Chemoselective bioconjugation of triazole phosphonites in aqueous media

Chemistry - A European Journal

Volumn 21, Issue 3, 2015, Pages 970-974

  Vallée, M Robert J ^a   Majkut, Paul ^a   Krause, Dagmar ^a   Gerrits, Michael ^c   Hackenberger, Christian P R ^a,b  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c RiNA GmbH   (Germany)

Author keywords

Bioorthogonal; Chemoselectivity; Phosphonites; Protein conjugation; Staudinger reaction

Indexed keywords

BINDING ENERGY; CELL IMMOBILIZATION; NITROGEN COMPOUNDS; T-CELLS;

BIOORTHOGONAL; CHEMO-SELECTIVITY; PHOSPHONITES; PROTEIN CONJUGATIONS; STAUDINGER REACTIONS;

PROTEINS;

ALKYNE; AZIDE; COPPER; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PEPTIDE; PHOSPHOROUS ACID; RASA1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRIAZOLE DERIVATIVE; WATER;

CATALYSIS; CHEMISTRY; HUMAN; METABOLISM; SRC HOMOLOGY DOMAIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALKYNES; AZIDES; CATALYSIS; COPPER; HUMANS; P120 GTPASE ACTIVATING PROTEIN; PEPTIDES; PHOSPHOROUS ACIDS; SRC HOMOLOGY DOMAINS; TRIAZOLES; WATER;

EID: 84920849638     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201404690     Document Type: Article

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