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Volumn 31, Issue 1, 2017, Pages 7-19

Human nuclear genome transfer (So-called mitochondrial replacement): Clearing the underbrush

Author keywords

Common good; Mitochondrial disease; Mitochondrial replacement; Need; Nuclear genome transfer; Social justice; Want

Indexed keywords

MITOCHONDRIAL DNA;

EID: 85010912655     PISSN: 02699702     EISSN: 14678519     Source Type: Journal    
DOI: 10.1111/bioe.12309     Document Type: Article
Times cited : (48)

References (80)
  • 1
    • 0012590343 scopus 로고    scopus 로고
    • Is Bioethics Broke? On the Idea of Ethics and Law ‘Catching Up’ with Technology
    • M.H. Shapiro. Is Bioethics Broke? On the Idea of Ethics and Law ‘Catching Up’ with Technology. Indiana. Law Rev 1999; 33: 17-162: 30.
    • (1999) Indiana. Law Rev , vol.33 , pp. 17-162
    • Shapiro, M.H.1
  • 2
    • 85010971164 scopus 로고    scopus 로고
    • Washington, DC: The National Academies Press, [Accessed 27 Jun 2016]
    • National Academies of Sciences, Engineering, and Medicine. 2016. Mitochondrial Replacement Techniques: Ethical, Social, and Policy Considerations. Washington, DC: The National Academies Press. Available at: http://www.nap.edu/catalog/21871/mitochondrialreplacement-techniques-ethical-social-and-policy-considerations [Accessed 27 Jun 2016].
    • (2016) Mitochondrial Replacement Techniques: Ethical, Social, and Policy Considerations
  • 3
    • 84873077988 scopus 로고    scopus 로고
    • London, UK: Nuffield Council on Bioethics
    • Nuffield Council on Bioethics. 2012. Novel Techniques for the Prevention of Mitochondrial DNA Disorders: An Ethical Review. London, UK: Nuffield Council on Bioethics. Available at: http://www.nuffieldbioethics.org/sites/default/files/Novel_techniques_for_the_prevention_of_ mitochondrial_DNA_diseases_compressed.pdf/[Accessed 9 Sept 2016].
    • (2012) Novel Techniques for the Prevention of Mitochondrial DNA Disorders: An Ethical Review
  • 4
    • 70349810628 scopus 로고    scopus 로고
    • A Relational Account of Public HealThethics
    • F. Baylis, N. Kenny, & S. Sherwin. A Relational Account of Public HealThethics. Public HealThethics 2008; 1(3): 196-209: 196.
    • (2008) Public Healthethics , vol.1 , Issue.3 , pp. 196-209
    • Baylis, F.1    Kenny, N.2    Sherwin, S.3
  • 5
    • 84891541617 scopus 로고    scopus 로고
    • Three-Parent IVF: Gene Replacement for the Prevention of Inherited Mitochondrial Diseases
    • P. Amato, M. Tachibana, M. Sparman, & S. Mitalipov. Three-Parent IVF: Gene Replacement for the Prevention of Inherited Mitochondrial Diseases. Fertil Steril 2014; 101(1): 31-35.
    • (2014) Fertil Steril , vol.101 , Issue.1 , pp. 31-35
    • Amato, P.1    Tachibana, M.2    Sparman, M.3    Mitalipov, S.4
  • 6
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA Mutations in Human Disease
    • R.W. Taylor & D. Turnbull. Mitochondrial DNA Mutations in Human Disease. Nat Rev Genet 2005; 6(5): 389-402
    • (2005) Nat Rev Genet , vol.6 , Issue.5 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.2
  • 7
    • 84890382978 scopus 로고    scopus 로고
    • Mitochondrial DNA Mutation Load: Chance or Destiny?
    • S. Di Mauro. Mitochondrial DNA Mutation Load: Chance or Destiny? JAMA Neurology 2013; 70(12): 1484-1485.
    • (2013) JAMA Neurology , vol.70 , Issue.12 , pp. 1484-1485
    • Di, M.1
  • 8
    • 20344366079 scopus 로고    scopus 로고
    • Mitochondrial DNA and Disease
    • S. Dimauro & G. Davidzon. Mitochondrial DNA and Disease. Annals of Medicine 2005; 37(3): 222-232: 222.
    • (2005) Annals of Medicine , vol.37 , Issue.3 , pp. 222-232
    • Dimauro, S.1    Davidzon, G.2
  • 10
    • 70349284435 scopus 로고    scopus 로고
    • Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells
    • M. Tachibana, M. Sparman, H. Sritanaudomchai, H. Ma, L. Clepper, J. Woodward et al. Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells. Nature 2009; 461: 367-372
    • (2009) Nature , vol.461 , pp. 367-372
    • Tachibana, M.1    Sparman, M.2    Sritanaudomchai, H.3    Ma, H.4    Clepper, L.5    Woodward, J.6
  • 11
    • 77952096877 scopus 로고    scopus 로고
    • Pronuclear Transfer in Human Embryos to Prevent Transmission of MitochondrialDNA Disease
    • L. Craven, H.A. Tuppen, G.D. Greggains, S.J. Harbottle, J.L. Murphy, L.M. Cree et al. Pronuclear Transfer in Human Embryos to Prevent Transmission of MitochondrialDNA Disease. Nature 2010; 465: 82-85.
    • (2010) Nature , vol.465 , pp. 82-85
    • Craven, L.1    Tuppen, H.A.2    Greggains, G.D.3    Harbottle, S.J.4    Murphy, J.L.5    Cree, L.M.6
  • 13
    • 84981724779 scopus 로고    scopus 로고
    • Pregnancy Derived from Human Zygote Pronuclear Transfer in a Patient Who Had Arrested Embryos After IVF
    • J. Zhang, G. Zhuang, Y. Zeng, J. Grifo, C. Acosta, Y. Shu, & H. Liu. Pregnancy Derived from Human Zygote Pronuclear Transfer in a Patient Who Had Arrested Embryos After IVF. Reprod BioMed Online 2016; 33(4):529-533.
    • (2016) Reprod Biomed Online , vol.33 , Issue.4 , pp. 529-533
    • Zhang, J.1    Zhuang, G.2    Zeng, Y.3    Grifo, J.4    Acosta, C.5    Shu, Y.6    Liu, H.7
  • 14
    • 84941641809 scopus 로고    scopus 로고
    • Regulations 2015 No. 572. London, UK: The National Archives, [Accessed 8 Sept 2016]
    • United Kingdom Government. 2015. The Human Fertilisation and Embryology (Mitochondrial Donation) Regulations 2015 No. 572. London, UK: The National Archives. Available at: http://www.legislation.gov.uk/ukdsi/2015/9780111125816/contents [Accessed 8 Sept 2016].
    • (2015) The Human Fertilisation and Embryology (Mitochondrial Donation)
  • 15
    • 84878544257 scopus 로고    scopus 로고
    • The Ethics of Creating Children with Three Genetic Parents
    • F. Baylis. The Ethics of Creating Children with Three Genetic Parents. Reprod Biomed Online 2013; 26(6): 531-534.
    • (2013) Reprod Biomed Online , vol.26 , Issue.6 , pp. 531-534
    • Baylis, F.1
  • 16
    • 84978389608 scopus 로고    scopus 로고
    • What is the Value of Three-Parent IVF?
    • T. Rulli. What is the Value of Three-Parent IVF? Hastings Cent Rep 2016; 46(4): 38-47.
    • (2016) Hastings Cent Rep , vol.46 , Issue.4 , pp. 38-47
    • Rulli, T.1
  • 17
    • 84971572010 scopus 로고    scopus 로고
    • Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes
    • M. Yamada, V. Emmanuele, M.J. Sanchez-Quintero, B. Sun, G. Lallos, D. Paull et al. Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes. Cell Stem Cell 2016; 18(6): 749-754.
    • (2016) Cell Stem Cell , vol.18 , Issue.6 , pp. 749-754
    • Yamada, M.1    Emmanuele, V.2    Sanchez-Quintero, M.J.3    Sun, B.4    Lallos, G.5    Paull, D.6
  • 18
    • 85010893989 scopus 로고    scopus 로고
    • interviewed by P. Knoepfler. 9 Jun 2016. Mitochondrial Replacement Hype Goes Nuclear Including by Wellcome Trust. The Niche: Knoepfler Lab Stem Cell Blog, [Accessed 8 Sept 2016]
    • D. Egli interviewed by P. Knoepfler. 9 Jun 2016. Mitochondrial Replacement Hype Goes Nuclear Including by Wellcome Trust. The Niche: Knoepfler Lab Stem Cell Blog. Available at: http://www.ipscell. com/2016/06/mitochondrial-replacement-hype-goes-nuclear-includingby-wellcome-trust/[Accessed 8 Sept 2016].
    • Egli, D.1
  • 19
    • 84975832568 scopus 로고    scopus 로고
    • Towards Clinical Application of Pronuclear Transfer to Prevent MitochondrialDNA Disease
    • L.A. Hyslop, P. Blakeley, L. Craven, J. Richardson, N.M. Fogarty, E. Fragouli et al. Towards Clinical Application of Pronuclear Transfer to Prevent MitochondrialDNA Disease. Nature 2016; 534(7607): 383-386.
    • (2016) Nature , vol.534 , Issue.7607 , pp. 383-386
    • Hyslop, L.A.1    Blakeley, P.2    Craven, L.3    Richardson, J.4    Fogarty, N.M.5    Fragouli, E.6
  • 20
    • 85010885629 scopus 로고    scopus 로고
    • New Herbert Lab Nature Paper Reinforces Mitochondrial Replacement Achilles Heel
    • 8 Jun, [Accessed 27 Jun 2016]
    • P. Knoepfler. 8 Jun 2016. New Herbert Lab Nature Paper Reinforces Mitochondrial Replacement Achilles Heel. The Niche: Knoepfler Lab Stem Cell Blog. Available at: https://www.ipscell.com/2016/06/newnature-paper-reinforces-that-mitochondrial-replacement-has-achilles-heel/#more-19470 [Accessed 27 Jun 2016].
    • (2016) The Niche: Knoepfler Lab Stem Cell Blog
    • Knoepfler, P.1
  • 21
    • 0018263315 scopus 로고
    • Science Outpacing Ethical Studies in Genetics
    • Science Outpacing Ethical Studies in Genetics. Can Med Assoc J 1978; 119(1): 78-80
    • (1978) Can Med Assoc J , vol.119 , Issue.1 , pp. 78-80
  • 22
    • 85010848575 scopus 로고    scopus 로고
    • 10 May, As ourDNA Defines Us, Science Outpaces Ethics. Globe & Mail
    • N. Wosnick. 10 May 2012. As ourDNA Defines Us, Science Outpaces Ethics. Globe & Mail. Available at: http://www.theglobeandmail. com/opinion/as-our-dna-defines-us-science-outpaces-ethics/article4105699/[Accessed 27 Jun 2016].
    • (2012)
    • Wosnick, N.1
  • 23
    • 25844507987 scopus 로고    scopus 로고
    • Science and Society: Applications of Behavioural Genetics: Outpacing the Science?
    • M.A. Rothstein. Science and Society: Applications of Behavioural Genetics: Outpacing the Science? Nat Rev Genet 2005; 6(10): 793-798.
    • (2005) Nat Rev Genet , vol.6 , Issue.10 , pp. 793-798
    • Rothstein, M.A.1
  • 24
    • 0037984166 scopus 로고    scopus 로고
    • The Misperception that Bioethics and the Law Lag Behind Advances in Biotechnology: A Response to Michael H. Shapiro
    • D. Orentlicher. The Misperception that Bioethics and the Law Lag Behind Advances in Biotechnology: A Response to Michael H. Shapiro. Indiana Law Rev 1999; 33(1): 163-172: 164.
    • (1999) Indiana Law Rev , vol.33 , Issue.1 , pp. 163-172
    • Orentlicher, D.1
  • 25
    • 0029316832 scopus 로고
    • Germ-line Therapy to Cure Mitochondrial Disease: Protocol and Ethics of In Vitro Ovum Nuclear Transplantation
    • D.S. Rubenstein, D.C. Thomasma, E.A. Schon, & M.J. Zinaman. Germ-line Therapy to Cure Mitochondrial Disease: Protocol and Ethics of In Vitro Ovum Nuclear Transplantation. Camb Q Healthc Ethics 1995; 4(3): 316-339
    • (1995) Camb Q Healthc Ethics , vol.4 , Issue.3 , pp. 316-339
    • Rubenstein, D.S.1    Thomasma, D.C.2    Schon, E.A.3    Zinaman, M.J.4
  • 28
    • 22444452661 scopus 로고    scopus 로고
    • Transplanting Nuclei Between Human Eggs: Implications for Germ-Line Genetics
    • A.L. Bonnicksen. Transplanting Nuclei Between Human Eggs: Implications for Germ-Line Genetics. Politics the Life Sci 1998; 17(1): 3-10
    • (1998) Politics the Life Sci , vol.17 , Issue.1 , pp. 3-10
    • Bonnicksen, A.L.1
  • 29
    • 0032148940 scopus 로고    scopus 로고
    • Oocyte Cytoplasm Transfer and the Ethics of Germline Interventions
    • J.A. Robertson. Oocyte Cytoplasm Transfer and the Ethics of Germline Interventions. J Law Med Ethics 1998; 26(3): 211-220.
    • (1998) J Law Med Ethics , vol.26 , Issue.3 , pp. 211-220
    • Robertson, J.A.1
  • 30
    • 0030790458 scopus 로고    scopus 로고
    • Birth of Infant After Transfer of Anucleate Donor Oocyte Cytoplasm Into Recipient Eggs
    • J. Cohen, R. Scott, T. Schimmel, J. Levron, & S. Willadsen. Birth of Infant After Transfer of Anucleate Donor Oocyte Cytoplasm Into Recipient Eggs. Lancet 1997; 350(9072): 186-187.
    • (1997) Lancet , vol.350 , Issue.9072 , pp. 186-187
    • Cohen, J.1    Scott, R.2    Schimmel, T.3    Levron, J.4    Willadsen, S.5
  • 31
    • 0035104763 scopus 로고    scopus 로고
    • Mitochondria in Human Offspring Derived From Ooplasmic Transplantation
    • J.A. Barritt, C.A. Brenner, H.E. Malter, & J. Cohen. Mitochondria in Human Offspring Derived From Ooplasmic Transplantation. Hum Reprod 2001; 16(3): 513-516.
    • (2001) Hum Reprod , vol.16 , Issue.3 , pp. 513-516
    • Barritt, J.A.1    Brenner, C.A.2    Malter, H.E.3    Cohen, J.4
  • 32
    • 84892625112 scopus 로고    scopus 로고
    • Babies with Some Animal DNA in Them: AWoman’s Choice?
    • F. Baylis. ‘Babies with Some Animal DNA in Them’: AWoman’s Choice? Int J Fem Approaches Bioeth 2009; 2(2): 75-96.
    • (2009) Int J Fem Approaches Bioeth , vol.2 , Issue.2 , pp. 75-96
    • Baylis, F.1
  • 33
    • 0035959903 scopus 로고    scopus 로고
    • Need for Public Debate About Fertility Treatments
    • R.K. Naviaux & K.K. Singh. Need for Public Debate About Fertility Treatments. Nature 2001; 413(6854): 347
    • (2001) Nature , vol.413 , Issue.6854 , pp. 347
    • Naviaux, R.K.1    Singh, K.K.2
  • 34
    • 0035917855 scopus 로고    scopus 로고
    • Inadvertently Crossing the Germ Line
    • E. Parens & E. Juengst. Inadvertently Crossing the Germ Line. Science 2001; 292(5516): 397
    • (2001) Science , vol.292 , Issue.5516 , pp. 397
    • Parens, E.1    Juengst, E.2
  • 35
    • 0037035118 scopus 로고    scopus 로고
    • Ooplasmic Transfer—Proceed with Care
    • A. Templeton. Ooplasmic Transfer—Proceed with Care. N Engl J Med 2002; 346: 773-775.
    • (2002) N Engl J Med , vol.346 , pp. 773-775
    • Templeton, A.1
  • 36
    • 85010885610 scopus 로고    scopus 로고
    • at LIFE for Mitochondrial Research. 8 Sept 2015. London, UK: Human Fertilisation & Embryology Authority, [Accessed 27 Jun 2016]
    • HFEA Grants Licence to Newcastle Centre at LIFE for Mitochondrial Research. 8 Sept 2015. London, UK: Human Fertilisation & Embryology Authority. Available at: http://www.hfea.gov.uk/671.html [Accessed 27 Jun 2016].
  • 37
    • 78651395112 scopus 로고    scopus 로고
    • Ethics of Mitochondrial Gene Replacement: From Bench to Bedside
    • A. Bredenoord & P. Braude. Ethics of Mitochondrial Gene Replacement: From Bench to Bedside. Br Med J 2011; 342: 87-89
    • (2011) Br Med J , vol.342 , pp. 87-89
    • Bredenoord, A.1    Braude, P.2
  • 39
    • 84943199269 scopus 로고    scopus 로고
    • The Ethical Challenges of the Clinical Introduction of Mitochondrial Replacement Techniques
    • J.B. Appleby. The Ethical Challenges of the Clinical Introduction of Mitochondrial Replacement Techniques. Med Health Care Philos 2015; 189(4): 501-514.
    • (2015) Med Health Care Philos , vol.189 , Issue.4 , pp. 501-514
    • Appleby, J.B.1
  • 40
    • 85010848593 scopus 로고    scopus 로고
    • Newcastle, UK: Newcastle upon Tyne Hospitals, NHS Foundation Trust, [Accessed 27 Jun 2016]
    • Newcastle Fertility Centre. 2016. Mitochondrial Transmission. Newcastle, UK: Newcastle upon Tyne Hospitals, NHS Foundation Trust. Available at: http://www.newcastle-hospitals.org.uk/services/fertilitycentre_ research-and-technology_mitochondrial-transmission.aspx [Accessed 27 Jun 2016].
    • (2016) Mitochondrial Transmission
  • 41
    • 84922947421 scopus 로고    scopus 로고
    • Mitochondrial Replacement Therapy in Reproductive Medicine
    • D.P. Wolf, N. Mitalipov, & S. Mitalipov. Mitochondrial Replacement Therapy in Reproductive Medicine. Trends Mol Med 2015; 21(2): 68-76: 75.
    • (2015) Trends Mol Med , vol.21 , Issue.2 , pp. 68-76
    • Wolf, D.P.1    Mitalipov, N.2    Mitalipov, S.3
  • 42
    • 85010911369 scopus 로고    scopus 로고
    • 25-26 Feb 2014. Briefing document, Cellular, Tissue, and Gene Therapies Advisory Committee. Meeting #59 Oocyte Modification in Assisted Reproduction for the Prevention of Transmission of Mitochondrial Disease or Treatment of Infertility, [Accessed 27 Jun 2016]
    • Food and Drug Administration. 25-26 Feb 2014. Briefing document, Cellular, Tissue, and Gene Therapies Advisory Committee. Meeting #59 Oocyte Modification in Assisted Reproduction for the Prevention of Transmission of Mitochondrial Disease or Treatment of Infertility. Available at: http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeeting Materials/BloodVaccinesandOtherBiologics/CellularTissueandGeneTherapiesAdvisoryCommittee/UCM385461.pdf [Accessed 27 Jun 2016].
  • 43
    • 85010839079 scopus 로고    scopus 로고
    • Code of Practice, 8Thedition. Oct, London, UK: Human Fertilisation & Embryology Authority, [Accessed 27 Jun 2016]
    • Human Fertilisation & Embryology Authority. Code of Practice, 8Thedition. Oct 2015. London, UK: Human Fertilisation & Embryology Authority. Available at: http://www.hfea.gov.uk/docs/HFEA_Code_of_ Practice:8th_Edtion_(Oct_2015).pdf [Accessed 27 Jun 2016].
    • (2015)
  • 44
    • 84960344906 scopus 로고    scopus 로고
    • The Other Woman: Evaluating the Language of _Three Parent_ Embryos
    • D. Jones. The Other Woman: Evaluating the Language of _Three Parent_ Embryos. Clin Ethics 2015; 10(4): 97-106.
    • (2015) Clin Ethics , vol.10 , Issue.4 , pp. 97-106
    • Jones, D.1
  • 45
    • 85009460886 scopus 로고    scopus 로고
    • Rendered Invisible? The Absent Presence of Egg Providers in U.K
    • Debates on the Acceptability of Research and Therapy for Mitochondrial Disease
    • E. Haimes & K. Taylor. Rendered Invisible? The Absent Presence of Egg Providers in U.K. Debates on the Acceptability of Research and Therapy for Mitochondrial Disease. Monash Bioeth Rev 2015; 33(4): 360-378: 364-365.
    • (2015) Monash Bioeth Rev , vol.33 , Issue.4
    • Haimes, E.1    Taylor, K.2
  • 46
    • 84956956235 scopus 로고    scopus 로고
    • The Latest Thorn by Any Other Name: Germ-Line Nuclear Transfer in the Name of ‘Mitochondrial Replacement’
    • J. Nisker. The Latest Thorn by Any Other Name: Germ-Line Nuclear Transfer in the Name of ‘Mitochondrial Replacement’. J Obstet Gynaecol Can 2015; 37(9): 829-831: 829.
    • (2015) J Obstet Gynaecol Can , vol.37 , Issue.9
    • Nisker, J.1
  • 47
    • 84956956235 scopus 로고    scopus 로고
    • The Latest Thorn by Any Other Name: Germ-Line Nuclear Transfer in the Name of ‘Mitochondrial Replacement’
    • J. Nisker. The Latest Thorn by Any Other Name: Germ-Line Nuclear Transfer in the Name of ‘Mitochondrial Replacement’. J Obstet Gynaecol Can 2015; 37(9): 830.
    • (2015) J Obstet Gynaecol Can , vol.37 , Issue.9 , pp. 830
    • Nisker, J.1
  • 48
    • 84878569940 scopus 로고    scopus 로고
    • Radical Rupture: Exploring Biological Sequelae of Volitional Inheritable Genetic Modification
    • In J.E.J. Rasko, G.M. O’Sullivan, & R.A. Ankeny, eds., Cambridge: Cambridge University Press
    • F. Baylis & J.S. Robert. 2005. Radical Rupture: Exploring Biological Sequelae of Volitional Inheritable Genetic Modification. In J.E.J. Rasko, G.M. O’Sullivan, & R.A. Ankeny, eds. The Ethics of Inheritable Genetic Modification. Cambridge: Cambridge University Press: 131-148.
    • (2005) The Ethics of Inheritable Genetic Modification , pp. 131-148
    • Baylis, F.1    Robert, J.S.2
  • 49
    • 85010850927 scopus 로고    scopus 로고
    • Accessed 27 Jun 2016
    • The Truth about Mitochondrial Replacement. Impact Ethics. Available at: http://impactethics. ca/2015/02/23/the-truth-about-mitochondrial-replacement/[Accessed 27 Jun 2016]
  • 50
    • 85010856560 scopus 로고    scopus 로고
    • Ethical Objections to Mitochondrial Replacement
    • 2 Jul, [Accessed 27 Jun 2016]
    • F. Baylis. 2 Jul 2013. Ethical Objections to Mitochondrial Replacement. Impact Ethics. Available at: http://impactethics.ca/2013/07/02/ethical-objections-to-mitochondrial-replacement/[Accessed 27 Jun 2016].
    • (2013) Impact Ethics
    • Baylis, F.1
  • 51
    • 85010853574 scopus 로고    scopus 로고
    • Three-parent Babies: How the Future of FertilityWill Challenge Ideas of Parenthood
    • 23 Dec, [Accessed 27 Jun 2016]
    • S. Kirkey. 23 Dec 2015. Three-parent Babies: How the Future of FertilityWill Challenge Ideas of Parenthood. National Post. Available at: http://news.nationalpost.com/news/canada/three-parent-babies [Accessed 27 Jun 2016].
    • (2015) National Post
    • Kirkey, S.1
  • 53
    • 77951880598 scopus 로고    scopus 로고
    • The Medicalization of Reproduction-A 30 Year Retrospective
    • Reprogen-Ethics and the Future of Gender. Published online by Springer as International Library of Ethics, Law, and the New Medicine 2009, [Accessed 9 Sept 2016]
    • S. Holm. The Medicalization of Reproduction-A 30 Year Retrospective. In F. Simonstein, ed. 2009. Reprogen-Ethics and the Future of Gender. Published online by Springer as International Library of Ethics, Law, and the New Medicine 2009; 43: 29-36. Available at: http://link.springer. com/book/10.1007%2F978-90-481-2475-6 [Accessed 9 Sept 2016].
    • (2009) Simonstein , vol.43 , pp. 29-36
    • Holm, S.1
  • 54
    • 2842601485 scopus 로고
    • Englewood Cliffs, NJ: Prentice Hall
    • M.D. Bayles. 1984. Reproductive Ethics. Englewood Cliffs, NJ: Prentice Hall: 13.
    • (1984) Reproductive Ethics , pp. 13
    • Bayles, M.D.1
  • 55
    • 0002220358 scopus 로고
    • Deconstructing ‘Desperateness’: The Social Construction of Infertility in Popular Representations of New Reproductive Technologies
    • M. McNeil, I. Varco, & S. Yearley, eds, London, UK: Palgrave Macmillan UK: 200-229
    • S. Franklin. 1990. Deconstructing ‘Desperateness’: The Social Construction of Infertility in Popular Representations of New Reproductive Technologies. In M. McNeil, I. Varco, & S. Yearley, eds. The New Reproductive Technologies. London, UK: Palgrave Macmillan UK: 200-229: 207.
    • (1990) The New Reproductive Technologies , pp. 207
    • Franklin, S.1
  • 56
    • 0015222881 scopus 로고
    • Social Values and Research in Human Embryology
    • R.G. Edwards & D.J. Sharpe. Social Values and Research in Human Embryology. Nature 1971; 231(5298): 87-91: 87.
    • (1971) Nature , vol.231 , Issue.5298
    • Edwards, R.G.1    Sharpe, D.J.2
  • 57
    • 0029417602 scopus 로고
    • The Genetic Tie
    • D.E. Roberts. The Genetic Tie. Univ Chic Law Rev 1995; 62(1): 209-273: 215.
    • (1995) Univ Chic Law Rev , vol.62 , Issue.1 , pp. 209-273
    • Roberts, D.E.1
  • 58
  • 59
    • 52749098816 scopus 로고    scopus 로고
    • Philos Public Aff
    • J.D. Velleman. Persons in Prospect. Philos Public Aff2008; 36(3): 221-288.
    • (2008) Persons in Prospect , vol.36 , Issue.3 , pp. 221-288
    • Velleman, J.D.1
  • 60
    • 84961808926 scopus 로고    scopus 로고
    • ACritique of the Bionormative Concept of the Family
    • In F. Baylis & C. McLeod, eds., Oxford: Oxford University Press
    • C. Witt. 2014. ACritique of the Bionormative Concept of the Family. In F. Baylis & C. McLeod, eds. Family-Making: Contemporary Ethical Challenges. Oxford: Oxford University Press: 49-63.
    • (2014) Family-Making: Contemporary Ethical Challenges , pp. 49-63
    • Witt, C.1
  • 61
    • 84998679629 scopus 로고    scopus 로고
    • Preferring a Genetically-Related Child
    • [Accessed 9 Sept 2016]
    • T. Rulli. Preferring a Genetically-Related Child. J Moral Philos Nov 2014; DOI: 10.1163/17455243-4681062: 1-30. Available at: http://trulli. faculty.ucdavis.edu/wp-content/uploads/sites/86/2014/07/17455243_46 81062_text.pdf [Accessed 9 Sept 2016].
    • (2014) J Moral Philos Nov , pp. 1-30
    • Rulli, T.1
  • 63
    • 85010850942 scopus 로고    scopus 로고
    • Review panel chair. Jun 2014. Third Scientific Review of the Safety and Efficacy of Methods to Avoid Mitochondrial Disease through Assisted Conception: 2014 Update. London, UK: Human Fertilisation & Embryology Authority, [Accessed 27 Jun 2016]
    • A. Greenfield— Review panel chair. Jun 2014. Third Scientific Review of the Safety and Efficacy of Methods to Avoid Mitochondrial Disease through Assisted Conception: 2014 Update. London, UK: Human Fertilisation & Embryology Authority. Available at: http://www.hfea.gov. uk/docs/Third_Mitochondrial_replacement_scientific_review.pdf [Accessed 27 Jun 2016]
    • Greenfield, A.1
  • 64
    • 84923263223 scopus 로고    scopus 로고
    • Concise Reviews: Assisted Reproductive Technologies to Prevent Transmission of Mitochondrial DNA Disease
    • J. Richardson, L. Irving, L.A. Hyslop, M. Choudhary, A. Murdoch, D. Turnbull, & M. Herbert. Concise Reviews: Assisted Reproductive Technologies to Prevent Transmission of Mitochondrial DNA Disease. Stem Cells 2015; 33(3): 639-645.
    • (2015) Stem Cells , vol.33 , Issue.3 , pp. 639-645
    • Richardson, J.1    Irving, L.2    Hyslop, L.A.3    Choudhary, M.4    Murdoch, A.5    Turnbull, D.6    Herbert, M.7
  • 66
    • 85010888378 scopus 로고    scopus 로고
    • Jun 2011. Newcastle Mitochondrial Disease Guidelines: Pregnancy in Mitochondrial Disease, [Accessed 27 Jun 2016]
    • H. Turnbull, R. Say, M. Smith, V. Nesbitt, R. McFarland, D. Turnbull, & M. Schaefer—The Guideline Development Group. Jun 2011. Newcastle Mitochondrial Disease Guidelines: Pregnancy in Mitochondrial Disease. Available at: http://www.mitochondrialncg.nhs.uk/documents/Pregnancy_Guidelines_%202011.pdf [Accessed 27 Jun 2016].
    • The Guideline Development Group
    • Turnbull, H.1    Say, R.2    Smith, M.3    Nesbitt, V.4    McFarland, R.5    Turnbull, D.6    Schaefer, M.7
  • 67
    • 84956670822 scopus 로고    scopus 로고
    • Access to and Use of Infertility Services in the United States: Framing the Challenges
    • E.Y. Adashi & L.A. Dean. Access to and Use of Infertility Services in the United States: Framing the Challenges. Fertil Steril 2016; 105(5): 1113-1118.
    • (2016) Fertil Steril , vol.105 , Issue.5 , pp. 1113-1118
    • Adashi, E.Y.1
  • 69
    • 85010862717 scopus 로고    scopus 로고
    • London, UK: Queen Square for Neuromuscular Diseases, [Accessed 9 Sept 2016]
    • University College London. 2016. Incidence of Complications of Pregnancy in Patients Diagnosed with Mitochondrial Disease or Carrying a Mitochondrial DNA Mutation. London, UK: Queen Square for Neuromuscular Diseases. Available at: http://www.cnmd.ac.uk/research/clinical_ trial/incidence-of-complications-of-pregnancy-in-patients-diagnosed-with-mitochondrial-disease-or-carrying-a-mitochondrialdna-mutation [Accessed 9 Sept 2016].
    • (2016) Incidence of Complications of Pregnancy in Patients Diagnosed with Mitochondrial Disease Or Carrying a Mitochondrial DNA Mutation
  • 70
    • 85010900521 scopus 로고    scopus 로고
    • [Accessed 16 Nov 2016]
    • American Society for Reproductive Medicine. Fact Sheet: Side Effects of Injectable Fertility Drugs (Gonadotropins). Available at: http://www.reproductivefacts.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/Gonadatrophins-Fact. pdf [Accessed 16 Nov 2016].
    • Fact Sheet: Side Effects of Injectable Fertility Drugs
  • 71
    • 0034944751 scopus 로고    scopus 로고
    • Social Determinants of HumanReproduction
    • The ESHRE Capri Workshop Group. Social Determinants of HumanReproduction. Hum Reprod 2001; 16(7): 1518-1526.
    • (2001) Hum Reprod , vol.16 , Issue.7 , pp. 1518-1526
  • 72
    • 34447316145 scopus 로고    scopus 로고
    • Potential Need and Demand for Infertility Medical Care
    • International Estimates of Infertility Prevalence and Treatment-Seeking
    • J. Boivin, L. Bunting, J.A. Collins, & K. Nygren. International Estimates of Infertility Prevalence and Treatment-Seeking: Potential Need and Demand for Infertility Medical Care. Hum Reprod 2007; 22(6): 1506-1512.
    • (2007) Hum Reprod , vol.22 , Issue.6 , pp. 1506-1512
    • Boivin, J.1    Bunting, L.2    Collins, J.A.3    Nygren, K.4
  • 73
    • 84904412645 scopus 로고    scopus 로고
    • Infertility Service Use in the United States: Data from the National Survey of Family Growth, 1982-2010
    • 22 Jan
    • A. Chandra, C.E. Copen, & E.H. Stephen. Infertility Service Use in the United States: Data from the National Survey of Family Growth, 1982-2010. National Health Statistics Report 22 Jan 2014; 73: 1-21.
    • (2014) National Health Statistics Report , Issue.73 , pp. 1-21
    • Chandra, A.1    Copen, C.E.2    Stephen, E.H.3
  • 74
    • 84971633603 scopus 로고    scopus 로고
    • London, UK: Human Fertilisation & Embryology Authority: 17, Accessed 9 Sept 2016]
    • Human Fertilisation & Embryology Authority. 2013. Fertility Treatment in 2013: Trends and Figures. London, UK: Human Fertilisation & Embryology Authority: 17. Available at: http://www.hfea.gov.uk/docs/HFEA_Fertility_Trends_and_Figures_2013.pdf [Accessed 9 Sept 2016].
    • (2013) Fertility Treatment in 2013: Trends and Figures
  • 75
    • 67349222715 scopus 로고    scopus 로고
    • 2015, [Accessed 27 Jun 2016]
    • Centers for Disease Control and Prevention. 2013 Assisted Reproductive Technology Fertility Clinic Success Rates Report. 2015. Available at: ftp://ftp.cdc.gov/pub/Publications/art/ART-2013-Clinic-Report-Full.pdf [Accessed 27 Jun 2016].
    • (2013) Assisted Reproductive Technology Fertility Clinic Success Rates Report
  • 76
    • 85010852609 scopus 로고    scopus 로고
    • Scientists Face New Ethics Quandaries in Baby-Making
    • 19 Aug, [Accessed 27 Jun 2016]
    • G. Kolata. 19 Aug 1997. Scientists Face New Ethics Quandaries in Baby-Making. New York Times. Available at: http://www.nytimes. com/1997/08/19/science/scientists-face-new-ethical-quandaries-in-babymaking. html?pagewanted5all [Accessed 27 Jun 2016].
    • (1997) New York Times
    • Kolata, G.1
  • 77
    • 85029323505 scopus 로고    scopus 로고
    • Scientist Who Pioneered ‘Three-parent’ IVF Embryo Technique NowWants to Offer it to OlderWomen Trying for a Baby
    • 7 Feb, [Accessed 9 Sept 2016]
    • S. Connor. 7 Feb 2015. Scientist Who Pioneered ‘Three-parent’ IVF Embryo Technique NowWants to Offer it to OlderWomen Trying for a Baby. Independent. Available at: http://www.independent.co.uk/news/science/three-parent-embryos-an-ivf-revolution-or-a-slippery-slope-todesigner-babies-10031477.html [Accessed 9 Sept 2016].
    • (2015) Independent
    • Connor, S.1
  • 79
    • 85010848984 scopus 로고    scopus 로고
    • Why we should have fewer children: To save the planet
    • 12 Sept, [Accessed 14 Sept 2016]
    • T.N. Reider. 12 Sept 2016. Why we should have fewer children: to save the planet. The Guardian. Available at: https://www.theguardian.com/commentisfree/2016/sep/12/why-we-should-have-fewer-children-savethe-planet-climate-change [Accessed 14 Sept 2016].
    • (2016) The Guardian
    • Reider, T.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.