. 2008. Alarming dendritic cells for Th2 induction. J. Exp. Med. 205:13-17.
    • (2008) J. Exp. Med. , vol.205 , pp. 13-17
    • MacDonald, A.S.1    Maizels, R.M.2
  • 31
    • 84865551579 scopus 로고    scopus 로고
    • Immune modulation and modulators in Heligmosomoides polygyrus infection
    • Maizels RM, et al. 2012. Immune modulation and modulators in Heligmosomoides polygyrus infection. Exp. Parasitol. 132:76-89.
    • (2012) Exp. Parasitol. , vol.132 , pp. 76-89
    • Maizels, R.M.1
  • 32
    • 0033577811 scopus 로고    scopus 로고
    • Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses
    • McKenzie GJ, Fallon PG, Emson CL, Grencis RK, McKenzie AN. 1999. Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J. Exp. Med. 189: 1565-1572.
    • (1999) J. Exp. Med. , vol.189 , pp. 1565-1572
    • McKenzie, G.J.1    Fallon, P.G.2    Emson, C.L.3    Grencis, R.K.4    McKenzie, A.N.5
  • 33
    • 4344647601 scopus 로고    scopus 로고
    • Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite
    • Min B, et al. 2004. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J. Exp. Med. 200:507-517.
    • (2004) J. Exp. Med. , vol.200 , pp. 507-517
    • Min, B.1
  • 34
    • 34547645582 scopus 로고    scopus 로고
    • Resistin-like molecule-β is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung
    • Mishra A, et al. 2007. Resistin-like molecule-β is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 293:L305-L313.
    • (2007) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.293
    • Mishra, A.1
  • 35
    • 75749122181 scopus 로고    scopus 로고
    • + lymphoid cells
    • + lymphoid cells. Nature 463:540 -544.
    • (2010) Nature , vol.463 , pp. 540-544
    • Moro, K.1
  • 36
    • 11144286421 scopus 로고    scopus 로고
    • Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells
    • Nair MG, et al. 2005. Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells. Infect. Immun. 73:385-394.
    • (2005) Infect. Immun. , vol.73 , pp. 385-394
    • Nair, M.G.1
  • 37
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill DR, et al. 2010. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464:1367-1370.
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1
  • 38
    • 79955030122 scopus 로고    scopus 로고
    • Impaired basophil induction leads to age-dependent innate defect in type 2 immunity during helminth infection in mice
    • Nel HJ, et al. 2011. Impaired basophil induction leads to age-dependent innate defect in type 2 immunity during helminth infection in mice. J. Immunol. 186:4631- 4639.
    • (2011) J. Immunol. , vol.186 , pp. 4631-4639
    • Nel, H.J.1
  • 39
    • 77957020655 scopus 로고    scopus 로고
    • Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths
    • Ohnmacht C, et al. 2010. Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths. Immunity 33:364 -374.
    • (2010) Immunity , vol.33 , pp. 364-374
    • Ohnmacht, C.1
  • 40
    • 63849092743 scopus 로고    scopus 로고
    • Basophil effector function and homeostasis during helminth infection
    • Ohnmacht C, Voehringer D. 2009. Basophil effector function and homeostasis during helminth infection. Blood 113:2816 -2825.
    • (2009) Blood , vol.113 , pp. 2816-2825
    • Ohnmacht, C.1    Voehringer, D.2
  • 41
    • 73949111782 scopus 로고    scopus 로고
    • Basophils protect against reinfection with hookworms independently of mast cells and memory Th2 cells
    • Ohnmacht C, Voehringer D. 2010. Basophils protect against reinfection with hookworms independently of mast cells and memory Th2 cells. J. Immunol. 184:344 -350.
    • (2010) J. Immunol. , vol.184 , pp. 344-350
    • Ohnmacht, C.1    Voehringer, D.2
  • 42
    • 77950261975 scopus 로고    scopus 로고
    • How are TH2-type immune responses initiated and amplified? Nat
    • Paul WE, Zhu J. 2010. How are TH2-type immune responses initiated and amplified? Nat. Rev. Immunol. 10:225-235.
    • (2010) Rev. Immunol. , vol.10 , pp. 225-235
    • Paul, W.E.1    Zhu, J.2
  • 43
    • 4844229519 scopus 로고    scopus 로고
    • Th2 response polarization during infection with the helminth parasite Schistosoma mansoni
    • Pearce EJ, et al. 2004. Th2 response polarization during infection with the helminth parasite Schistosoma mansoni. Immunol. Rev. 201:117-126.
    • (2004) Immunol. Rev. , vol.201 , pp. 117-126
    • Pearce, E.J.1
  • 44
    • 67649229687 scopus 로고    scopus 로고
    • + T cell interactions promote TH2 cytokine-dependent immunity
    • + T cell interactions promote TH2 cytokine-dependent immunity. Nat. Immunol. 10:697-705.
    • (2009) Nat. Immunol. , vol.10 , pp. 697-705
    • Perrigoue, J.G.1
  • 45
    • 77957731193 scopus 로고    scopus 로고
    • CD11c depletion severely disrupts Th2 induction and development in vivo
    • Phythian-Adams AT, et al. 2010. CD11c depletion severely disrupts Th2 induction and development in vivo. J. Exp. Med. 207:2089 -2096.
    • (2010) J. Exp. Med. , vol.207 , pp. 2089-2096
    • Phythian-Adams, A.T.1
  • 46
    • 77954926597 scopus 로고    scopus 로고
    • Systemically dispersed innate IL-13-expressing cells in type 2 immunity
    • Price AE, et al. 2010. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc. Natl. Acad. Sci. U. S. A. 107:11489 -11494.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 11489-11494
    • Price, A.E.1
  • 47
    • 65549095053 scopus 로고    scopus 로고
    • MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages
    • Prieto-Lafuente L, Gregory WF, Allen JE, Maizels RM. 2009. MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages. J. Leuk. Biol. 85:844- 854.
    • (2009) J. Leuk. Biol. , vol.85 , pp. 844-854
    • Prieto-Lafuente, L.1    Gregory, W.F.2    Allen, J.E.3    Maizels, R.M.4
  • 48
    • 0019472131 scopus 로고
    • Eosinophilia in athymic nude (rnu/rnu) rats-thymus-independent eosinophilia?
    • Pritchard DI, Eady RP. 1981. Eosinophilia in athymic nude (rnu/rnu) rats-thymus-independent eosinophilia? Immunology 43:409-416.
    • (1981) Immunology , vol.43 , pp. 409-416
    • Pritchard, D.I.1    Eady, R.P.2
  • 49
    • 42949155819 scopus 로고    scopus 로고
    • Functional analysis of effector and regulatory T cells in a parasitic nematode infection
    • Rausch S, et al. 2008. Functional analysis of effector and regulatory T cells in a parasitic nematode infection. Infect. Immun. 76:1908 -1919.
    • (2008) Infect. Immun. , vol.76 , pp. 1908-1919
    • Rausch, S.1
  • 50
    • 33748087483 scopus 로고    scopus 로고
    • Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages
    • Reece JJ, Siracusa MC, Scott AL. 2006. Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages. Infect. Immun. 74:4970-4981.
    • (2006) Infect. Immun. , vol.74 , pp. 4970-4981
    • Reece, J.J.1    Siracusa, M.C.2    Scott, A.L.3
  • 51
    • 77951817294 scopus 로고    scopus 로고
    • IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses
    • Saenz SA, et al. 2010. IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses. Nature 464:1362-1366.
    • (2010) Nature , vol.464 , pp. 1362-1366
    • Saenz, S.A.1
  • 52
    • 4043146413 scopus 로고    scopus 로고
    • Chronic intestinal nematode infection induces Stat6-independent interleukin-5 production and causes eosinophilic inflammatory responses in mice
    • Sakamoto Y, et al. 2004. Chronic intestinal nematode infection induces Stat6-independent interleukin-5 production and causes eosinophilic inflammatory responses in mice. Immunology 112:615- 623.
    • (2004) Immunology , vol.112 , pp. 615-623
    • Sakamoto, Y.1
  • 53
    • 79955746123 scopus 로고    scopus 로고
    • The control of adaptive immune responses by the innate immune system
    • Schenten D, Medzhitov R. 2011. The control of adaptive immune responses by the innate immune system. Adv. Immunol. 109:87-124.
    • (2011) Adv. Immunol. , vol.109 , pp. 87-124
    • Schenten, D.1    Medzhitov, R.2
  • 54
    • 0025923922 scopus 로고
    • + bone marrow and splenic non-B, non-T cells are highly enriched in the capacity to produce IL-4 in response to immobilized IgE, IgG2a, or ionomycin
    • + bone marrow and splenic non-B, non-T cells are highly enriched in the capacity to produce IL-4 in response to immobilized IgE, IgG2a, or ionomycin. J. Immunol. 147:903-909.
    • (1991) J. Immunol. , vol.147 , pp. 903-909
    • Seder, R.A.1
  • 55
    • 34447547494 scopus 로고    scopus 로고
    • Impairment of dendritic cell function by excretory-secretory products: a potential mechanism for nematode-induced immunosuppression
    • Segura M, Su Z, Piccirillo C, Stevenson MM. 2007. Impairment of dendritic cell function by excretory-secretory products: a potential mechanism for nematode-induced immunosuppression. Eur. J. Immunol. 37: 1887-1904.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1887-1904
    • Segura, M.1    Su, Z.2    Piccirillo, C.3    Stevenson, M.M.4
  • 56
    • 79959567420 scopus 로고    scopus 로고
    • lo CD103- DC population
    • lo CD103- DC population. J. Immunol. 186:7098 -7109.
    • (2011) J. Immunol. , vol.186 , pp. 7098-7109
    • Smith, K.A.1
  • 57
    • 39449133957 scopus 로고    scopus 로고
    • A mechanism for the initiation of allergen-induced T helper type 2 responses
    • Sokol CL, Barton GM, Farr AG, Medzhitov R. 2008. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat. Immunol. 9:310 -318.
    • (2008) Nat. Immunol. , vol.9 , pp. 310-318
    • Sokol, C.L.1    Barton, G.M.2    Farr, A.G.3    Medzhitov, R.4
  • 58
    • 67649216604 scopus 로고    scopus 로고
    • Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
    • Sokol CL, et al. 2009. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat. Immunol. 10:713-720.
    • (2009) Nat. Immunol. , vol.10 , pp. 713-720
    • Sokol, C.L.1
  • 59
    • 68149163162 scopus 로고    scopus 로고
    • The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)
    • Steinfelder S, et al. 2009. The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J. Exp. Med. 206:1681-1690.
    • (2009) J. Exp. Med. , vol.206 , pp. 1681-1690
    • Steinfelder, S.1
  • 60
    • 79956158089 scopus 로고    scopus 로고
    • Genetic analysis of basophil function in vivo
    • Sullivan BM, et al. 2011. Genetic analysis of basophil function in vivo. Nat. Immunol. 12:527-535.
    • (2011) Nat. Immunol. , vol.12 , pp. 527-535
    • Sullivan, B.M.1
  • 61
    • 33749340690 scopus 로고    scopus 로고
    • Schistosoma mansoni infection in eosinophil lineage-ablated mice
    • Swartz JM, et al. 2006. Schistosoma mansoni infection in eosinophil lineage-ablated mice. Blood 108:2420 -2427.
    • (2006) Blood , vol.108 , pp. 2420-2427
    • Swartz, J.M.1
  • 62
    • 0027439153 scopus 로고
    • Mechanisms of eosinophilia in Toxocara canis infected mice: in vitro production of interleukin 5 by lung cells of both normal and congenitally athymic nude mice
    • Takamoto M, Sugane K. 1993. Mechanisms of eosinophilia in Toxocara canis infected mice: in vitro production of interleukin 5 by lung cells of both normal and congenitally athymic nude mice. Parasite Immunol. 15: 493-500.
    • (1993) Parasite Immunol , vol.15 , pp. 493-500
    • Takamoto, M.1    Sugane, K.2
  • 63
    • 77953812779 scopus 로고    scopus 로고
    • The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling
    • Tang H, et al. 2010. The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat. Immunol. 11:608-617.
    • (2010) Nat. Immunol. , vol.11 , pp. 608-617
    • Tang, H.1
  • 64
    • 78650635339 scopus 로고    scopus 로고
    • Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis
    • Torrero MN, Hubner MP, Larson D, Karasuyama H, Mitre E. 2010. Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis. J. Immunol. 185:7426 -7434.
    • (2010) J. Immunol. , vol.185 , pp. 7426-7434
    • Torrero, M.N.1    Hubner, M.P.2    Larson, D.3    Karasuyama, H.4    Mitre, E.5
  • 65
    • 79952741741 scopus 로고    scopus 로고
    • Basophils are the major producers of IL-4 during primary helminth infection
    • van Panhuys N, et al. 2011. Basophils are the major producers of IL-4 during primary helminth infection. J. Immunol. 186:2719 -2728.
    • (2011) J. Immunol. , vol.186 , pp. 2719-2728
    • van Panhuys, N.1
  • 66
    • 17144367365 scopus 로고    scopus 로고
    • + dendritic cells during allergen challenge abrogates the characteristic features of asthma
    • + dendritic cells during allergen challenge abrogates the characteristic features of asthma. J. Exp. Med. 201:981-991.
    • (2005) J. Exp. Med. , vol.201 , pp. 981-991
    • van Rijt, L.S.1
  • 67
    • 33745036694 scopus 로고    scopus 로고
    • Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic noneosinophil cells of the innate immune system
    • Voehringer D, Reese TA, Huang X, Shinkai K, Locksley RM. 2006. Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic noneosinophil cells of the innate immune system. J. Exp. Med. 203:1435-1446.
    • (2006) J. Exp. Med. , vol.203 , pp. 1435-1446
    • Voehringer, D.1    Reese, T.A.2    Huang, X.3    Shinkai, K.4    Locksley, R.M.5
  • 68
    • 1642362240 scopus 로고    scopus 로고
    • Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production
    • Voehringer D, Shinkai K, Locksley RM. 2004. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity 20:267-277.
    • (2004) Immunity , vol.20 , pp. 267-277
    • Voehringer, D.1    Shinkai, K.2    Locksley, R.M.3
  • 69
    • 79953815551 scopus 로고    scopus 로고
    • Eosinophils sustain alternatively activated macrophages in adipose tissue
    • Wu D, et al. 2011. Eosinophils sustain alternatively activated macrophages in adipose tissue. Science 332:243-247.
    • (2011) Science , vol.332 , pp. 243-247
    • Wu, D.1
  • 70
    • 46249106875 scopus 로고    scopus 로고
    • Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages
    • e211
    • Zhao A, et al. 2008. Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology 135:217-225 e211.
    • (2008) Gastroenterology , vol.135 , pp. 217-225
    • Zhao, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.