Selenomethionine promoted hippocampal neurogenesis via the PI3K-Akt-GSK3β-Wnt pathway in a mouse model of Alzheimer's disease

Biochemical and Biophysical Research Communications

Volumn 485, Issue 1, 2017, Pages 6-15

  Zheng, Rui ^a   Zhang, Zhong Hao ^a   Chen, Chen ^a   Chen, Yao ^a   Jia, Shi Zheng ^a   Liu, Qiong ^a   Ni, Jia Zuan ^a   Song, Guo Li ^a  

^a SHENZHEN UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Neurogenesis; Selenomethionine; Wnt pathway

Indexed keywords

BETA CATENIN; BROXURIDINE; CYCLIN D; DOUBLECORTIN; GLYCOGEN SYNTHASE KINASE 3; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SELENOMETHIONINE; GLYCOGEN SYNTHASE KINASE 3BETA;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ASTROCYTE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; HIPPOCAMPUS; IN VITRO STUDY; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; STEM CELL SELF-RENEWAL; WESTERN BLOTTING; WNT SIGNALING PATHWAY; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; WNT SIGNALING;

ALZHEIMER DISEASE; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; GLYCOGEN SYNTHASE KINASE 3 BETA; HIPPOCAMPUS; MALE; MICE; MICE, TRANSGENIC; NEURAL STEM CELLS; NEUROGENESIS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SELENOMETHIONINE; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY;

EID: 85009985679     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.01.069     Document Type: Review

References (55)

1. [1] Heberden, C., Modulating adult neurogenesis through dietary interventions. Nutr. Res. Rev., 2016, 1–9.
2. [2] Xu, W.S., et al. Bumetanide promotes neural precursor cell regeneration and dendritic development in the hippocampal dentate gyrus in the chronic stage of cerebral ischemia. Neural Regen. Res. 11:5 (2016), 745–751.
3. [3] Kumar, V., et al. Differential responses of Trans-Resveratrol on proliferation of neural progenitor cells and aged rat hippocampal neurogenesis. Sci. Rep., 6, 2016, 28142.
4. [4] Zhao, C., Deng, W., Gage, F.H., Mechanisms and functional implications of adult neurogenesis. Cell 132:4 (2008), 645–660.
5. [5] Sury, M.D., et al. JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiol. Dis. 32:1 (2008), 142–150.
6. [6] Deng, W., Aimone, J.B., Gage, F.H., New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?. Nat. Rev. Neurosci. 11:5 (2010), 339–350.
7. [7] Huang, Y., Mucke, L., Alzheimer mechanisms and therapeutic strategies. Cell 148:6 (2012), 1204–1222.
8. [8] van Praag, H., et al. Functional neurogenesis in the adult hippocampus. Nature 415:6875 (2002), 1030–1034.
9. [9] Vadodaria, K.C., Jessberger, S., Functional neurogenesis in the adult hippocampus: then and now. Front. Neurosci., 8, 2014, 55.
10. [10] Hu, Y., Zhu, D.Y., Hippocampus and nitric oxide. Vitam. Horm. 96 (2014), 127–160.
11. [11] Kim, H.J., et al. Effects of gintonin-enriched fraction on hippocampal cell proliferation in wild-type mice and an APPswe/PSEN-1 double Tg mouse model of Alzheimer's disease. Neurochem. Int. 101 (2016), 56–65.
12. [12] Kim, D.Y., et al. Treadmill exercise ameliorates Alzheimer disease-associated memory loss through the Wnt signaling pathway in the streptozotocin-induced diabetic rats. J. Exerc Rehabil. 12:4 (2016), 276–283.
13. [13] Lavu, R.V., et al. Selenium bioaccessibility in stomach, small intestine and colon: comparison between pure Se compounds, Se-enriched food crops and food supplements. Food Chem. 197:Pt A (2016), 382–387.
14. [14] Burk, R.F., et al. Selenium deficiency occurs in some patients with moderate-to-severe cirrhosis and can be corrected by administration of selenate but not selenomethionine: a randomized controlled trial. Am. J. Clin. Nutr. 102:5 (2015), 1126–1133.
15. [15] Zhang, Z.H., et al. Selenomethionine reduces the deposition of beta-amyloid plaques by modulating beta-secretase and enhancing selenoenzymatic activity in a mouse model of Alzheimer's disease. Metallomics 8:8 (2016), 782–789.
16. [16] Oddo, S., et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39:3 (2003), 409–421.
17. [17] Song, G., et al. Selenomethionine ameliorates cognitive decline, reduces tau hyperphosphorylation, and reverses synaptic deficit in the triple transgenic mouse model of Alzheimer's disease. J. Alzheimers Dis. 41:1 (2014), 85–99.
18. [18] Xiong, S., et al. Seleno-L-methionine protects against beta-amyloid and iron/hydrogen peroxide-mediated neuron death. Antioxid. Redox Signal 9:4 (2007), 457–467.
19. [19] Hameed, L.A., Simon, A., Isolation and culture of neurospheres from the adult newt brain. Methods Mol. Biol. 1290 (2015), 197–204.
20. [20] Nosrati, A., et al. Cancer stem cells CD133 and CD24 in colorectal cancers in Northern Iran. Gastroenterol. Hepatol. Bed Bench 9:2 (2016), 132–139.
21. [21] Chen, J., et al. PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells. Clin. Exp. Pharmacol. Physiol. 42:12 (2015), 1317–1326.
22. [22] Park, D., et al. Nestin is required for the proper self-renewal of neural stem cells. Stem Cells 28:12 (2010), 2162–2171.
23. [23] Witusik, M., et al. Successful elimination of non-neural cells and unachievable elimination of glial cells by means of commonly used cell culture manipulations during differentiation of GFAP and SOX2 positive neural progenitors (NHA) to neuronal cells. BMC Biotechnol., 8, 2008, 56.
24. [24] Tiwari, S.K., et al. Ethosuximide induces hippocampal neurogenesis and reverses cognitive deficits in an amyloid-beta toxin-induced Alzheimer rat model via the phosphatidylinositol 3-kinase (PI3K)/Akt/Wnt/beta-Catenin pathway. J. Biol. Chem. 290:47 (2015), 28540–28558.
25. [25] Andreu-Agullo, C., et al. Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone. Nat. Neurosci. 12:12 (2009), 1514–1523.
26. [26] Hollands, C., Bartolotti, N., Lazarov, O., Alzheimer's disease and hippocampal adult neurogenesis; exploring shared mechanisms. Front. Neurosci., 10, 2016, 178.
27. [27] Zheng, M., et al. Intrahippocampal injection of Abeta1-42 inhibits neurogenesis and down-regulates IFN-gamma and NF-kappaB expression in hippocampus of adult mouse brain. Amyloid 20:1 (2013), 13–20.
28. [28] Lie, D.C., et al. Wnt signalling regulates adult hippocampal neurogenesis. Nature 437:7063 (2005), 1370–1375.
29. [29] Kuwabara, T., et al. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nat. Neurosci. 12:9 (2009), 1097–1105.
30. [30] Zhou, F.Q., Snider, W.D., Cell biology. GSK-3beta and microtubule assembly in axons. Science 308:5719 (2005), 211–214.
31. [31] Dong, C., Rovnaghi, C.R., Anand, K.J., Ketamine affects the neurogenesis of rat fetal neural stem progenitor cells via the PI3K/Akt-p27 signaling pathway. Birth Defects Res. B Dev. Reprod. Toxicol. 101:5 (2014), 355–363.
32. [32] Bruel-Jungerman, E., et al. Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus. PLoS One, 4(11), 2009, e7901.
33. [33] Ortiz-Matamoros, A., et al. Role of wnt signaling in the control of adult hippocampal functioning in health and disease: therapeutic implications. Curr. Neuropharmacol. 11:5 (2013), 465–476.
34. [34] Ming, G.L., Song, H., Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neurosci. 28 (2005), 223–250.
35. [35] Crews, L., et al. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J. Neurosci. 30:37 (2010), 12252–12262.
36. [36] Lie, D.C., et al. Neurogenesis in the adult brain: new strategies for central nervous system diseases. Annu. Rev. Pharmacol. Toxicol. 44 (2004), 399–421.
37. [37] Tatebayashi, Y., et al. The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta Neuropathol. 105:3 (2003), 225–232.
38. [38] Jin, K., et al. Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum. Mol. Cell Neurosci. 24:1 (2003), 171–189.
39. [39] Armstrong, R.J., Barker, R.A., Neurodegeneration: a failure of neuroregeneration?. Lancet 358:9288 (2001), 1174–1176.
40. [40] Rodriguez, J.J., Verkhratsky, A., Neurogenesis in Alzheimer's disease. J. Anat. 219:1 (2011), 78–89.
41. [41] Rodriguez, J.J., et al. Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. PLoS One, 3(8), 2008, e2935.
42. [42] Yeo, J.E., Kang, S.K., Selenium effectively inhibits ROS-mediated apoptotic neural precursor cell death in vitro and in vivo in traumatic brain injury. Biochim. Biophys. Acta 1772:11–12 (2007), 1199–1210.
43. [43] Nishina, A., et al. Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase. J. Neurosci. Res. 86:3 (2008), 720–725.
44. [44] Nishina, A., et al. Selenazoles (selenium compounds) facilitate survival of cultured rat pheochromocytoma PC12 cells after serum-deprivation and stimulate their neuronal differentiation via activation of Akt and mitogen-activated protein kinase, respectively. Biochem. Biophys. Res. Commun. 352:2 (2007), 360–365.
45. [45] Liu, Y., et al. Endogenous neural stem cells in central canal of adult rats acquired limited ability to differentiate into neurons following mild spinal cord injury. Int. J. Clin. Exp. Pathol. 8:4 (2015), 3835–3842.
46. [46] Liu, Y., et al. The effects of different phenotype astrocytes on neural stem cells differentiation in co-culture. Neurosci. Lett. 508:2 (2012), 61–66.
47. [47] Jang, S., et al. Blunted response of hippocampal AMPK associated with reduced neurogenesis in older versus younger mice. Prog. Neuropsychopharmacol. Biol. Psychiatry 71 (2016), 57–65.
48. [48] Kwan, H.T., et al. AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/beta-catenin signaling activity. PLoS One, 8(1), 2013, e53597.
49. [49] Liu, J.D., et al. Wnt/glycogen synthase kinase 3beta/beta-catenin signaling activation mediated sevoflurane preconditioning-induced cardioprotection. Chin. Med. J. Engl. 128:17 (2015), 2346–2353.
50. [50] Shimizu, T., et al. Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells. Mol. Cell Biol. 28:24 (2008), 7427–7441.
51. [51] Inestrosa, N.C., Arenas, E., Emerging roles of Wnts in the adult nervous system. Nat. Rev. Neurosci. 11:2 (2010), 77–86.
52. [52] Kalani, M.Y., et al. Wnt-mediated self-renewal of neural stem/progenitor cells. Proc. Natl. Acad. Sci. U. S. A. 105:44 (2008), 16970–16975.
53. [53] Kaur, N., et al. Wnt3a mediated activation of Wnt/beta-catenin signaling promotes tumor progression in glioblastoma. Mol. Cell Neurosci. 54 (2013), 44–57.
54. [54] Mendelev, N., et al. Selenite stimulates mitochondrial biogenesis signaling and enhances mitochondrial functional performance in murine hippocampal neuronal cells. PLoS One, 7(10), 2012, e47910.
55. [55] Kitagishi, Y., et al. Roles of PI3K/AKT/GSK3/mTOR pathway in cell signaling of mental illnesses. Depress Res. Treat., 2012, 2012, 752563.