An oxidative stress mechanism of shikonin in human glioma cells

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Yang, Jen Tsung ^a,b   Li, Zih Ling ^a,b,c   Wu, Jin Yi ^c   Lu, Fung Jou ^d   Chen, Ching Hsein ^c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; LIPOXYGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SHIKONIN; SUPEROXIDE; TRANSCRIPTION FACTOR NRF2; UBIQUINOL CYTOCHROME C REDUCTASE; ANTINEOPLASTIC AGENT; NAPHTHOQUINONE; NFE2L2 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER GRADING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG PENETRATION; GLIOMA CELL; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; CELL CYCLE; CYTOSOL; DRUG EFFECTS; GENETICS; GLIOMA; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CYTOCHROMES C; CYTOSOL; GLIOMA; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NAPHTHOQUINONES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 84899450042     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094180     Document Type: Article

References (29)

1. Chen CH, Lin ML, Ong PL, Yang JT (2012) Novel multiple apoptotic mechanism of shikonin in human glioma cells. Ann Surg Oncol;19: 3097-3106.
2. Chen CH, Chern CL, Lin CC, Lu FJ, Shih MK, et al. (2003) Involvement of reactive oxygen species, but not mitochondrial permeability transition in the apoptotic induction of human SK-Hep-1 hepatoma cells by shikonin. Planta Med; 69: 1119-1124.
3. Ray PD, Huang BW, Tsuji Y (2012) Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell Signal; 24: 981-990.
4. Aldaba-Muruato LR, Moreno MG, Hernández-Mercado E, Shibayama M, Muriel P (2012) Secondary biliary cirrhosis in the rat is prevented by decreasing NF-κB nuclear translocation and TGF- expression using allopurinol, an inhibitor of xanthine oxidase. Can J Physiol Pharmacol; 90: 1469-1478.
5. Lee HN, Surh YJ (2013) Resolvin D1-mediated NOX2 inactivation rescues macrophages undertaking efferocytosis from oxidative stress-induced apoptosis. Biochem Pharmacol; 86: 759-769.
6. Jabůrek M, Ježek J, Zelenka J, Ježek P (2013) Antioxidant activity by a synergy of redox-sensitive mitochondrial phospholipase A2 and uncoupling protein-2 in lung and spleen. Int J Biochem Cell Biol; 45: 816-825.
7. Bobba A, Amadoro G, Valenti D, Corsetti V, Lassandro R, et al. (2013) Mitochondrial respiratory chain Complexes I and IV are impaired by β-amyloid via direct interaction and through Complex I-dependent ROS production, respectively. Mitochondrion; 13: 298-311.
8. García-Escudero V, Martín-Maestro P, Perry G, Avila J (2013) Deconstructing Mitochondrial Dysfunction in Alzheimer Disease. Oxid Med Cell Longev; 2013: 162152.
9. Garcia-Perez C, Roy SS, Naghdi S, Lin X, Davies E, et al. (2012) Bid-induced mitochondrial membrane permeabilization waves propagated by local reactive oxygen species (ROS) signaling. Proc Natl Acad Sci U S A; 109: 4497-4502.
10. Rincheval V, Bergeaud M, Mathieu L, Leroy J, Guillaume A, Mignotte B, et al. (2012) Differential effects of Bcl-2 and caspases on mitochondrial permeabilization during endogenous or exogenous reactive oxygen species-induced cell death. Cell Biol Toxicol; 28: 239-253.
11. Gao S, Chen T, Choi MY, Liang Y, Xue J, et al. (2013) Cyanidin reverses cisplatin-induced apoptosis in HK-2 proximal tubular cells through inhibition of ROS-mediated DNA damage and modulation of the ERK and AKT pathways. Cancer Lett; 333: 36-46.
12. Pal HC, Sharma S, Elmets CA, Athar M, Afaq F (2013) Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: role of mitochondrial membrane potential disruption and consequent caspases activation. Exp Dermatol; 22: 470-475.
13. Conklin KA (2004) Cancer chemotherapy and anti-oxidants. J Nutr; 134: 3201-3204.
14. Klaus V, Hartmann T, Gambini J, Graf P, Stahl W, et al. (2010) 1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes. Arch Biochem Biophys; 496: 93-100.
15. Kim HJ, Mun JY, Chun YJ, Choi KH, Ham SW, et al. (2003) Effects of a naphthoquinone analog on tumor growth and apoptosis induction. Arch Pharm Res; 26: 405-410.
16. Wu FY, Chang NT, Chen WJ, Juan CC (1993) Vitamin K3-induced cell cycle arrest and apoptotic cell death are accompanied by altered expression of c-fos and c-myc in nasopharyngeal carcinoma cells. Oncogene; 8: 2237-2244.
17. Okayasu H, Ishihara M, Satoh K, Sakagami H (2001) Cytotoxic activity of vitamins K1, K2 and K3 against human oral tumor cell lines. Anticancer Res; 21: 2387-2392.
18. Miller MG, Rodgers A, Cohen GM (1986) Mechanisms of toxicity of naphthoquinones to isolated hepatocytes. Biochem Pharmacol; 35: 1177-1184.
19. Waris G, Ahsan H (2006) Reactive oxygen species: role in the development of cancer and various chronic conditions. J Carcinog; 5: 14.
20. Xu KH, Lu DP (2010) Plumbagin induces ROS-mediated apoptosis in human promyelocytic leukemia cells in vivo. Leuk Res; 34: 658-665.
21. Ozben T (2007) Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci; 96: 2181-2196.
22. Schumacker PT (2006) Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell; 10: 175-176.
23. Kuo HM, Chang LS, Lin YL, Lu HF, Yang JS, et al. (2007) Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway. Anticancer Res; 27: 395-405.
24. Byun JY, Kim MJ, Eum DY, Yoon CH, Seo WD, et al. (2009) Reactive oxygen species-dependent activation of Bax and poly(ADP-ribose) polymerase-1 is required for mitochondrial cell death induced by triterpenoid pristimerin in human cervical cancer cells. Mol Pharmacol; 76: 734-744.
25. Ralph SJ, Moreno-Sánchez R, Neuzil J, Rodríguez- Enríquez S (2011) Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygenspecies and protect normal cells from ischemic damage but induce specific cancer cell death. Pharm Res; 28: 2695-2730.
26. James AM, Sharpley MS, Manas AR, Frerman FE, Hirst J, et al. (2007) Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers andubiquinone oxidoreductases. J Biol Chem; 282: 14708-14718.
27. Nguyen MV, Lardy B, Rousset F, Hazane-Puch F, Zhang L, et al. (2013) Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4. Biochem Pharmacol; 85: 1644-1654.
28. Paletta-Silva R, Rocco-Machado N, Meyer-Fernandes JR (2013) NADPH oxidase biology and the regulation of tyrosine kinase receptor signaling and cancer drug cytotoxicity. Int J Mol Sci; 14: 3683-3704.
29. Schramm A, Matusik P, Osmenda G, Guzik TJ (2012) Targeting NADPH oxidases in vascular pharmacology. Vascul Pharmacol; 56: 216-231.