Three-parent in vitro fertilization: Gene replacement for the prevention of inherited mitochondrial diseases

Fertility and Sterility

Volumn 101, Issue 1, 2014, Pages 31-35

  Amato, Paula ^a   Tachibana, Masahito ^b   Sparman, Michelle ^c   Mitalipov, Shoukhrat ^c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b South Miyagi Medical Center   (Japan)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

gene replacement; Mitochondria; nuclear transfer

Indexed keywords

MITOCHONDRIAL DNA;

ARTICLE; BLASTOCYST; CELL MATURATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; FERTILIZATION IN VITRO; FOLLOW UP; GENE REPLACEMENT THERAPY; GENETIC COUNSELING; HETEROPLASMY; HUMAN; MEDICAL ETHICS; METAPHASE; OOCYTE; OOCYTE DONATION; PRIORITY JOURNAL; PROGENY; PROPHYLAXIS; STEM CELL TRANSPLANTATION; ZYGOTE; ANIMAL; CELL NUCLEUS TRANSPLANTATION; FEMALE; GENE REPLACEMENT; GENE THERAPY; GENETICS; INFERTILITY THERAPY; MALE; METHODOLOGY; MITOCHONDRION; REVIEW;

GENE REPLACEMENT; MITOCHONDRIA; NUCLEAR TRANSFER;

ANIMALS; FEMALE; FERTILIZATION IN VITRO; GENETIC THERAPY; HUMANS; MALE; MITOCHONDRIAL DISEASES; NUCLEAR TRANSFER TECHNIQUES; REPRODUCTIVE TECHNIQUES, ASSISTED;

EID: 84891541617     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.11.030     Document Type: Review

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