-
1
-
-
38049100456
-
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
-
Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, et al. 2007. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci 104: 20007-20012.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 20007-20012
-
-
Beroukhim, R.1
Getz, G.2
Nghiemphu, L.3
Barretina, J.4
Hsueh, T.5
Linhart, D.6
Vivanco, I.7
Lee, J.C.8
Huang, J.H.9
Alexander, S.10
-
2
-
-
77249119762
-
The landscape of somatic copy-number alteration across human cancers
-
Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, et al. 2010. The landscape of somatic copy-number alteration across human cancers. Nature 463: 899-905.
-
(2010)
Nature
, vol.463
, pp. 899-905
-
-
Beroukhim, R.1
Mermel, C.H.2
Porter, D.3
Wei, G.4
Raychaudhuri, S.5
Donovan, J.6
Barretina, J.7
Boehm, J.S.8
Dobson, J.9
Urashima, M.10
-
3
-
-
0035923521
-
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
-
Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, et al. 2001. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci 98: 13790-13795.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 13790-13795
-
-
Bhattacharjee, A.1
Richards, W.G.2
Staunton, J.3
Li, C.4
Monti, S.5
Vasa, P.6
Ladd, C.7
Beheshti, J.8
Bueno, R.9
Gillette, M.10
-
4
-
-
44349191457
-
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
-
Campbell PJ, Stephens PJ, Pleasance ED, O'Meara S, Li H, Santarius T, Stebbings LA, Leroy C, Edkins S, Hardy C, et al. 2008. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat Genet 40: 722.
-
(2008)
Nat Genet
, vol.40
, pp. 722
-
-
Campbell, P.J.1
Stephens, P.J.2
Pleasance, E.D.3
O'Meara, S.4
Li, H.5
Santarius, T.6
Stebbings, L.A.7
Leroy, C.8
Edkins, S.9
Hardy, C.10
-
5
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network. 2008. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
6
-
-
58149218240
-
High-resolution mapping of copy-number alterations with massively parallel sequencing
-
Chiang DY, Getz G, Jaffe DB, O'Kelly MJT, Zhao X, Carter SL, Russ C, Nusbaum C, Meyerson M, Lander ES. 2009. High-resolution mapping of copy-number alterations with massively parallel sequencing. Nat Methods 6: 99-103.
-
(2009)
Nat Methods
, vol.6
, pp. 99-103
-
-
Chiang, D.Y.1
Getz, G.2
Jaffe, D.B.3
O'Kelly, M.J.T.4
Zhao, X.5
Carter, S.L.6
Russ, C.7
Nusbaum, C.8
Meyerson, M.9
Lander, E.S.10
-
7
-
-
33646007659
-
Small cell lung cancer: Treatment review
-
Cooper S, Spiro SG. 2006. Small cell lung cancer: treatment review. Respirology 11: 241-248.
-
(2006)
Respirology
, vol.11
, pp. 241-248
-
-
Cooper, S.1
Spiro, S.G.2
-
8
-
-
68149157175
-
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
-
DuPage M, Dooley AL, Jacks T. 2009. Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc 4: 1064-1072.
-
(2009)
Nat Protoc
, vol.4
, pp. 1064-1072
-
-
Dupage, M.1
Dooley, A.L.2
Jacks, T.3
-
9
-
-
0036177886
-
Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia
-
Gründer A, Ebel. TT, Mallo, M, Schwarzkopf, G, Shimizu, T, Sippel. AE, Schrewe, H. 2002. Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev 112: 69-77.
-
(2002)
Mech Dev
, vol.112
, pp. 69-77
-
-
Gründer, A.1
Ebel, T.T.2
Mallo, M.3
Schwarzkopf, G.4
Shimizu, T.5
Sippel, A.6
Schrewe, H.7
-
10
-
-
43049153163
-
DNA copy number alterations and expression of relevant genes in triple-negative breast cancer
-
Han W, Jung E-M, Cho J, Lee JW, Hwang K-T, Yang S-J, Kang JJ, Bae J-Y, Jeon YK, Park I-A, et al. 2008. DNA copy number alterations and expression of relevant genes in triple-negative breast cancer. Genes Chromosomes Cancer 47: 490-499.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 490-499
-
-
Han, W.1
Jung, E.-M.2
Cho, J.3
Lee, J.W.4
Hwang, K.-T.5
Yang, S.-J.6
Kang, J.J.7
Bae, J.-Y.8
Jeon, Y.K.9
Park, I.-A.10
-
11
-
-
0023686773
-
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
-
Harbour JW, Lai SL, Whang-Peng J, Gazdar AF, Minna JD, Kaye FJ. 1988. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241: 353-357.
-
(1988)
Science
, vol.241
, pp. 353-357
-
-
Harbour, J.W.1
Lai, S.L.2
Whang-Peng, J.3
Gazdar, A.F.4
Minna, J.D.5
Kaye, F.J.6
-
12
-
-
0035734285
-
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
Jonkers J, Meuwissen R, van der Gulden H, Peterse H, van der Valk M, Berns A. 2001. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet 29: 418-425.
-
(2001)
Nat Genet
, vol.29
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
van der Gulden, H.3
Peterse, H.4
van der Valk, M.5
Berns, A.6
-
13
-
-
33745288277
-
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene
-
Kim M, Gans JD, Nogueira, C,Wang, A, Paik, J-H, Feng, B, Brennan, C, Hahn, WC, Cordon-Cardo, C, Wagner, SN, et al. 2006. Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 125: 1269-1281.
-
(2006)
Cell
, vol.125
, pp. 1269-1281
-
-
Kim, M.1
Gans, J.D.2
Nogueira, C.3
Wang, A.4
Paik, J.-H.5
Feng, B.6
Brennan, C.7
Hahn, W.C.8
Cordon-Cardo, C.9
Wagner, S.N.10
-
14
-
-
3242791018
-
In silico p53 mutation hotspots in lung cancer
-
Lewis PD, Parry JM. 2004. In silico p53 mutation hotspots in lung cancer. Carcinogenesis 25: 1099-1107.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1099-1107
-
-
Lewis, P.D.1
Parry, J.M.2
-
15
-
-
55549101623
-
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
-
Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH, McGrath S, Hickenbotham M, et al. 2008. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456: 66-72.
-
(2008)
Nature
, vol.456
, pp. 66-72
-
-
Ley, T.J.1
Mardis, E.R.2
Ding, L.3
Fulton, B.4
McLellan, M.D.5
Chen, K.6
Dooling, D.7
Dunford-Shore, B.H.8
McGrath, S.9
Hickenbotham, M.10
-
16
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, Koboldt DC, Fulton RS, Delehaunty KD, McGrath SD, et al. 2009. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 361: 1058-1066.
-
(2009)
N Engl J Med
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
Larson, D.E.4
McLellan, M.D.5
Chen, K.6
Koboldt, D.C.7
Fulton, R.S.8
Delehaunty, K.D.9
McGrath, S.D.10
-
17
-
-
15444374561
-
Mouse models for human lung cancer
-
Meuwissen R, Berns A. 2005. Mouse models for human lung cancer. Genes Dev 19: 643-664.
-
(2005)
Genes Dev
, vol.19
, pp. 643-664
-
-
Meuwissen, R.1
Berns, A.2
-
18
-
-
0141523025
-
Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model
-
Meuwissen R, Linn SC, Linnoila RI, Zevenhoven J, Mooi WJ, Berns A. 2003. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer Cell 4: 181-189.
-
(2003)
Cancer Cell
, vol.4
, pp. 181-189
-
-
Meuwissen, R.1
Linn, S.C.2
Linnoila, R.I.3
Zevenhoven, J.4
Mooi, W.J.5
Berns, A.6
-
19
-
-
0022392771
-
L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer
-
Nau MM, Brooks BJ, Battey J, Sausville E, Gazdar AF, Kirsch IR, McBride OW, Bertness V, Hollis GF, Minna JD. 1985. L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer. Nature 318: 69-73.
-
(1985)
Nature
, vol.318
, pp. 69-73
-
-
Nau, M.M.1
Brooks, B.J.2
Battey, J.3
Sausville, E.4
Gazdar, A.F.5
Kirsch, I.R.6
McBride, O.W.7
Bertness, V.8
Hollis, G.F.9
Minna, J.D.10
-
20
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance ED, Stephens PJ, O'Meara S, McBride DJ, Meynert A, Jones D, Lin, M-L, Beare, D, Lau, KW, Greenman, C, et al. 2010. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 463: 184-190.
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
Stephens, P.J.2
O'Meara, S.3
McBride, D.J.4
Meynert, A.5
Jones, D.6
Lin, M.-L.7
Beare, D.8
Lau, K.W.9
Greenman, C.10
-
21
-
-
0038342441
-
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
-
Sage J, Miller AL, Perez-Mancera PA, Wysocki JM, Jacks T. 2003. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 424: 223-228.
-
(2003)
Nature
, vol.424
, pp. 223-228
-
-
Sage, J.1
Miller, A.L.2
Perez-Mancera, P.A.3
Wysocki, J.M.4
Jacks, T.5
-
22
-
-
0023739967
-
A family of human CCAAT-box-binding proteins active in transcription and DNA replication: Cloning and expression of multiple cDNAs
-
Santoro C, Mermod N, Andrews PC, Tjian R. 1988. A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature 334: 218-224.
-
(1988)
Nature
, vol.334
, pp. 218-224
-
-
Santoro, C.1
Mermod, N.2
Andrews, P.C.3
Tjian, R.4
-
23
-
-
77952794331
-
Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma
-
Schaffer BE, Park K-S, Yiu G, Conklin JF, Lin C, Burkhart DL, Karnezis AN, Sweet-Cordero EA, Sage J. 2010. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Res 70: 3877-3883.
-
(2010)
Cancer Res
, vol.70
, pp. 3877-3883
-
-
Schaffer, B.E.1
Park, K.-S.2
Yiu, G.3
Conklin, J.F.4
Lin, C.5
Burkhart, D.L.6
Karnezis, A.N.7
Sweet-Cordero, E.A.8
Sage, J.9
-
24
-
-
11844283949
-
The transcription factor gene Nfib is essential for both lung maturation and brain development
-
Steele-Perkins G, Plachez C, Butz KG, Yang G, Bachurski CJ, Kinsman SL, Litwack ED, Richards LJ, Gronostajski RM. 2005. The transcription factor gene Nfib is essential for both lung maturation and brain development. Mol Cell Biol 25: 685-698.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 685-698
-
-
Steele-Perkins, G.1
Plachez, C.2
Butz, K.G.3
Yang, G.4
Bachurski, C.J.5
Kinsman, S.L.6
Litwack, E.D.7
Richards, L.J.8
Gronostajski, R.M.9
-
25
-
-
0024452546
-
A Frequent Target For Genetic Abnormalities In Lung Cancer
-
Takahashi T, Nau MM, Chiba I, Birrer MJ, Rosenberg RK, Vinocour M, Levitt M, Pass H, Gazdar AF, Minna JD. 1989. p53: A frequent target for genetic abnormalities in lung cancer. Science 246: 491-494.
-
(1989)
Science
, vol.246
, pp. 491-494
-
-
Takahashi, T.1
Nau, M.M.2
Chiba, I.3
Birrer, M.J.4
Rosenberg, R.K.5
Vinocour, M.6
Levitt, M.7
Pass, H.8
Gazdar, A.F.9
Minna, J.D.10
-
26
-
-
0026068396
-
The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution pattern
-
Takahashi T, Takahashi T, Suzuki H, Hida T, Sekido Y, Ariyoshi Y, Ueda R. 1991. The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution pattern. Oncogene 6: 1775-1778.
-
(1991)
Oncogene
, vol.6
, pp. 1775-1778
-
-
Takahashi, T.1
Takahashi, T.2
Suzuki, H.3
Hida, T.4
Sekido, Y.5
Ariyoshi, Y.6
Ueda, R.7
-
27
-
-
0037220167
-
The TP53 gene, tobacco exposure, and lung cancer
-
Toyooka S, Tsuda T, Gazdar AF. 2003. The TP53 gene, tobacco exposure, and lung cancer. Hum Mutat 21: 229-239.
-
(2003)
Hum Mutat
, vol.21
, pp. 229-239
-
-
Toyooka, S.1
Tsuda, T.2
Gazdar, A.F.3
-
28
-
-
0037063164
-
Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells
-
Vooijs M, te Riele H, van der Valk M, Berns A. 2002. Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells. Oncogene 21: 4635-4645.
-
(2002)
Oncogene
, vol.21
, pp. 4635-4645
-
-
Vooijs, M.1
te Riele, H.2
van der Valk, M.3
Berns, A.4
-
29
-
-
77955634444
-
Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors
-
Voortman J, Lee JH, Killian JK, Suuriniemi M, Wang Y, Lucchi M, Smith WI Jr, Meltzer P, Giaccone G. 2010. Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors. Proc Natl Acad Sci 107: 13040-13045.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 13040-13045
-
-
Voortman, J.1
Lee, J.H.2
Killian, J.K.3
Suuriniemi, M.4
Wang, Y.5
Lucchi, M.6
Smith Jr., W.I.7
Meltzer, P.8
Giaccone, G.9
-
32
-
-
0345575500
-
Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung
-
Yokota J, Wada M, Shimosato Y, Terada M, Sugimura T. 1987. Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung. Proc Natl Acad Sci 84: 9252-9256.
-
(1987)
Proc Natl Acad Sci
, vol.84
, pp. 9252-9256
-
-
Yokota, J.1
Wada, M.2
Shimosato, Y.3
Terada, M.4
Sugimura, T.5
-
33
-
-
0023775771
-
Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung
-
Yokota J, Akiyama T, Fung Y-KT, Benedict WF, Namba Y, Hanaoka M, Wada M, Terasaki T, Shimosato Y, Sugimura T, et al. 1988. Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung. Oncogene 3: 471-475.
-
(1988)
Oncogene
, vol.3
, pp. 471-475
-
-
Yokota, J.1
Akiyama, T.2
Y-Kt, F.3
Benedict, W.F.4
Namba, Y.5
Hanaoka, M.6
Wada, M.7
Terasaki, T.8
Shimosato, Y.9
Sugimura, T.10
-
34
-
-
33745253109
-
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
-
Zender L, Spector MS, Xue W, Flemming P, Cordon-Cardo C, Silke J, Fan S-T, Luk JM, Wigler M, Hannon GJ, et al. 2006. Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 125: 1253-1267.
-
(2006)
Cell
, vol.125
, pp. 1253-1267
-
-
Zender, L.1
Spector, M.S.2
Xue, W.3
Flemming, P.4
Cordon-Cardo, C.5
Silke, J.6
Fan, S.-T.7
Luk, J.M.8
Wigler, M.9
Hannon, G.J.10
-
35
-
-
56349121125
-
An oncogenomicsbased in vivo RNAi screen identifies tumor suppressors in liver cancer
-
Zender L, Xue W, Zuber J, Semighini CP, Krasnitz A, Ma B, Zender P, Kubicka S, Luk JM, Schirmacher P, et al. 2008. An oncogenomicsbased in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 135: 852-864.
-
(2008)
Cell
, vol.135
, pp. 852-864
-
-
Zender, L.1
Xue, W.2
Zuber, J.3
Semighini, C.P.4
Krasnitz, A.5
Ma, B.6
Zender, P.7
Kubicka, S.8
Luk, J.M.9
Schirmacher, P.10
-
36
-
-
33748078111
-
Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer
-
Zhou Z, Flesken-Nikitin A, Corney DC, Wang W, Goodrich DW, Roy-Burman P, Nikitin AY. 2006. Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. Cancer Res 66: 7889-7898.
-
(2006)
Cancer Res
, vol.66
, pp. 7889-7898
-
-
Zhou, Z.1
Flesken-Nikitin, A.2
Corney, D.C.3
Wang, W.4
Goodrich, D.W.5
Roy-Burman, P.6
Nikitin, A.Y.7
|