Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Nature Communications

Volumn 6, Issue , 2015, Pages

  Verfaillie, Annelien ^a   Imrichova, Hana ^a   Atak, Zeynep Kalender ^a   Dewaele, Michael ^b,c   Rambow, Florian ^b,c   Hulselmans, Gert ^a   Christiaens, Valerie ^a   Svetlichnyy, Dmitry ^a   Luciani, Flavie ^b,c   Van Den Mooter, Laura ^a,c   Claerhout, Sofie ^a,c   Fiers, Mark ^c   Journe, Fabrice ^d   Ghanem, Ghanem Elias ^d   Herrmann, Carl ^e   Halder, Georg ^a,c   Marine, Jean Christophe ^b,c   Aerts, Stein ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d JULES BORDET INSTITUTE   (Belgium)

^e Medical Oncology Clinic Institut Jules Bordet Université Libre de Bruxelles ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PROTEIN; SELUMETINIB; TEAD PROTEIN; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR SOX10; TRANSCRIPTOME; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CHROMATIN; DNA BINDING PROTEIN; HISTONE; ISOPROTEIN; MITF PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN KINASE INHIBITOR; SMALL INTERFERING RNA; SOX10 PROTEIN, HUMAN; TEAD1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SOX;

GENE EXPRESSION; INHIBITOR; MUTATION; PHENOTYPE; PROTEIN; TUMOR;

ARTICLE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SUBPOPULATION; CELL VIABILITY; CHROMATIN; COMPUTER MODEL; CONTROLLED STUDY; DNA BINDING MOTIF; DNA METHYLATION; E BOX ELEMENT; ENHANCER REGION; GENE CONTROL; GENE EXPRESSION; GENE MAPPING; GENE ONTOLOGY; GENE REGULATORY NETWORK; GENE SILENCING; HISTONE MODIFICATION; HUMAN; HUMAN CELL; MELANOMA; PHENOTYPE; PROMOTER REGION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION SITE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR BIOPSY; ANTAGONISTS AND INHIBITORS; CELL TRANSFORMATION; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NUCLEAR REPROGRAMMING; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CELLULAR REPROGRAMMING; CHROMATIN; DNA METHYLATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HISTONES; HUMANS; MELANOMA; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; PROTEIN ISOFORMS; PROTEIN KINASE INHIBITORS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SOXE TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 84925425377     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7683     Document Type: Article

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