Altered stoichiometry Escherichia coli Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation

Nucleic Acids Research

Volumn 44, Issue 22, 2016, Pages 10849-10861

  Kuznedelov, Konstantin ^a   Mekler, Vladimir ^a   Lemak, Sofia ^b   Tokmina Lukaszewska, Monika ^c   Datsenko, Kirill A ^d   Jain, Ishita ^a   Savitskaya, Ekaterina ^e,f   Mallon, John ^g   Shmakov, Sergey ^e,h   Bothner, Brian ^c   Bailey, Scott ^g   Yakunin, Alexander F ^b   Severinov, Konstantin ^a,e,f,i   Semenova, Ekaterina ^a  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c MONTANA STATE UNIVERSITY   (United States)

^d PURDUE UNIVERSITY   (United States)

^e SKOLKOVO INSTITUTE OF SCIENCE AND TECHNOLOGY   (Russian Federation)

^f INSTITUTE OF MOLECULAR GENETICS   (Russian Federation)

^g JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^h NATIONAL INSTITUTES OF HEALTH   (United States)

ⁱ PETER THE GREAT ST PETERSBURG POLYTECHNIC UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR RNA; RNA; UNCLASSIFIED DRUG; BACTERIAL RNA;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CRISPR CAS SYSTEM; ESCHERICHIA COLI; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; RNA PURIFICATION; STOICHIOMETRY; ADAPTATION; BASE PAIRING; BINDING SITE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; RNA INTERFERENCE;

ADAPTATION, PHYSIOLOGICAL; BASE PAIRING; BASE SEQUENCE; BINDING SITES; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; RNA INTERFERENCE; RNA, BACTERIAL;

EID: 85010412028     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw914     Document Type: Article

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