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Volumn 16, Issue , 2017, Pages 63-75

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF

Author keywords

BRN2; Epigenetic; Invasion; Melanoma; Metastasis; NFIB

Indexed keywords

DOXYCYCLINE; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EZH2; EZH2 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; MITF PROTEIN, HUMAN; NFIB PROTEIN, HUMAN; NUCLEAR FACTOR I; PROTEIN BINDING; TRANSCRIPTION FACTOR BRN-2; TRANSCRIPTION FACTOR POU;

EID: 85009985653     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2017.01.013     Document Type: Article
Times cited : (70)

References (53)
  • 2
    • 33644822360 scopus 로고    scopus 로고
    • EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
    • Bachmann, I.M., Halvorsen, O.J., Collett, K., Stefansson, I.M., Straume, O., Haukaas, S.A., Salvesen, H.B., Otte, A.P., Akslen, L.A., EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J. Clin. Oncol. 24 (2006), 268–273.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 268-273
    • Bachmann, I.M.1    Halvorsen, O.J.2    Collett, K.3    Stefansson, I.M.4    Straume, O.5    Haukaas, S.A.6    Salvesen, H.B.7    Otte, A.P.8    Akslen, L.A.9
  • 4
    • 84952845574 scopus 로고    scopus 로고
    • Imaging- and flow cytometry-based analysis of cell position and the cell cycle in 3D melanoma spheroids
    • Beaumont, K.A., Anfosso, A., Ahmed, F., Weninger, W., Haass, N.K., Imaging- and flow cytometry-based analysis of cell position and the cell cycle in 3D melanoma spheroids. J. Vis. Exp., 106, 2015, e53486.
    • (2015) J. Vis. Exp. , vol.106
    • Beaumont, K.A.1    Anfosso, A.2    Ahmed, F.3    Weninger, W.4    Haass, N.K.5
  • 10
    • 56249083567 scopus 로고    scopus 로고
    • POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis
    • Cook, A.L., Sturm, R.A., POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis. Pigment Cell Melanoma Res. 21 (2008), 611–626.
    • (2008) Pigment Cell Melanoma Res. , vol.21 , pp. 611-626
    • Cook, A.L.1    Sturm, R.A.2
  • 11
    • 0242490087 scopus 로고    scopus 로고
    • Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3
    • Cook, A.L., Donatien, P.D., Smith, A.G., Murphy, M., Jones, M.K., Herlyn, M., Bennett, D.C., Leonard, J.H., Sturm, R.A., Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3. J. Invest. Dermatol. 121 (2003), 1150–1159.
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 1150-1159
    • Cook, A.L.1    Donatien, P.D.2    Smith, A.G.3    Murphy, M.4    Jones, M.K.5    Herlyn, M.6    Bennett, D.C.7    Leonard, J.H.8    Sturm, R.A.9
  • 12
    • 22144462047 scopus 로고    scopus 로고
    • Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro
    • Cook, A.L., Smith, A.G., Smit, D.J., Leonard, J.H., Sturm, R.A., Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro. Exp. Cell Res. 308 (2005), 222–235.
    • (2005) Exp. Cell Res. , vol.308 , pp. 222-235
    • Cook, A.L.1    Smith, A.G.2    Smit, D.J.3    Leonard, J.H.4    Sturm, R.A.5
  • 15
    • 79954471872 scopus 로고    scopus 로고
    • EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression
    • Fan, T., Jiang, S.L., Chung, N., Alikhan, A., Ni, C., Lee, C.C.R., Hornyak, T.J., EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression. Mol. Cancer Res. 9 (2011), 418–429.
    • (2011) Mol. Cancer Res. , vol.9 , pp. 418-429
    • Fan, T.1    Jiang, S.L.2    Chung, N.3    Alikhan, A.4    Ni, C.5    Lee, C.C.R.6    Hornyak, T.J.7
  • 17
    • 84898645670 scopus 로고    scopus 로고
    • Dedifferentiation and reprogramming: origins of cancer stem cells
    • Friedmann-Morvinski, D., Verma, I.M., Dedifferentiation and reprogramming: origins of cancer stem cells. EMBO Rep. 15 (2014), 244–253.
    • (2014) EMBO Rep. , vol.15 , pp. 244-253
    • Friedmann-Morvinski, D.1    Verma, I.M.2
  • 18
    • 79956076149 scopus 로고    scopus 로고
    • Commentary. A picture of Mitf in melanoma immortality
    • Goding, C.R., Commentary. A picture of Mitf in melanoma immortality. Oncogene 30 (2011), 2304–2306.
    • (2011) Oncogene , vol.30 , pp. 2304-2306
    • Goding, C.R.1
  • 19
    • 54249164136 scopus 로고    scopus 로고
    • Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells
    • Goodall, J., Carreira, S., Denat, L., Kobi, D., Davidson, I., Nuciforo, P., Sturm, R.A., Larue, L., Goding, C.R., Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells. Cancer Res. 68 (2008), 7788–7794.
    • (2008) Cancer Res. , vol.68 , pp. 7788-7794
    • Goodall, J.1    Carreira, S.2    Denat, L.3    Kobi, D.4    Davidson, I.5    Nuciforo, P.6    Sturm, R.A.7    Larue, L.8    Goding, C.R.9
  • 22
    • 84924046828 scopus 로고    scopus 로고
    • Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations
    • Harris, L., Genovesi, L.A., Gronostajski, R.M., Wainwright, B.J., Piper, M., Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations. Dev. Dyn. 244 (2015), 227–238.
    • (2015) Dev. Dyn. , vol.244 , pp. 227-238
    • Harris, L.1    Genovesi, L.A.2    Gronostajski, R.M.3    Wainwright, B.J.4    Piper, M.5
  • 23
    • 84929365675 scopus 로고    scopus 로고
    • MITF in melanoma: mechanisms behind its expression and activity
    • Hartman, M.L., Czyz, M., MITF in melanoma: mechanisms behind its expression and activity. Cell. Mol. Life Sci. 72 (2015), 1249–1260.
    • (2015) Cell. Mol. Life Sci. , vol.72 , pp. 1249-1260
    • Hartman, M.L.1    Czyz, M.2
  • 24
    • 78049237405 scopus 로고    scopus 로고
    • Cancer stem cells versus phenotype-switching in melanoma
    • Hoek, K.S., Goding, C.R., Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell Melanoma Res. 23 (2010), 746–759.
    • (2010) Pigment Cell Melanoma Res. , vol.23 , pp. 746-759
    • Hoek, K.S.1    Goding, C.R.2
  • 26
    • 79955962275 scopus 로고    scopus 로고
    • Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation
    • Hsu, Y.C., Osinski, J., Campbell, C.E., Litwack, E.D., Wang, D., Liu, S., Bachurski, C.J., Gronostajski, R.M., Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation. Dev. Biol. 354 (2011), 242–252.
    • (2011) Dev. Biol. , vol.354 , pp. 242-252
    • Hsu, Y.C.1    Osinski, J.2    Campbell, C.E.3    Litwack, E.D.4    Wang, D.5    Liu, S.6    Bachurski, C.J.7    Gronostajski, R.M.8
  • 27
    • 77952560302 scopus 로고    scopus 로고
    • Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene
    • Kobi, D., Steunou, A.L., Dembele, D., Legras, S., Larue, L., Nieto, L., Davidson, I., Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene. Pigment Cell Melanoma Res. 23 (2010), 404–418.
    • (2010) Pigment Cell Melanoma Res. , vol.23 , pp. 404-418
    • Kobi, D.1    Steunou, A.L.2    Dembele, D.3    Legras, S.4    Larue, L.5    Nieto, L.6    Davidson, I.7
  • 28
    • 33747882661 scopus 로고    scopus 로고
    • MITF: master regulator of melanocyte development and melanoma oncogene
    • Levy, C., Khaled, M., Fisher, D.E., MITF: master regulator of melanocyte development and melanoma oncogene. Trends Mol. Med. 12 (2006), 406–414.
    • (2006) Trends Mol. Med. , vol.12 , pp. 406-414
    • Levy, C.1    Khaled, M.2    Fisher, D.E.3
  • 30
    • 84939565728 scopus 로고    scopus 로고
    • Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells
    • Manning, C.S., Hooper, S., Sahai, E.A., Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells. Oncogene 34 (2015), 4320–4332.
    • (2015) Oncogene , vol.34 , pp. 4320-4332
    • Manning, C.S.1    Hooper, S.2    Sahai, E.A.3
  • 31
    • 84860214990 scopus 로고    scopus 로고
    • Intra-tumour heterogeneity: a looking glass for cancer?
    • Marusyk, A., Almendro, V., Polyak, K., Intra-tumour heterogeneity: a looking glass for cancer?. Nat. Rev. Cancer 12 (2012), 323–334.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 323-334
    • Marusyk, A.1    Almendro, V.2    Polyak, K.3
  • 33
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell, P.C., The clonal evolution of tumor cell populations. Science 194 (1976), 23–28.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 34
    • 73249115584 scopus 로고    scopus 로고
    • Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck
    • Persson, M., Andren, Y., Mark, J., Horlings, H.M., Persson, F., Stenman, G., Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 18740–18744.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 18740-18744
    • Persson, M.1    Andren, Y.2    Mark, J.3    Horlings, H.M.4    Persson, F.5    Stenman, G.6
  • 35
    • 70350214467 scopus 로고    scopus 로고
    • Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination
    • Pinner, S., Jordan, P., Sharrock, K., Bazley, L., Collinson, L., Marais, R., Bonvin, E., Goding, C., Sahai, E., Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination. Cancer Res. 69 (2009), 7969–7977.
    • (2009) Cancer Res. , vol.69 , pp. 7969-7977
    • Pinner, S.1    Jordan, P.2    Sharrock, K.3    Bazley, L.4    Collinson, L.5    Marais, R.6    Bonvin, E.7    Goding, C.8    Sahai, E.9
  • 38
    • 78249250559 scopus 로고    scopus 로고
    • Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized
    • Quintana, E., Shackleton, M., Foster, H.R., Fullen, D.R., Sabel, M.S., Johnson, T.M., Morrison, S.J., Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 18 (2010), 510–523.
    • (2010) Cancer Cell , vol.18 , pp. 510-523
    • Quintana, E.1    Shackleton, M.2    Foster, H.R.3    Fullen, D.R.4    Sabel, M.S.5    Johnson, T.M.6    Morrison, S.J.7
  • 39
  • 42
    • 0027892512 scopus 로고
    • Cellular-origin of cancer — dedifferentiation or stem-cell maturation arrest
    • Sell, S., Cellular-origin of cancer — dedifferentiation or stem-cell maturation arrest. Environ. Health Perspect. 101 (1993), 15–26.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 15-26
    • Sell, S.1
  • 44
    • 38849182724 scopus 로고    scopus 로고
    • In vitro three-dimensional tumor microenvironment models for anticancer drug discovery
    • Smalley, K.S., Lioni, M., Noma, K., Haass, N.K., Herlyn, M., In vitro three-dimensional tumor microenvironment models for anticancer drug discovery. Expert Opin. Drug Discovery 3 (2008), 1–10.
    • (2008) Expert Opin. Drug Discovery , vol.3 , pp. 1-10
    • Smalley, K.S.1    Lioni, M.2    Noma, K.3    Haass, N.K.4    Herlyn, M.5
  • 45
    • 85014108851 scopus 로고    scopus 로고
    • Real-time cell cycle imaging in a 3D cell culture model of melanoma
    • (in press)
    • Spoerri, L., Beaumont, K.A., Anfosso, A., Haass, N.K., Real-time cell cycle imaging in a 3D cell culture model of melanoma. Methods Mol. Biol., 2017 (in press).
    • (2017) Methods Mol. Biol.
    • Spoerri, L.1    Beaumont, K.A.2    Anfosso, A.3    Haass, N.K.4
  • 48
    • 84915819303 scopus 로고    scopus 로고
    • Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity
    • Vandamme, N., Berx, G., Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity. Front. Oncol., 4, 2014, 352.
    • (2014) Front. Oncol. , vol.4 , pp. 352
    • Vandamme, N.1    Berx, G.2
  • 50
    • 84930925982 scopus 로고    scopus 로고
    • Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy
    • Wellbrock, C., Arozarena, I., Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy. Pigment Cell Melanoma Res. 28 (2015), 390–406.
    • (2015) Pigment Cell Melanoma Res. , vol.28 , pp. 390-406
    • Wellbrock, C.1    Arozarena, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.