-
1
-
-
80755138384
-
In melanoma, beta-catenin is a suppressor of invasion
-
Arozarena, I., Bischof, H., Gilby, D., Belloni, B., Dummer, R., and Wellbrock, C. (2011). In melanoma, beta-catenin is a suppressor of invasion. Oncogene 30, 4531-4543.
-
(2011)
Oncogene
, vol.30
, pp. 4531-4543
-
-
Arozarena, I.1
Bischof, H.2
Gilby, D.3
Belloni, B.4
Dummer, R.5
Wellbrock, C.6
-
2
-
-
33845711166
-
Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
-
Carreira, S., Goodall, J., Denat, L., Rodriguez, M., Nuciforo, P., Hoek, K.S., Testori, A., Larue, L., and Goding, C.R. (2006). Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev. 20, 3426-3439.
-
(2006)
Genes Dev.
, vol.20
, pp. 3426-3439
-
-
Carreira, S.1
Goodall, J.2
Denat, L.3
Rodriguez, M.4
Nuciforo, P.5
Hoek, K.S.6
Testori, A.7
Larue, L.8
Goding, C.R.9
-
3
-
-
84897482887
-
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
-
Cleary, A.S., Leonard, T.L., Gestl, S.A., and Gunther, E.J. (2014). Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers. Nature 508, 113-117.
-
(2014)
Nature
, vol.508
, pp. 113-117
-
-
Cleary, A.S.1
Leonard, T.L.2
Gestl, S.A.3
Gunther, E.J.4
-
4
-
-
59149097344
-
Mechanically activated integrin switch controls alpha5beta1 function
-
Friedland, J.C., Lee, M.H., and Boettiger, D. (2009). Mechanically activated integrin switch controls alpha5beta1 function. Science 323, 642-644.
-
(2009)
Science
, vol.323
, pp. 642-644
-
-
Friedland, J.C.1
Lee, M.H.2
Boettiger, D.3
-
5
-
-
14844334889
-
HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1
-
Gaggioli, C., Deckert, M., Robert, G., Abbe, P., Batoz, M., Ehrengruber, M.U., Ortonne, J.P., Ballotti, R., and Tartare-Deckert, S. (2005). HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1. Oncogene 24, 1423-1433.
-
(2005)
Oncogene
, vol.24
, pp. 1423-1433
-
-
Gaggioli, C.1
Deckert, M.2
Robert, G.3
Abbe, P.4
Batoz, M.5
Ehrengruber, M.U.6
Ortonne, J.P.7
Ballotti, R.8
Tartare-Deckert, S.9
-
6
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
Gaggioli, C., Hooper, S., Hidalgo-Carcedo, C., Grosse, R., Marshall, J.F., Harrington, K., and Sahai, E. (2007). Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat. Cell Biol. 9, 1392-1400.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 1392-1400
-
-
Gaggioli, C.1
Hooper, S.2
Hidalgo-Carcedo, C.3
Grosse, R.4
Marshall, J.F.5
Harrington, K.6
Sahai, E.7
-
7
-
-
84856013431
-
Clonal evolution in cancer
-
Greaves, M., and Maley, C.C. (2012). Clonal evolution in cancer. Nature 481, 306-313.
-
(2012)
Nature
, vol.481
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
8
-
-
78049237405
-
Cancer stem cells versus phenotypeswitching in melanoma
-
Hoek, K.S., and Goding, C.R. (2010). Cancer stem cells versus phenotypeswitching in melanoma. Pigment Cell Melanoma Res 23, 746-759.
-
(2010)
Pigment Cell Melanoma Res
, vol.23
, pp. 746-759
-
-
Hoek, K.S.1
Goding, C.R.2
-
9
-
-
33745753404
-
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature
-
Hoek, K.S., Schlegel, N.C., Brafford, P., Sucker, A., Ugurel, S., Kumar, R., Weber, B.L., Nathanson, K.L., Phillips, D.J., Herlyn, M., et al. (2006). Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Res. 19, 290-302.
-
(2006)
Pigment Cell Res.
, vol.19
, pp. 290-302
-
-
Hoek, K.S.1
Schlegel, N.C.2
Brafford, P.3
Sucker, A.4
Ugurel, S.5
Kumar, R.6
Weber, B.L.7
Nathanson, K.L.8
Phillips, D.J.9
Herlyn, M.10
-
10
-
-
38849203228
-
In vivo switching of human melanoma cells between proliferative and invasive states
-
Hoek, K.S., Eichhoff, O.M., Schlegel, N.C., Döbbeling, U., Kobert, N., Schaerer, L., Hemmi, S., and Dummer, R. (2008). In vivo switching of human melanoma cells between proliferative and invasive states. Cancer Res. 68, 650-656.
-
(2008)
Cancer Res.
, vol.68
, pp. 650-656
-
-
Hoek, K.S.1
Eichhoff, O.M.2
Schlegel, N.C.3
Döbbeling, U.4
Kobert, N.5
Schaerer, L.6
Hemmi, S.7
Dummer, R.8
-
11
-
-
84856862054
-
Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer
-
Hou, J.M., Krebs, M.G., Lancashire, L., Sloane, R., Backen, A., Swain, R.K., Priest, L.J., Greystoke, A., Zhou, C., Morris, K., et al. (2012). Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer. J. Clin. Oncol. 30, 525-532.
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 525-532
-
-
Hou, J.M.1
Krebs, M.G.2
Lancashire, L.3
Sloane, R.4
Backen, A.5
Swain, R.K.6
Priest, L.J.7
Greystoke, A.8
Zhou, C.9
Morris, K.10
-
12
-
-
84875768260
-
Potentiation of tumor cell invasion by co-culture with monocytes accompanying enhanced production of matrix metalloproteinase and fibronectin
-
Kamoshida, G., Matsuda, A., Miura, R., Takashima, Y., Katsura, A., and Tsuji, T. (2013). Potentiation of tumor cell invasion by co-culture with monocytes accompanying enhanced production of matrix metalloproteinase and fibronectin. Clin. Exp. Metastasis 30, 289-297.
-
(2013)
Clin. Exp. Metastasis
, vol.30
, pp. 289-297
-
-
Kamoshida, G.1
Matsuda, A.2
Miura, R.3
Takashima, Y.4
Katsura, A.5
Tsuji, T.6
-
13
-
-
84891960876
-
Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanoma
-
Khoja, L., Shenjere, P., Hodgson, C., Hodgetts, J., Clack, G., Hughes, A., Lorigan, P., and Dive, C. (2014). Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanoma. Melanoma Res. 24, 40-46.
-
(2014)
Melanoma Res.
, vol.24
, pp. 40-46
-
-
Khoja, L.1
Shenjere, P.2
Hodgson, C.3
Hodgetts, J.4
Clack, G.5
Hughes, A.6
Lorigan, P.7
Dive, C.8
-
14
-
-
0032886830
-
Microphthalmia transcription factor. A sensitive and specific melanocyte marker for MelanomaDiagnosis
-
King, R., Weilbaecher, K.N., McGill, G., Cooley, E., Mihm, M., and Fisher, D.E. (1999). Microphthalmia transcription factor. A sensitive and specific melanocyte marker for MelanomaDiagnosis. Am. J. Pathol. 155, 731-738.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 731-738
-
-
King, R.1
Weilbaecher, K.N.2
McGill, G.3
Cooley, E.4
Mihm, M.5
Fisher, D.E.6
-
15
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
Levental, K.R., Yu, H., Kass, L., Lakins, J.N., Egeblad, M., Erler, J.T., Fong, S.F., Csiszar, K., Giaccia, A., Weninger, W., et al. (2009). Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 139, 891-906.
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Kass, L.3
Lakins, J.N.4
Egeblad, M.5
Erler, J.T.6
Fong, S.F.7
Csiszar, K.8
Giaccia, A.9
Weninger, W.10
-
16
-
-
79959635610
-
Senescent cells develop a PARP-1 and nuclear factor-kappaB-associated secretome (PNAS)
-
Ohanna, M., Giuliano, S., Bonet, C., Imbert, V., Hofman, V., Zangari, J., Bille, K., Robert, C., Bressac-de Paillerets, B., Hofman, P., et al. (2011). Senescent cells develop a PARP-1 and nuclear factor-kappaB-associated secretome (PNAS). Genes Dev. 25, 1245-1261.
-
(2011)
Genes Dev.
, vol.25
, pp. 1245-1261
-
-
Ohanna, M.1
Giuliano, S.2
Bonet, C.3
Imbert, V.4
Hofman, V.5
Zangari, J.6
Bille, K.7
Robert, C.8
Bressac-de Paillerets, B.9
Hofman, P.10
-
17
-
-
33846782878
-
Collagen reorganization at the tumor-stromal interface facilitates local invasion
-
Provenzano, P.P., Eliceiri, K.W., Campbell, J.M., Inman, D.R., White, J.G., and Keely, P.J. (2006). Collagen reorganization at the tumor-stromal interface facilitates local invasion. BMC Med. 4, 38.
-
(2006)
BMC Med.
, vol.4
, pp. 38
-
-
Provenzano, P.P.1
Eliceiri, K.W.2
Campbell, J.M.3
Inman, D.R.4
White, J.G.5
Keely, P.J.6
-
18
-
-
0037226593
-
A molecular signature of metastasis in primary solid tumors
-
Ramaswamy, S., Ross, K.N., Lander, E.S., and Golub, T.R. (2003). A molecular signature of metastasis in primary solid tumors. Nat. Genet. 33, 49-54.
-
(2003)
Nat. Genet.
, vol.33
, pp. 49-54
-
-
Ramaswamy, S.1
Ross, K.N.2
Lander, E.S.3
Golub, T.R.4
-
19
-
-
77957585010
-
Metastasis in an orthotopic murine model of melanoma is independent of RAS/RAF mutation
-
Rozenberg, G.I., Monahan, K.B., Torrice, C., Bear, J.E., and Sharpless, N.E. (2010). Metastasis in an orthotopic murine model of melanoma is independent of RAS/RAF mutation. Melanoma Res. 20, 361-371.
-
(2010)
Melanoma Res.
, vol.20
, pp. 361-371
-
-
Rozenberg, G.I.1
Monahan, K.B.2
Torrice, C.3
Bear, J.E.4
Sharpless, N.E.5
-
20
-
-
9444290419
-
Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP
-
Sabeh, F., Ota, I., Holmbeck, K., Birkedal-Hansen, H., Soloway, P., Balbin, M., Lopez-Otin, C., Shapiro, S., Inada, M., Krane, S., et al. (2004). Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J. Cell Biol. 167, 769-781.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 769-781
-
-
Sabeh, F.1
Ota, I.2
Holmbeck, K.3
Birkedal-Hansen, H.4
Soloway, P.5
Balbin, M.6
Lopez-Otin, C.7
Shapiro, S.8
Inada, M.9
Krane, S.10
-
21
-
-
0042354574
-
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
-
Sahai, E., and Marshall, C.J. (2003). Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat. Cell Biol. 5, 711-719.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 711-719
-
-
Sahai, E.1
Marshall, C.J.2
-
22
-
-
84866324123
-
Cancer stem cells and epithelialmesenchymal transition: concepts and molecular links
-
Scheel, C., and Weinberg, R.A. (2012). Cancer stem cells and epithelialmesenchymal transition: concepts and molecular links. Semin. Cancer Biol. 22, 396-403.
-
(2012)
Semin. Cancer Biol.
, vol.22
, pp. 396-403
-
-
Scheel, C.1
Weinberg, R.A.2
-
23
-
-
0036796746
-
Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions
-
Sottile, J., and Hocking, D.C. (2002). Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions. Mol. Biol. Cell 13, 3546-3559.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3546-3559
-
-
Sottile, J.1
Hocking, D.C.2
-
24
-
-
57749092869
-
Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth
-
Tsuji, T., Ibaragi, S., Shima, K., Hu, M.G., Katsurano, M., Sasaki, A., and Hu, G.F. (2008). Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth. Cancer Res. 68, 10377-10386.
-
(2008)
Cancer Res.
, vol.68
, pp. 10377-10386
-
-
Tsuji, T.1
Ibaragi, S.2
Shima, K.3
Hu, M.G.4
Katsurano, M.5
Sasaki, A.6
Hu, G.F.7
-
25
-
-
78650034777
-
Towards a knowledge-based Human Protein Atlas
-
Uhlen, M., Oksvold, P., Fagerberg, L., Lundberg, E., Jonasson, K., Forsberg, M., Zwahlen, M., Kampf, C., Wester, K., Hober, S., et al. (2010). Towards a knowledge-based Human Protein Atlas. Nat. Biotechnol. 28, 1248-1250.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1248-1250
-
-
Uhlen, M.1
Oksvold, P.2
Fagerberg, L.3
Lundberg, E.4
Jonasson, K.5
Forsberg, M.6
Zwahlen, M.7
Kampf, C.8
Wester, K.9
Hober, S.10
-
26
-
-
84865186133
-
Comparative genomic analysis of primary versus metastatic colorectal carcinomas
-
Vakiani, E., Janakiraman, M., Shen, R., Sinha, R., Zeng, Z., Shia, J., Cercek, A., Kemeny, N., D'Angelica, M., Viale, A., et al. (2012). Comparative genomic analysis of primary versus metastatic colorectal carcinomas. J. Clin. Oncol. 30, 2956-2962.
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2956-2962
-
-
Vakiani, E.1
Janakiraman, M.2
Shen, R.3
Sinha, R.4
Zeng, Z.5
Shia, J.6
Cercek, A.7
Kemeny, N.8
D'Angelica, M.9
Viale, A.10
-
27
-
-
84880240161
-
Nextgeneration sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with nonsmall-cell lung cancer
-
Vignot, S., Frampton, G.M., Soria, J.C., Yelensky, R., Commo, F., Brambilla, C., Palmer, G., Moro-Sibilot, D., Ross, J.S., Cronin, M.T., et al. (2013). Nextgeneration sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with nonsmall-cell lung cancer. J. Clin. Oncol. 31, 2167-2172.
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 2167-2172
-
-
Vignot, S.1
Frampton, G.M.2
Soria, J.C.3
Yelensky, R.4
Commo, F.5
Brambilla, C.6
Palmer, G.7
Moro-Sibilot, D.8
Ross, J.S.9
Cronin, M.T.10
-
28
-
-
84863337617
-
Clonal architecture of secondary acute myeloid leukemia
-
Walter, M.J., Shen, D., Ding, L., Shao, J., Koboldt, D.C., Chen, K., Larson, D.E., McLellan, M.D., Dooling, D., Abbott, R., et al. (2012). Clonal architecture of secondary acute myeloid leukemia. N. Engl. J. Med. 366, 1090-1098.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 1090-1098
-
-
Walter, M.J.1
Shen, D.2
Ding, L.3
Shao, J.4
Koboldt, D.C.5
Chen, K.6
Larson, D.E.7
McLellan, M.D.8
Dooling, D.9
Abbott, R.10
-
29
-
-
77954218212
-
BRAF as therapeutic target in melanoma
-
Wellbrock, C., and Hurlstone, A. (2010). BRAF as therapeutic target in melanoma. Biochem. Pharmacol. 80, 561-567.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 561-567
-
-
Wellbrock, C.1
Hurlstone, A.2
-
30
-
-
0037455576
-
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis
-
Wolf, K., Mazo, I., Leung, H., Engelke, K., von Andrian, U.H., Deryugina, E.I., Strongin, A.Y., Bröcker, E.B., and Friedl, P. (2003). Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J. Cell Biol. 160, 267-277.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 267-277
-
-
Wolf, K.1
Mazo, I.2
Leung, H.3
Engelke, K.4
von Andrian, U.H.5
Deryugina, E.I.6
Strongin, A.Y.7
Bröcker, E.B.8
Friedl, P.9
-
31
-
-
34547569807
-
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
-
Wolf, K., Wu, Y.I., Liu, Y., Geiger, J., Tam, E., Overall, C., Stack, M.S., and Friedl, P. (2007). Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat. Cell Biol. 9, 893-904.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 893-904
-
-
Wolf, K.1
Wu, Y.I.2
Liu, Y.3
Geiger, J.4
Tam, E.5
Overall, C.6
Stack, M.S.7
Friedl, P.8
-
32
-
-
84880028245
-
Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force
-
Wolf, K., Te Lindert, M., Krause, M., Alexander, S., Te Riet, J., Willis, A.L., Hoffman, R.M., Figdor, C.G., Weiss, S.J., and Friedl, P. (2013). Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J. Cell Biol. 201, 1069-1084.
-
(2013)
J. Cell Biol.
, vol.201
, pp. 1069-1084
-
-
Wolf, K.1
Te Lindert, M.2
Krause, M.3
Alexander, S.4
Te Riet, J.5
Willis, A.L.6
Hoffman, R.M.7
Figdor, C.G.8
Weiss, S.J.9
Friedl, P.10
-
33
-
-
75749106942
-
Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion
-
Wu, M., Pastor-Pareja, J.C., and Xu, T. (2010). Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature 463, 545-548.
-
(2010)
Nature
, vol.463
, pp. 545-548
-
-
Wu, M.1
Pastor-Pareja, J.C.2
Xu, T.3
-
34
-
-
84873811988
-
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
-
Yu, M., Bardia, A., Wittner, B.S., Stott, S.L., Smas, M.E., Ting, D.T., Isakoff, S.J., Ciciliano, J.C., Wells, M.N., Shah, A.M., et al. (2013). Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science 339, 580-584.
-
(2013)
Science
, vol.339
, pp. 580-584
-
-
Yu, M.1
Bardia, A.2
Wittner, B.S.3
Stott, S.L.4
Smas, M.E.5
Ting, D.T.6
Isakoff, S.J.7
Ciciliano, J.C.8
Wells, M.N.9
Shah, A.M.10
|