RIP1 and RIP3 contribute to shikonin-induced DNA double-strand breaks in glioma cells via increase of intracellular reactive oxygen species

Cancer Letters

Volumn 390, Issue , 2017, Pages 77-90

  Zhou, Zijian ^a   Lu, Bin ^a   Wang, Chen ^a   Wang, Zongqi ^a   Luo, Tianfei ^a   Piao, Meihua ^a   Meng, Fankai ^b   Chi, Guangfan ^c   Luo, Yinan ^a   Ge, Pengfei ^a  

^a THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^b Jilin Province People's Hospital   (China)

^c JILIN UNIVERSITY   (China)

Author keywords

DNA double strand breaks; Glioma cell; RIP1 and RIP3; ROS; Shikonin

Indexed keywords

HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RECEPTOR INTERACTING SERINE THREONINE PROTEIN KINASE 1; RECEPTOR INTERACTING SERINE THREONINE PROTEIN KINASE 3; SHIKONIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; AGFG1 PROTEIN, HUMAN; NAPHTHOQUINONE; NUCLEOPORIN; RIPK3 PROTEIN, HUMAN; RNA BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; GENE SILENCING; GLIOMA; GLIOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; RAT; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; DNA BREAKS, DOUBLE-STRANDED; GLIOMA; HETEROGRAFTS; MICE; NAPHTHOQUINONES; NUCLEAR PORE COMPLEX PROTEINS; REACTIVE OXYGEN SPECIES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RNA-BINDING PROTEINS; UP-REGULATION;

EID: 85010470377     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2017.01.004     Document Type: Article

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