Ketamine affects the neurogenesis of rat fetal neural stem progenitor cells via the PI3K/Akt-p27 signaling pathway

Birth defects research. Part B, Developmental and reproductive toxicology

Volumn 101, Issue 5, 2014, Pages 355-363

  Dong, Chaoxuan ^a   Rovnaghi, Cynthia R ^a   Anand, Kanwaljeet J S ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

embryogenesis; embryonic fetal physiology; pharmaceuticals; safety assessment; signal transduction

Indexed keywords

ANALGESIC AGENT; CDKN1B PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1B; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

AGONISTS; ANIMAL; BRAIN; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; EMBRYOLOGY; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANALGESICS; ANIMALS; BRAIN; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; KETAMINE; MAP KINASE SIGNALING SYSTEM; N-METHYLASPARTATE; NEURAL STEM CELLS; NEUROGENESIS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 85027936563     PISSN: None     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.21119     Document Type: Article

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