Exo-MFA – A 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism

Metabolic Engineering

Volumn 43, Issue , 2017, Pages 156-172

  Achreja, Abhinav ^a,b,d   Zhao, Hongyun ^a,b,d   Yang, Lifeng ^a,b   Yun, Tae Hyun ^b   Marini, Juan ^c   Nagrath, Deepak ^a,b,d  

^a RICE UNIVERSITY   (United States)

^b Rice University   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

13C metabolic flux analysis; Cancer metabolism; Exo MFA; Exosomes; Intercellular metabolic flux analysis; Tumor microenvironment

Indexed keywords

AMINO ACIDS; BIOMOLECULES; CARBON; CELL CULTURE; CELLS; CYTOLOGY; DISEASES; ENZYME ACTIVITY; METABOLITES; NUCLEIC ACIDS; PATHOLOGY; PHYSIOLOGY; TUMORS;

CENTRAL CARBON METABOLISMS; COMPUTATIONAL TECHNIQUE; EXO-MFA; EXOSOMES; INTERCELLULAR COMMUNICATIONS; INTRACELLULAR METABOLISM; METABOLIC FLUX ANALYSIS; TUMOR MICROENVIRONMENT;

METABOLISM;

CARBON 13; GLUTAMINE; LACTIC ACID; CARBON;

ALGORITHM; ARTICLE; BIOGENESIS; CELL INTERACTION; CELL METABOLISM; DISSECTION; EXOSOME; GLYCOLYSIS; HUMAN; HUMAN CELL; INTERNALIZATION; METABOLIC FLUX ANALYSIS; MIA PACA-2 CELL LINE; PRIORITY JOURNAL; REGULATORY MECHANISM; TUMOR MICROENVIRONMENT; CELL COMMUNICATION; CHEMISTRY; CITRIC ACID CYCLE; ISOTOPE LABELING; METABOLISM; NEOPLASM; PATHOLOGY; SECRETION (PROCESS); TUMOR CELL LINE;

CARBON ISOTOPES; CELL COMMUNICATION; CELL LINE, TUMOR; CITRIC ACID CYCLE; EXOSOMES; GLYCOLYSIS; HUMANS; ISOTOPE LABELING; NEOPLASMS; TUMOR MICROENVIRONMENT;

EID: 85010858485     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2017.01.001     Document Type: Article

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