메뉴 건너뛰기




Volumn 21, Issue 2, 2015, Pages 68-76

Mitochondrial replacement therapy in reproductive medicine

Author keywords

Female infertility; Mitochondria; Mitochondrial DNA; Mitochondrial replacement therapy

Indexed keywords

MITOCHONDRIAL DNA;

EID: 84922947421     PISSN: 14714914     EISSN: 1471499X     Source Type: Journal    
DOI: 10.1016/j.molmed.2014.12.001     Document Type: Review
Times cited : (136)

References (51)
  • 1
    • 84907679306 scopus 로고    scopus 로고
    • The micromanagers
    • Hamilton G. The micromanagers. New Sci. 2014, 223:42-45.
    • (2014) New Sci. , vol.223 , pp. 42-45
    • Hamilton, G.1
  • 2
    • 84901382660 scopus 로고    scopus 로고
    • Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease
    • Wallace D.C., Chalkia D. Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease. Cold Spring Harb. Perspect. Med. 2013, 3:a021220.
    • (2013) Cold Spring Harb. Perspect. Med. , vol.3 , pp. a021220
    • Wallace, D.C.1    Chalkia, D.2
  • 4
    • 0024242545 scopus 로고
    • Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy
    • Wallace D.C., et al. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 1988, 242:1427-1430.
    • (1988) Science , vol.242 , pp. 1427-1430
    • Wallace, D.C.1
  • 5
    • 0023813744 scopus 로고
    • Deletions of mitochondrial DNA in Kearns-Sayre syndrome
    • Zeviani M., et al. Deletions of mitochondrial DNA in Kearns-Sayre syndrome. Neurology 1988, 38:1339-1346.
    • (1988) Neurology , vol.38 , pp. 1339-1346
    • Zeviani, M.1
  • 6
    • 48349097445 scopus 로고    scopus 로고
    • Pathogenic mitochondrial DNA mutations are common in the general population
    • Elliott H.R., et al. Pathogenic mitochondrial DNA mutations are common in the general population. Am. J. Hum. Genet. 2008, 83:254-260.
    • (2008) Am. J. Hum. Genet. , vol.83 , pp. 254-260
    • Elliott, H.R.1
  • 7
    • 84901199108 scopus 로고    scopus 로고
    • Limitations of preimplantation genetic diagnosis for mitochondrial DNA diseases
    • Mitalipov S., et al. Limitations of preimplantation genetic diagnosis for mitochondrial DNA diseases. Cell Rep. 2014, 7:935-937.
    • (2014) Cell Rep. , vol.7 , pp. 935-937
    • Mitalipov, S.1
  • 8
    • 0020519385 scopus 로고
    • Nuclear transplantation in the mouse embryo by microsurgery and cell fusion
    • McGrath J., Solter D. Nuclear transplantation in the mouse embryo by microsurgery and cell fusion. Science 1983, 220:1300-1302.
    • (1983) Science , vol.220 , pp. 1300-1302
    • McGrath, J.1    Solter, D.2
  • 9
    • 28044448512 scopus 로고    scopus 로고
    • Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation
    • Sato A., et al. Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:16765-16770.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 16765-16770
    • Sato, A.1
  • 10
    • 0031025813 scopus 로고    scopus 로고
    • Mitochondrial genotype segregation in a mouse heteroplasmic lineage produced by embryonic karyoplast transplantation
    • Meirelles F.V., Smith L.C. Mitochondrial genotype segregation in a mouse heteroplasmic lineage produced by embryonic karyoplast transplantation. Genetics 1997, 145:445-451.
    • (1997) Genetics , vol.145 , pp. 445-451
    • Meirelles, F.V.1    Smith, L.C.2
  • 11
    • 0031887449 scopus 로고    scopus 로고
    • Mitochondrial genotype segregation during preimplantation development in mouse heteroplasmic embryos
    • Meirelles F.V., Smith L.C. Mitochondrial genotype segregation during preimplantation development in mouse heteroplasmic embryos. Genetics 1998, 148:877-883.
    • (1998) Genetics , vol.148 , pp. 877-883
    • Meirelles, F.V.1    Smith, L.C.2
  • 12
    • 84903127483 scopus 로고    scopus 로고
    • Polar body genome transfer for preventing the transmission of inherited mitochondrial diseases
    • Wang T., et al. Polar body genome transfer for preventing the transmission of inherited mitochondrial diseases. Cell 2014, 157:1591-1604.
    • (2014) Cell , vol.157 , pp. 1591-1604
    • Wang, T.1
  • 13
    • 0033653708 scopus 로고    scopus 로고
    • Mitochondrial morphology during preimplantational human embryogenesis
    • Sathananthan A.H., Trounson A.O. Mitochondrial morphology during preimplantational human embryogenesis. Hum. Reprod. 2000, 15(Suppl. 2):148-159.
    • (2000) Hum. Reprod. , vol.15 , pp. 148-159
    • Sathananthan, A.H.1    Trounson, A.O.2
  • 14
    • 0034532015 scopus 로고    scopus 로고
    • Differential mitochondrial distribution in human pronuclear embryos leads to disproportionate inheritance between blastomeres: relationship to microtubular organization, ATP content and competence
    • Van Blerkom J., et al. Differential mitochondrial distribution in human pronuclear embryos leads to disproportionate inheritance between blastomeres: relationship to microtubular organization, ATP content and competence. Hum. Reprod. 2000, 15:2621-2633.
    • (2000) Hum. Reprod. , vol.15 , pp. 2621-2633
    • Van Blerkom, J.1
  • 15
    • 84874301669 scopus 로고    scopus 로고
    • Preventing the transmission of pathogenic mitochondrial DNA mutations: Can we achieve long-term benefits from germ-line gene transfer?
    • Samuels D.C., et al. Preventing the transmission of pathogenic mitochondrial DNA mutations: Can we achieve long-term benefits from germ-line gene transfer?. Hum. Reprod. 2013, 28:554-559.
    • (2013) Hum. Reprod. , vol.28 , pp. 554-559
    • Samuels, D.C.1
  • 16
    • 77952096877 scopus 로고    scopus 로고
    • Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease
    • Craven L., et al. Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease. Nature 2010, 465:82-85.
    • (2010) Nature , vol.465 , pp. 82-85
    • Craven, L.1
  • 17
    • 70349284435 scopus 로고    scopus 로고
    • Mitochondrial gene replacement in primate offspring and embryonic stem cells
    • Tachibana M., et al. Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature 2009, 461:367-372.
    • (2009) Nature , vol.461 , pp. 367-372
    • Tachibana, M.1
  • 18
    • 84861699019 scopus 로고    scopus 로고
    • Rapid mitochondrial DNA segregation in primate preimplantation embryos precedes somatic and germline bottleneck
    • Lee H.S., et al. Rapid mitochondrial DNA segregation in primate preimplantation embryos precedes somatic and germline bottleneck. Cell Rep. 2012, 1:506-515.
    • (2012) Cell Rep. , vol.1 , pp. 506-515
    • Lee, H.S.1
  • 19
    • 77956677770 scopus 로고    scopus 로고
    • Chromosome transfer in mature oocytes
    • Tachibana M., et al. Chromosome transfer in mature oocytes. Nat. Protoc. 2010, 5:1138-1147.
    • (2010) Nat. Protoc. , vol.5 , pp. 1138-1147
    • Tachibana, M.1
  • 20
    • 84873054632 scopus 로고    scopus 로고
    • Chromosome transfer in mature oocytes
    • Tachibana M., et al. Chromosome transfer in mature oocytes. Fertil. Steril. 2012, 97:e16.
    • (2012) Fertil. Steril. , vol.97 , pp. e16
    • Tachibana, M.1
  • 21
    • 84873099821 scopus 로고    scopus 로고
    • Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants
    • Paull D., et al. Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants. Nature 2013, 493:632-637.
    • (2013) Nature , vol.493 , pp. 632-637
    • Paull, D.1
  • 22
    • 84873088209 scopus 로고    scopus 로고
    • Towards germline gene therapy of inherited mitochondrial diseases
    • Tachibana M., et al. Towards germline gene therapy of inherited mitochondrial diseases. Nature 2013, 493:627-631.
    • (2013) Nature , vol.493 , pp. 627-631
    • Tachibana, M.1
  • 23
    • 0031798789 scopus 로고    scopus 로고
    • The first polar body can be used for the production of normal offspring in mice
    • Wakayama T., Yanagimachi R. The first polar body can be used for the production of normal offspring in mice. Biol. Reprod. 1998, 59:100-104.
    • (1998) Biol. Reprod. , vol.59 , pp. 100-104
    • Wakayama, T.1    Yanagimachi, R.2
  • 24
    • 0030823511 scopus 로고    scopus 로고
    • Participation of the female pronucleus derived from the second polar body in full embryonic development of mice
    • Wakayama T., et al. Participation of the female pronucleus derived from the second polar body in full embryonic development of mice. J. Reprod. Fertil. 1997, 110:263-266.
    • (1997) J. Reprod. Fertil. , vol.110 , pp. 263-266
    • Wakayama, T.1
  • 25
    • 84896279403 scopus 로고    scopus 로고
    • Concise review: parthenote stem cells for regenerative medicine: genetic, epigenetic, and developmental features
    • Daughtry B., Mitalipov S. Concise review: parthenote stem cells for regenerative medicine: genetic, epigenetic, and developmental features. Stem Cells Transl. Med. 2014, 3:290-298.
    • (2014) Stem Cells Transl. Med. , vol.3 , pp. 290-298
    • Daughtry, B.1    Mitalipov, S.2
  • 26
    • 34548570275 scopus 로고    scopus 로고
    • Zygotic gene activation and maternal factors in mammals
    • Minami N., et al. Zygotic gene activation and maternal factors in mammals. J. Reprod. Dev. 2007, 53:707-715.
    • (2007) J. Reprod. Dev. , vol.53 , pp. 707-715
    • Minami, N.1
  • 27
    • 0026469157 scopus 로고
    • Gene expression in pre-implantation mammalian embryos
    • Schultz G.A., Heyner S. Gene expression in pre-implantation mammalian embryos. Mutat. Res. 1992, 296:17-31.
    • (1992) Mutat. Res. , vol.296 , pp. 17-31
    • Schultz, G.A.1    Heyner, S.2
  • 28
    • 33947327049 scopus 로고    scopus 로고
    • Maternal microRNAs are essential for mouse zygotic development
    • Tang F., et al. Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007, 21:644-648.
    • (2007) Genes Dev. , vol.21 , pp. 644-648
    • Tang, F.1
  • 29
    • 0029143693 scopus 로고
    • Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women
    • Keefe D.L., et al. Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women. Fertil. Steril. 1995, 64:577-583.
    • (1995) Fertil. Steril. , vol.64 , pp. 577-583
    • Keefe, D.L.1
  • 30
    • 0035025276 scopus 로고    scopus 로고
    • Mitochondrial aggregation patterns and activity in human oocytes and preimplantation embryos
    • Wilding M., et al. Mitochondrial aggregation patterns and activity in human oocytes and preimplantation embryos. Hum. Reprod. 2001, 16:909-917.
    • (2001) Hum. Reprod. , vol.16 , pp. 909-917
    • Wilding, M.1
  • 31
    • 0028918729 scopus 로고
    • ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer
    • Van Blerkom J., et al. ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer. Hum. Reprod. 1995, 10:415-424.
    • (1995) Hum. Reprod. , vol.10 , pp. 415-424
    • Van Blerkom, J.1
  • 32
    • 79961207245 scopus 로고    scopus 로고
    • Mitochondrial function in the human oocyte and embryo and their role in developmental competence
    • Van Blerkom J. Mitochondrial function in the human oocyte and embryo and their role in developmental competence. Mitochondrion 2011, 11:797-813.
    • (2011) Mitochondrion , vol.11 , pp. 797-813
    • Van Blerkom, J.1
  • 33
    • 79951566236 scopus 로고    scopus 로고
    • Mitochondria DNA deletion and copy numbers of cumulus cells associated with in vitro fertilization outcomes
    • Tsai H.D., et al. Mitochondria DNA deletion and copy numbers of cumulus cells associated with in vitro fertilization outcomes. J. Reprod. Med. 2010, 55:491-497.
    • (2010) J. Reprod. Med. , vol.55 , pp. 491-497
    • Tsai, H.D.1
  • 34
    • 0033659131 scopus 로고    scopus 로고
    • Chromosomal non-disjunction in human oocytes: is there a mitochondrial connection?
    • Schon E.A., et al. Chromosomal non-disjunction in human oocytes: is there a mitochondrial connection?. Hum. Reprod. 2000, Suppl. 2:160-172.
    • (2000) Hum. Reprod. , vol.Suppl. 2 , pp. 160-172
    • Schon, E.A.1
  • 35
    • 79959404400 scopus 로고    scopus 로고
    • Age related changes in mitochondrial function and new approaches to study redox regulation in mammalian oocytes in response to age or maturation conditions
    • Eichenlaub-Ritter U., et al. Age related changes in mitochondrial function and new approaches to study redox regulation in mammalian oocytes in response to age or maturation conditions. Mitochondrion 2011, 5:783-796.
    • (2011) Mitochondrion , vol.5 , pp. 783-796
    • Eichenlaub-Ritter, U.1
  • 36
    • 0005775688 scopus 로고    scopus 로고
    • Ooplasmic transfer in mature human oocytes
    • Cohen J., et al. Ooplasmic transfer in mature human oocytes. Mol. Hum. Reprod. 1998, 4:269-280.
    • (1998) Mol. Hum. Reprod. , vol.4 , pp. 269-280
    • Cohen, J.1
  • 37
    • 85009707036 scopus 로고    scopus 로고
    • Neonatal risks from in vitro fertilization and delayed motherhood
    • Bellieni C.V. Neonatal risks from in vitro fertilization and delayed motherhood. World J. Clin. Pediatr. 2012, 1:34-36.
    • (2012) World J. Clin. Pediatr. , vol.1 , pp. 34-36
    • Bellieni, C.V.1
  • 38
    • 33748777101 scopus 로고    scopus 로고
    • Pregnancy in patients of advanced maternal age
    • Braveman F.R. Pregnancy in patients of advanced maternal age. Anesthesiol. Clin. 2006, 24:637-646.
    • (2006) Anesthesiol. Clin. , vol.24 , pp. 637-646
    • Braveman, F.R.1
  • 39
    • 66249115278 scopus 로고    scopus 로고
    • The effect of in vitro fertilization on birth rates in western countries
    • Habbema J.D., et al. The effect of in vitro fertilization on birth rates in western countries. Hum. Reprod. 2009, 24:1414-1419.
    • (2009) Hum. Reprod. , vol.24 , pp. 1414-1419
    • Habbema, J.D.1
  • 40
    • 0032963731 scopus 로고    scopus 로고
    • Reconstituting eggs: the ethics of cytoplasm donation
    • Robertson J.A. Reconstituting eggs: the ethics of cytoplasm donation. Fertil. Steril. 1999, 71:219-221.
    • (1999) Fertil. Steril. , vol.71 , pp. 219-221
    • Robertson, J.A.1
  • 41
    • 84901332340 scopus 로고    scopus 로고
    • The challenges of mitochondrial replacement
    • Chinnery P.F., et al. The challenges of mitochondrial replacement. PLoS Genet. 2014, 10:e1004315.
    • (2014) PLoS Genet. , vol.10 , pp. e1004315
    • Chinnery, P.F.1
  • 42
    • 84884643465 scopus 로고    scopus 로고
    • Medicine. Mitochondrial replacement, evolution, and the clinic
    • Reinhardt K., et al. Medicine. Mitochondrial replacement, evolution, and the clinic. Science 2013, 341:1345-1346.
    • (2013) Science , vol.341 , pp. 1345-1346
    • Reinhardt, K.1
  • 43
    • 0031944594 scopus 로고    scopus 로고
    • Decreased physical performance of congenic mice with mismatch between the nuclear and the mitochondrial genome
    • Nagao Y., et al. Decreased physical performance of congenic mice with mismatch between the nuclear and the mitochondrial genome. Genes Genet. Syst. 1998, 73:21-27.
    • (1998) Genes Genet. Syst. , vol.73 , pp. 21-27
    • Nagao, Y.1
  • 44
    • 0041854274 scopus 로고    scopus 로고
    • Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice
    • Roubertoux P.L., et al. Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice. Nat. Genet. 2003, 35:65-69.
    • (2003) Nat. Genet. , vol.35 , pp. 65-69
    • Roubertoux, P.L.1
  • 45
    • 0029816795 scopus 로고    scopus 로고
    • Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA
    • Jenuth J.P., et al. Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA. Nat. Genet. 1996, 14:146-151.
    • (1996) Nat. Genet. , vol.14 , pp. 146-151
    • Jenuth, J.P.1
  • 46
    • 84861560631 scopus 로고    scopus 로고
    • Consistent and predictable delivery rates after oocyte vitrification: an observational longitudinal cohort multicentric study
    • Rienzi L., et al. Consistent and predictable delivery rates after oocyte vitrification: an observational longitudinal cohort multicentric study. Hum. Reprod. 2012, 27:1606-1612.
    • (2012) Hum. Reprod. , vol.27 , pp. 1606-1612
    • Rienzi, L.1
  • 47
    • 84922877271 scopus 로고    scopus 로고
    • Medical dilemma of 'three-parent babies': fertility clinic investigates health of teenagers it helped to be conceived through controversial IVF technique
    • 25 August
    • Connor S. Medical dilemma of 'three-parent babies': fertility clinic investigates health of teenagers it helped to be conceived through controversial IVF technique. Independent 2014, 25 August.
    • (2014) Independent
    • Connor, S.1
  • 48
    • 84902315464 scopus 로고    scopus 로고
    • Targeted genome editing in human repopulating haematopoietic stem cells
    • Genovese P., et al. Targeted genome editing in human repopulating haematopoietic stem cells. Nature 2014, 510:235-240.
    • (2014) Nature , vol.510 , pp. 235-240
    • Genovese, P.1
  • 49
    • 80054987997 scopus 로고    scopus 로고
    • Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells
    • Yusa K., et al. Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells. Nature 2011, 478:391-394.
    • (2011) Nature , vol.478 , pp. 391-394
    • Yusa, K.1
  • 50
    • 84903942097 scopus 로고    scopus 로고
    • Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones
    • Suzuki K., et al. Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. Cell Stem Cell 2014, 15:31-36.
    • (2014) Cell Stem Cell , vol.15 , pp. 31-36
    • Suzuki, K.1
  • 51
    • 84890033064 scopus 로고    scopus 로고
    • Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
    • Schwank G., et al. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell 2013, 13:653-658.
    • (2013) Cell Stem Cell , vol.13 , pp. 653-658
    • Schwank, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.