An Allyl Protection and Improved Purification Strategy Enables the Synthesis of Functionalized Phosphonamidate Peptides

Synthesis (Germany)

Volumn 49, Issue 8, 2017, Pages 1857-1866

  Cramer, Jonathan ^a   Klebe, Gerhard ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

allyl alloc protection; inhibitor synthesis; metalloprotease; phosphonamidate; solid phase extraction; thermolysin

Indexed keywords

PEPTIDES; PHASE SEPARATION; PURIFICATION; SYNTHESIS (CHEMICAL);

ALLYL/ALLOC PROTECTION; METALLO-PROTEASE; PHOSPHONAMIDATE; SOLID-PHASE EXTRACTION; THERMOLYSIN;

EXTRACTION;

BENZYL [[(ALLYLOXY)(HYDROXY)PHOSPHORYL]METHYL]CARBAMIC ACID; BENZYL [[BIS(ALLYLOXY)PHOSPHORYL]METHYL]CARBAMIC ACID; CARBAMIC ACID; COMPOUND 10; COMPOUND 11; COMPOUND 12; COMPOUND 13; COMPOUND 14; COMPOUND 15; COMPOUND 16; COMPOUND 17; COMPOUND 18; COMPOUND 19; COMPOUND 21; COMPOUND 22; COMPOUND 23; COMPOUND 24; COMPOUND 25; COMPOUND 4; COMPOUND 5; COMPOUND 6; COMPOUND 7; COMPOUND 8; COMPOUND 9; ESTER; N (5 BENZAMIDO 4 OXO 6 PHENYLHEXANOYL)PROLINE; PEPTIDE; PHOSPHONAMIDATE PEPTIDE; THERMOLYSIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; PURIFICATION; SOLID PHASE EXTRACTION;

EID: 85009971479     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0036-1588393     Document Type: Article

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