Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF

PLoS ONE

Volumn 3, Issue 7, 2008, Pages

  Wellbrock, Claudia ^a   Rana, Sareena ^a   Paterson, Hugh ^a   Pickersgill, Helen ^b   Brummelkamp, Thijn ^b   Marais, Richard ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; OCTAMER TRANSCRIPTION FACTOR 4; BRAF PROTEIN, HUMAN; CDK2 PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; MITF PROTEIN, HUMAN;

ARTICLE; CANCER CELL; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; WILD TYPE; CELL CYCLE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELANOCYTES; MELANOMA; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; PROTO-ONCOGENE PROTEINS B-RAF; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 50549104987     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002734     Document Type: Article

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