Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes

Cell Stem Cell

Volumn 18, Issue 6, 2016, Pages 749-754

  Yamada, Mitsutoshi ^a   Emmanuele, Valentina ^b   Sanchez Quintero, Maria J ^b   Sun, Bruce ^a   Lallos, Gregory ^a   Paull, Daniel ^a   Zimmer, Matthew ^a   Pagett, Shardonay ^a   Prosser, Robert W ^c   Sauer, Mark V ^c   Hirano, Michio ^b   Egli, Dieter ^a,b  

^a New York Stem Cell Foundation Laboratory   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA;

ARTICLE; CELL NUCLEUS TRANSPLANTATION; CONTROLLED STUDY; GENETIC DRIFT; GENOTYPE; HAPLOTYPE; HETEROPLASMY; HUMAN; HUMAN CELL; MITOCHONDRIAL GENOME; MITOCHONDRION; OOCYTE; PRIORITY JOURNAL; STEM CELL LINE; CELL LINE; CELL NUCLEUS; GENETICS; METABOLISM;

CELL LINE; CELL NUCLEUS; DNA, MITOCHONDRIAL; GENETIC DRIFT; GENOTYPE; HUMANS; MITOCHONDRIA; NUCLEAR TRANSFER TECHNIQUES; OOCYTES;

EID: 84971572010     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.04.001     Document Type: Article

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