Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

Cell Systems

Volumn 4, Issue 1, 2017, Pages 73-83.e10

  Hill, Steven M ^a   Nesser, Nicole K ^b   Johnson Camacho, Katie ^b   Jeffress, Mara ^c   Johnson, Aimee ^d   Boniface, Chris ^b   Spencer, Simon E F ^e   Lu, Yiling ^f   Heiser, Laura M ^g   Lawrence, Yancey ^b   Pande, Nupur T ^b,h   Korkola, James E ^g   Gray, Joe W ^b,g   Mills, Gordon B ^f   Mukherjee, Sach ^a,i   Spellman, Paul T ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c KANTAR HEALTH   (United States)

^d BAYER CORPORATION   (United States)

^e UNIVERSITY OF WARWICK   (United Kingdom)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g Oregon Health and Science University Department of Biomedical Engineering   (United States)

^h OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

ⁱ GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

breast cancer cell lines; casual networks; computational systems biology; context specific networks; data resource; empirical assessment; network inference; protein signaling networks; reverse phase protein array data

Indexed keywords

5 (3 FLUOROPHENYL) N (3 PIPERIDINYL) 3 UREIDO 2 THIOPHENECARBOXAMIDE; AZD 8055; DACTOLISIB; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; PHOSPHOPROTEIN; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE B; SCATTER FACTOR; TRANSCRIPTION FACTOR RELA;

ARTICLE; BREAST CANCER CELL LINE; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; HUMAN; HUMAN CELL; NETWORK LEARNING; PRIORITY JOURNAL; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ALGORITHM; BIOLOGICAL MODEL; BIOLOGY; BREAST TUMOR; COMPUTER SIMULATION; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ALGORITHMS; BREAST NEOPLASMS; CELL LINE, TUMOR; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; MODELS, BIOLOGICAL; PHOSPHOPROTEINS; PHOSPHORYLATION; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 85010685970     PISSN: 24054712     EISSN: 24054720     Source Type: Journal    
DOI: 10.1016/j.cels.2016.11.013     Document Type: Article

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