Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases

Nature Methods

Volumn 13, Issue 4, 2016, Pages 366-370

  Marbach, Daniel ^a,b   Lamparter, David ^a,b   Quon, Gerald ^c,d   Kellis, Manolis ^c,d   Kutalik, Zoltán ^b,e   Bergmann, Sven ^a,b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ARTICLE; CELLS BY BODY ANATOMY; ENHANCER REGION; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; GENETIC ASSOCIATION STUDY; GENETIC VARIABILITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE TRAIT LOCUS; TISSUE SPECIFICITY; ANTIBODY SPECIFICITY; BIOLOGY; BRAIN DISEASE; CELL LINEAGE; EPIGENETICS; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN GENOME; METABOLISM; PROCEDURES; PROTEIN ANALYSIS;

BRAIN DISEASES; CELL LINEAGE; COMPUTATIONAL BIOLOGY; EPIGENOMICS; GENE REGULATORY NETWORKS; GENETIC VARIATION; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; PROTEIN INTERACTION MAPPING; TRANSCRIPTION FACTORS;

EID: 84960145592     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.3799     Document Type: Article

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