Age-dependent concomitant changes in synaptic function and GABAergic pathway in the APP/PS1 mouse model

Acta Neurobiologiae Experimentalis

Volumn 76, Issue 4, 2016, Pages 282-293

  Oyelami, Tutu ^a,c   De Bondt, An ^a   Van den Wyngaert, Ilse ^a   Van Hoorde, Kirsten ^b   Hoskens, Luc ^a   Shaban, Hamdy ^a   Kemp, John A ^a   Drinkenburg, Wilhelmus H ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b Open Analytics   (Belgium)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Alzheimer s disease; APP PS1; Expression profile; GABAergic; Glutamatergic; Long term potentiation; Seizures

Indexed keywords

4 AMINOBUTYRIC ACID; AMYLOID PRECURSOR PROTEIN; GABAERGIC RECEPTOR AFFECTING AGENT; PRESENILIN 1; PSEN1 PROTEIN, HUMAN;

AGING; ALZHEIMER DISEASE; ANIMAL; C57BL MOUSE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ELECTROSTIMULATION; GENETICS; HIPPOCAMPUS; HUMAN; IN VITRO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYNAPSE; TRANSGENIC MOUSE;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; GABA AGENTS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; HUMANS; IN VITRO TECHNIQUES; INHIBITORY POSTSYNAPTIC POTENTIALS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PRESENILIN-1; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 85010501232     PISSN: 00651400     EISSN: 16890035     Source Type: Journal    
DOI: 10.21307/ane-2017-027     Document Type: Article

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